Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 1,128

Google’s Sergey Brin talks AI safety efforts to prevent ‘sci-fi style sentience’

Google co-founder Sergey Brin has taken a rather similar stance as Tesla CEO Elon Musk on artificial intelligence, emphasizing AI dangers in a recent investor communication. According to the Russian-born billionaire, the present day is an era of possibilities, but it is also a time when responsibility has to be practiced, particularly when it comes to emerging technologies.

“We’re in an era of great inspiration and possibility, but with this opportunity comes the need for tremendous thoughtfulness and responsibility as technology is deeply and irrevocably interwoven into our societies,” he wrote.

Brin’s statements were outlined in Alphabet’s recent Founders’ Letter, where the 44-year-old billionaire described how Google is utilizing bleeding-edge technology for its ventures. While AI as a discipline is still an emerging field, Brin noted that there are already a lot of everyday applications for the technology. Among these are the algorithms utilized by Waymo’s self-driving cars, the smart cooling units of Google’s data centers, and of course, Google Translate and YouTube’s automatic captions.

We’ve just discovered a new part of the brain’s waste disposal system

In 2012, Nedergaard also helped to discover a network of thin tubes that collect waste fluid from brain cells, known as the glymphatic system. These tubes may drain into the outgoing cerebrospinal fluid, says Nedergaard.

The waste products of brain cells include proteins called beta-amyloid and tau that are thought to be involved in Alzheimer’s disease when they build up in excessive amounts.

In both mice and people, the SLYM also contains immune cells, so it may allow them to detect signs of infection present in the cerebrospinal fluid, says Nedergaard. “It is loaded with immune cells.”

A New Approach to Halting the Effects of Aging: Boosting Immune Cells Improves Brain Waste Clearance

Many neurodegenerative diseases, including Alzheimer’s.

Alzheimer’s disease is a disease that attacks the brain, causing a decline in mental ability that worsens over time. It is the most common form of dementia and accounts for 60 to 80 percent of dementia cases. There is no current cure for Alzheimer’s disease, but there are medications that can help ease the symptoms.

Jeff Lichtman (Harvard) Part 2: Neuromuscular Connectomics

The Connectome and Connectomics: Seeking Neural Circuit Motifs

Talk Overview: The human brain is extremely complex with much greater structural and functional diversity than other organs and this complexity is determined both by one’s experiences and one’s genes. In Part 1 of his talk, Lichtman explains how mapping the connections in the brain (the connectome) may lead to a better understanding of brain function. Together with his colleagues, Lichtman has developed tools to label individual cells in the nervous system with different colors producing beautiful and revealing maps of the neuronal connections.
Using transgenic mice with differently colored, fluorescently labeled proteins in each neuron (Brainbow mice), Lichtman and his colleagues were able to follow the formation and destruction of neuromuscular junctions during mouse development. This work is the focus of Part 2.
In Part 3, Lichtman asks whether some day it might be possible to map all of the neural connections in the brain. He describes the technical advances that have allowed him and his colleagues to begin this endeavor as well as the enormous challenges to deciphering the brain connectome.

Speaker Bio: Jeff Lichtman’s interest in how specific neuronal connections are made and maintained began while he was a MD-PhD student at Washington University in Saint Louis. Lichtman remained at Washington University for nearly 30 years. In 2004, he moved to Harvard University where he is Professor of Molecular and Cellular Biology and a member of the Center for Brain Science.
A major focus of Lichtman’s current research is to decode the map of all the neural connections in the brain. To this end, Lichtman and his colleagues have developed exciting new tools and techniques such as “Brainbow” mice and automated ultra thin tissue slicing machines.

Consumer Health: Do you know the symptoms of glaucoma?

January is National Glaucoma Awareness Month, which makes this a good time to learn more about treating this group of eye conditions.

About 3 million people in the U.S. have glaucoma, and it’s the second-leading cause of blindness worldwide, according to the Centers for Disease Control and Prevention.

Glaucoma is a group of eye conditions that damage the optic nerve, often due to abnormally high pressure in your eye. Elevated eye pressure is due to a buildup of the fluid that flows throughout the inside of your eye. When this fluid is overproduced or the drainage system doesn’t work properly, the fluid can’t flow out at its normal rate and eye pressure increases.

Scientists Have Decrypted the “Mechanical Code” of DNA

An international team of researchers, led by Durham University in the UK, has uncovered previously unknown ways in which nature encodes biological information in a DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).