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New data-driven algorithm can forecast the mortality risk for certain cardiac surgery patients

A machine learning-based method developed by a Mount Sinai research team allows medical facilities to forecast the mortality risk for certain cardiac surgery patients. The new method is the first institution-specific model for determining the risk of a cardiac patient before surgery and was developed using vast amounts of Electronic Health Data (EHR).

Comparing the data-driven approach to the current population-derived models reveals a considerable performance improvement.

Researchers Invent E-skin That ‘Talks’ to the Brain

Summary: Researchers have developed an artificial electronic skin (e-skin) capable of converting sensory inputs into electrical signals that the brain can interpret. This skin-like material incorporates soft integrated circuits and boasts a variety of sensory abilities, including temperature and pressure detection.

This advance could facilitate the creation of prosthetic limbs with sensory feedback or advanced medical devices. The e-skin operates at a low voltage and can endure continuous stretching without losing its electrical properties.

Quantum Biology Could Revolutionize Our Understanding of How Life Works

In my work, I build instruments to study and control the quantum properties of small things like electrons. In the same way that electrons have mass and charge, they also have a quantum property called spin. Spin defines how the electrons interact with a magnetic field, in the same way that charge defines how electrons interact with an electric field. The quantum experiments I have been building since graduate school, and now in my own lab, aim to apply tailored magnetic fields to change the spins of particular electrons.

Research has demonstrated that many physiological processes are influenced by weak magnetic fields. These processes include stem cell development and maturation, cell proliferation rates, genetic material repair, and countless others. These physiological responses to magnetic fields are consistent with chemical reactions that depend on the spin of particular electrons within molecules. Applying a weak magnetic field to change electron spins can thus effectively control a chemical reaction’s final products, with important physiological consequences.

Currently, a lack of understanding of how such processes work at the nanoscale level prevents researchers from determining exactly what strength and frequency of magnetic fields cause specific chemical reactions in cells. Current cell phone, wearable, and miniaturization technologies are already sufficient to produce tailored, weak magnetic fields that change physiology, both for good and for bad. The missing piece of the puzzle is, hence, a “deterministic codebook” of how to map quantum causes to physiological outcomes.

Researchers report technique to fabricate nanosheets in one minute

A research group led by Professor Minoru Osada (he, him) and postdoctoral researcher Yue Shi (she, her) at the Institute for Future Materials and Systems (IMaSS), Nagoya University in Japan, has developed a new technology to fabricate nanosheets, thin films of two-dimensional materials a couple of nanometers thick, in about one minute.

This technology enables the formation of high-quality, large films with a single click without the need for specialized knowledge or technology. Their findings are expected to contribute to developing the industrial manufacturing process for various types of nanosheet devices. The study was published in ACS Applied Materials & Interfaces.

Nanosheets have a thickness that is measured in nanometers. Nanometers are so thin that the sheets cannot be seen from the side with the naked eye. They have potential uses in several different fields, including electronics, catalysis, energy storage, and biomedicine. Those made from graphene and inorganic nanosheets are being tested for use in a range of devices, from to sensors and batteries, because they have electrical, transparency, and heat-resistance functions different from those of conventional bulk materials.

Researchers Discover New Way To Fight the Aging Process

Researchers at the University of Cologne have discovered a protein complex, called DREAM, that inhibits DNA repair mechanisms in human, mouse, and nematode cells, thereby contributing to aging and disease. They successfully suppressed the DREAM complex with a pharmaceutical agent, boosting the cells’ resilience to DNA damage, and suggesting potential new treatments for aging and cancer, although further research is needed.

Researchers at the University of Cologne have found that a protein complex impedes the repair of genomic damage in human cells, mice, and the nematode Caenorhabditis elegans. Furthermore, they were able to successfully obstruct this complex with a pharmaceutical agent for the first time.

When we suppress the so-called DREAM complex in body cells, various repair mechanisms kick in, making these cells extremely resilient towards all kinds of DNA.

International team creates first chimeric human-monkey embryos

Year 2022


Experiments such as this one cannot be funded with federal research dollars, though they break no U.S. laws. The work was conducted in China, not because it was illegal in the United States, the researchers said, but because the monkey embryos, which are difficult to procure and expensive, were available there. The experiment used a total of 150 embryos, which were obtained without harming the monkeys, “just like in the IVF procedure,” Tan said.

But such experiments, which combine human cells with those of animals, are nevertheless controversial. This work, and other work by Izpisua Belmonte, has moved so rapidly, bioethicists have had trouble keeping up.

