Lifeboat Foundation

When combined with other materials, it makes surprisingly strong bricks.

Researchers made a surprisingly strong building material from a combination of human blood, sweat, tears, and dust. It could help construct buildings on Mars.

The selected companies will develop lander design concepts, evaluating their performance, design, construction standards, mission assurance requirements, interfaces, safety, crew health accommodations, and medical capabilities. The companies will also mitigate lunar lander risks by conducting critical component tests and advancing the maturity of key technologies.

The work from these companies will ultimately help shape the strategy and requirements for a future NASA’s solicitation to provide regular astronaut transportation from lunar orbit to the surface of the Moon.

Data collected from 18 states between March and August suggest the Pfizer-BioNTech vaccine reduces the risk of being hospitalized with COVID-19 by 91% in the first four months after receiving the second dose. Beyond 120 days, however, that vaccine efficacy drops to 77%.

Meanwhile, Moderna’s vaccine was 93% effective at reducing the short-term risk of COVID-19 hospitalization and remained 92% effective after 120 days.

Moderna’s COVID-19 vaccine does a significantly better job of preventing COVID-19 hospitalizations compared with Pfizer’s shot.

A newly discovered manipulation mechanism used by parasitic bacteria to slow down plant aging, may offer new ways to protect disease-threatened food crops.

Parasites manipulate the organisms they live off to suit their needs, sometimes in drastic ways. When under the spell of a parasite, some plants undergo such extensive changes that they are described as “zombies”. They stop reproducing and serve only as a habitat and host for the parasitic pathogens.

Until now, there’s been little understanding of how this happens on a molecular and mechanistic level.

“You may hit the tipping point when you’re 50; it may happen when you’re 80; it may never happen,” Schindler said. “But once you pass the tipping point, you’re going to accumulate high levels of amyloid that are likely to cause dementia. If we know how much amyloid someone has right now, we can calculate how long ago they hit the tipping point and estimate how much longer it will be until they are likely to develop symptoms.”

Summary: A new algorithm uses neuroimaging data of amyloid levels in the brain and takes into account a person’s age to determine when a person with genetic Alzheimer’s risk factors, and with no signs of cognitive decline, will develop the disease.

Source; WUSTL

Continue reading “Time Until Dementia Symptoms Appear Can Be Estimated via Brain Scan” »

The TV show “Star Trek: The Next Generation” introduced millions of people to the idea of a holodeck: an immersive, realistic 3D holographic projection of a complete environment that you could interact with and even touch.

In the 21st century, holograms are already being used in a variety of ways such as medical systems, education, art, security and defense. Scientists are still developing ways to use lasers, modern digital processors, and motion-sensing technologies to create several different types of holograms which could change the way we interact.

My colleagues and I working in the University of Glasgow’s bendable electronics and sensing technologies research group have now developed a system of holograms of people using “aerohaptics,” creating feelings of touch with jets of air. Those jets of air deliver a sensation of touch on people’s fingers, hands and wrists.

Summary: A newly identified gene therapy pathway has the potential to protect us against dementia and cancer, researchers report.

Source: University of Sheffield.

Researchers from the University of Sheffield have discovered a new gene therapy pathway that has uncovered an important regulatory mechanism to keep our genome healthy. This pathway has the potential to protect us against serious life-limiting diseases such as cancer and dementia.

The existential threat of COVID-19 has highlighted an acute need to develop working therapeutics against emerging health threats. One of the luxuries deep learning has afforded us is the ability to modify the landscape as it unfolds — so long as we can keep up with the viral threat, and access the right data.

As with all new medical maladies, oftentimes the data needs time to catch up, and the virus takes no time to slow down, posing a difficult challenge as it can quickly mutate and become resistant to existing drugs. This led scientists from MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL) to ask: how can we identify the right synergistic drug combinations for the rapidly spreading SARS-CoV-2?

Typically, data scientists use deep learning to pick out drug combinations with large existing datasets for things like cancer and cardiovascular disease, but, understandably, they can’t be used for new illnesses with limited data.

University of California-Riverside (UCR) researchers say they are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.

One of the challenges with this new technology is that it must be kept cold to maintain stability during transport and storage. If this new project is successful, plant-based mRNA vaccines, which can be eaten, could overcome this challenge with the ability to be stored at room temperature.

The project’s goals, made possible by a $500,000 grant from the National Science Foundation, are threefold: showing that DNA containing the mRNA vaccines can be successfully delivered into the part of plant cells where it will replicate, demonstrating the plants can produce enough mRNA to rival a traditional shot, and finally, determining the right dosage.