Lifeboat Foundation

All memory storage devices, from your brain to the RAM in your computer, store information by changing their physical qualities. Over 130 years ago, pioneering neuroscientist Santiago Ramón y Cajal first suggested that the brain stores information by rearranging the connections, or synapses, between neurons.

Since then, neuroscientists have attempted to understand the physical changes associated with memory formation. But visualizing and mapping synapses is challenging to do. For one, synapses are very small and tightly packed together. They’re roughly 10 billion times smaller than the smallest object a standard clinical MRI can visualize. Furthermore, there are approximately 1 billion synapses in the mouse brains researchers often use to study brain function, and they’re all the same opaque to translucent color as the tissue surrounding them.

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Farmers struggling to adapt to rising temperatures in tropical regions can unleash the benefits of natural cooling, alongside a host of other wins, simply by dotting more trees across their pasturelands. For the first time, a study led by the University of Washington puts tangible numbers to the cooling effects of this practice.

Researchers at the UW and The Nature Conservancy, along with Duke University, the University of California San Diego and Stony Brook University Hospital, find that adding trees to pastureland, technically known as silvopasture, can cool local temperatures by up to 2.4 C (4.3 F) for every 10 metric tons of woody material added per hectare (about 4 tons per acre) depending on the density of trees, while also delivering a range of other benefits for humans and wildlife.

The paper was published Feb. 4 in Nature Communications.

Can you crumple up two sheets of paper the exact same way? Probably not—the very flexibility that lets flexible structures from paper to biopolymers and membranes undergo many types of large deformations makes them notoriously difficult to control. Researchers from the Georgia Institute of Technology, Universiteit van Amsterdam, and Universiteit Leiden have shed new light on this fundamental challenge, demonstrating that new physical theories provide precise predictions of the deformations of certain structures, as recently published in Nature Communications.

In the paper, Michael Czajkowski and D. Zeb Rocklin from Georgia Tech, Corentin Coulais from Universiteit van Amsterdam, and Martin van Hecke of AMOLF and Universiteit Leiden approach a highly studied exotic elastic material, uncover an intuitive geometrical description of the pronounced—or nonlinear—soft deformations, and show how to activate any of these deformations on-demand with minimal inputs. This new theory reveals that a flexible mechanical structure is governed by some of the same math as electromagnetic waves, phase transitions, and even black holes.

“So many other systems struggle with how to be strong and solid in some ways but flexible and compliant in others, from the human body and micro-organisms to clothing and industrial robots,” said Rocklin. “These structures solve that problem in an incredibly elegant way that permits a single folding mechanism to generate a wide family of deformations. We’ve shown that a single folding mode can transform a structure into an infinite family of shapes.”

A new set of molecular building blocks aims to make complex chemistry as simple and accessible as a toy construction kit.

Researchers at the University of Illinois Urbana-Champaign and collaborators at Revolution Medicines Inc. developed a new class of chemical building blocks that simply snap together to form 3D molecules with complex twists and turns, and an automated machine to assemble the blocks like a 3D printer for molecules.

This automation could allow chemists and nonchemists alike to develop new pharmaceuticals, materials, diagnostic probes, catalysts, perfumes, sweeteners and more, said study leader Dr. Martin D. Burke, a professor of chemistry at Illinois and a member of the Carle Illinois College of Medicine, as well as a medical doctor. The researchers reported their findings in the journal Nature.

Chula Medicine has successfully invented RED-GEMs (REjuvenating DNA by GEnomic Stability Molecules) that can reverse aging in lab animals. With human trials targeted within two years, the medical breakthrough is aimed to treat various age-related conditions and illnesses and bring back youthfulness in this aging society.

Measuring Human Biology in Action, To Cure, Prevent Or Manage All Diseases — Dr. Stephani Otte, Ph.D., Science Program Officer, Imaging, Chan Zuckerberg Initiative.

Dr. Stephani Otte, Ph.D is Science Program Officer, Imaging, at the Chan Zuckerberg Initiative (https://chanzuckerberg.com/), who leads the organization’s Imaging program and is focused on the creation, dissemination, optimization, and standardization of transformative imaging technologies.

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Michel Roccati, 30, was one of three paralyzed men to test a prototype of a spinal implant modified to help them move their limbs.

Some algorithms can now compose a 3D scene from 2D images—creating possibilities in video games, robotics, and autonomous driving.

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CHICAGO, Feb 4 (Reuters) — A study in monkeys pitting the current Moderna Inc (MRNA.O) COVID-19 booster against an Omicron-specific booster showed no significant differences in protection, suggesting an Omicron-specific booster may not be needed, U.S. government researchers reported on Friday.

The study involved monkeys vaccinated with two doses of Moderna’s vaccine who were dosed nine months later with either the conventional Moderna booster or one specifically targeting the Omicron variant.

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Pioneering global generic medicine access to improve and extend people’s lives — keren haruvi snir-president, sandoz US, head of north america.

Keren Haruvi is President of Sandoz US and Head of their North America business (https://www.novartis.us/about-us/our-leadership/us-country-l…n-haruvi).

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