Lifeboat Foundation

Research led by UC Riverside is making it easier to detect and capture DNA from fluid samples such as blood using a tiny glass tube and electric current. The technique, described in the journal Nanoscale, can also improve cancer diagnosis in the future.

DNA, a double-stranded, electrically charged molecule that contains all the information an organism needs to create and organize the building blocks of life, is tightly folded within the cell nucleus. Extracting the DNA from a single cell is time consuming and impractical for many medical and scientific purposes. Fortunately, as cells die naturally, their membranes burst, releasing the contents, including DNA. This means that a blood sample, for example, contains many strands of free-floating DNA that should, in theory, be easier to identify and extract in quantity.

Brazil daily Covid deaths top 4000 for first time.

Hospitals are overcrowded, with people dying as they wait for treatment, as cases continue to surge.

Circa 2017

When surgeons complete a successful lung operation, everyone should breathe a sigh of relief. But real relief may not come until weeks or even months later, when doctors remove the patient’s lingering sutures or staples. And that’s assuming there were no leakages, which can send a patient right back to the hospital.

Nasim Annabi, assistant professor of chemical engineering, has a better solution: a new type of surgical glue that could replace the need for staples and sutures altogether. Annabi is leading the research, which she and her colleagues from the University of Sydney and Harvard Medical School described in a paper published Wednesday in Science Translational Medicine.

Continue reading “Researchers develop surgical glue that seals wounds in seconds” »

O,.o.

The largest-ever study of almost 2000 DNA samples carried out by researchers at Pompeu Fabra university (UPF) in Barcelona has confirmed the “genetic singularity” of the Basques in Europe. The investigation, however, found that this difference only began to emerge 2500 years ago in the Iron Age. “Our analyses confirm that Basques were influenced by the major migration waves in Europe until the Iron Age, in a similar pattern as their surrounding populations,” the authors explain in the study published in the journal Current Biology.

The origin of the Basques has fascinated the scientific community since the 19th century. The French anthropologist Paul Broca snuck into a Basque cemetery one night in 1862 to steal skulls he wanted to study for their supposed genetic differences. Juan José Ibarretxe, premier of the Basque regional government until 2009, proclaimed that the Basque people “have existed for 7000 years” to promote his vision of an independent Basque state. And the then-president of the Basque Nationalist Party (PNV), Xabier Arzalluz, claimed in 2000 that the Basques were “the oldest inhabitants of Europe,” with “their own roots” since prehistoric times.

Continue reading “Basque ‘genetic singularity’ confirmed in largest-ever study” »

A woman in Pittsburgh has become the first documented case in a living person of an unusual medical condition where alcohol naturally brews in the bladder from the fermentation of yeast.

The condition, which researchers propose to call either ‘bladder fermentation syndrome’ or ‘urinary auto-brewery syndrome’, is similar to another incredibly rare condition, auto-brewery syndrome, where simply ingesting carbohydrates can be enough to make you inebriated, even without consuming any alcohol via regular means.

In the case, doctors became aware of what seems to be a related syndrome, after attending upon a 61-year-old patient who presented with liver damage and poorly controlled diabetes.

Remote-controlled Venus flytrap “robo-plants” and crops that tell farmers when they are hit by disease could become reality after scientists developed a high-tech system for communicating with vegetation.

Researchers in Singapore linked up plants to electrodes capable of monitoring the weak electrical pulses naturally emitted by the greenery.

The scientists used the technology to trigger a Venus flytrap to snap its jaws shut at the push of a button on a smartphone app.

Summary: Dopamine neurons largely rely on their own discharge to determine release rates of the hormone, researchers report.

Source: NYU Langone.

In addition to smoothing out wrinkles, researchers have found that the drug Botox can reveal the inner workings of the brain. A new study used it to show that feedback from individual nerve cells controls the release of dopamine, a chemical messenger involved in motivation, memory, and movement.

“Before we began this study, we had extensive data showing that spaceflight completely reprogrammed Salmonella at every level to become a better pathogen,”

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

Now, in the first study of its kind, Cheryl Nickerson, lead author Jennifer Barrila, and their colleagues describe the infection of human cells by the intestinal pathogen Salmonella Typhimurium during spaceflight. They show how the microgravity environment of spaceflight changes the molecular profile of human intestinal cells and how these expression patterns are further changed in response to infection. In another first, the researchers were also able to detect molecular changes in the bacterial pathogen while inside the infected host cells.

Continue reading “First Infection of Human Cells During Spaceflight Analyzed” »

Klas Moser.

What Musk is doing beside realizing his own dreams is inspiring thousands of young bright kids to keep on studying to realize their own dreams and I am sure that this is exactly what we humans need to create a better world on Earth as well.

This whol… See More.

Continue reading “CRISPR-Chip advance streamlines genetic testing for medical diagnostics and research” »