“The complicated thing is that we need better models of human disease, but the better those models are, the closer they bring us to the ethical issues we were trying to avoid by not doing experiments in humans,” Farahany said. “Remarkable steps forward require urgent public engagement.”

Scientists in China have grown deer antlers on mice using stem cells:

They identified a new type of stem cell, which enables deer to regenerate their antlers year after year.

When transplanted into mice, it took just 45 days for them to grow antler-like bumps containing cartilage and bone.

This early research could potentially give us a better way to repair skeletal injuries — and maybe even help us to regrow our own limbs one day: https://www.freethink.com/science/deer-antlers-regeneration.

📸: Credit: T. Qin et al. / Science Freethink.

Researchers are stuffing drones into taxidermy birds to make them seem more ‘natural’

Researchers have engineered a robotic lionfish with synthetic arteries, similar to those found in a human’s circulatory system. The fish “blood” that runs through it serves as both the robot’s power source and controls its movement. The findings, published Wednesday in Nature, may propel the new wave of soft robots, in which inventors seek to improve lifelike automated machines for human connection.


It’s a bird, it’s a plane, it’s… sort of both, actually. And its designers think animals won’t notice the difference.

A bit long, but a good read

Ago when I was a kid in college my friend Eric got me into many things. We played music together and used a Kurzweil Keyboard, and a bunch of weird stuff. We had an ADAT hooked up to the Kurzweil with fiber optic cables. I had Roland keyboards & Drum machines but I loved the Kurzweil. He started teaching me many things because he was really smart. I was studying psychology so he loaned me his DSMIV and books on Industrial Organiza… See more.

A bit long, but a good read. About 20 years ago when I was a kid in college my friend Eric got me into many things. We played music together and used a Kurzweil Keyboard, and a bunch of weird stuff. We had an ADAT hooked up to the Kurzweil with fiber optic cables. I had Roland keyboards & Drum machines but I loved the Kurzweil. He started teaching me many things because he was really smart. I was studying psychology so he loaned me his DSMIV and books on Industrial Organizational Psychology. He then told me about other books like “Society of Mind”(Marvin Minsky), “Age of Intelligent Machine” (Ray Kurzweil), Engines of Creation (K Eric Drexler), of course Richard Feynman, and many more. I dreamed of that technology and kept reading more. In the 2000’s Drexler and Feynman’s visions became a paradign and applications started rolling out, and now nanotechnology is applied to most everything we know. We are now at the second paradigm where we see the visions of Minsky/McCarthy, Kurzweil and others becoming easily available applications. As a Child I watched the Jetsons & Srar Trek and now with flying cars it’s not if, but when. Space travel is already here. All these technologies will transform global societies, but we must all focus on investing more in the advancement of society than the destruction of it. Many of the things we now invision in our minds we may see in 10 years. People think saving your consciousness & longevity is impossible, but I don’t. Some even thought that regenerating tissue and organs is impossible, but we can do that now. Now people keep saying, “This ancient turtle died, this rhino died (I hear that all the time in Kenya), this elephant died, but I say okay it’s not cool, but what can we salvage from it to bring the species back with advances in technology later? Do we use cryogenics? How do we save the genetic material? Technology can be used in so many ways. Every Day Lifeboat posts feats many do not know. If more people on earth had such a focus, as opposed to dumbed down entertainment like The Kardashians for instance, we would be living in a much better world with more people proposing more ideas and collaborations. I always say we are moving in the wrong way in the evolutionary process, and it is a bit telling that some phones are smarter than many people. I you add ChatGPT. We have so much advanced technology and science, yet we can’t even fight cancer. It took decades for people to learn the importance of diet in HIV treatment. However, Ray Kurzweil has for decades talked about the importance of diet for longevity. Just the other day it was published that processed foods affect cognitive function. Before that it was released processed foods cause cancer. We must change, and go in the right way of evolution to the Singularity another paradigm shift and cooperarion, instead of backwards to a barbaric age of conflict and greed. Always share your knowledge and I thank all who do share in this group. More should share as well, and Lifeboat should use more platforms to reach more people.

Tensor Holography MIT Student creates AI learning advancing Holograms

From 2021

A new method called tensor holography could enable the creation of holograms for virtual reality, 3D printing, medical imaging, and more — and it can run on a smartphone.

YouTube.


PhD student from MIT’s Department of Electrical Engineering and Computer Science Liang Shi said people once believed that with the existing consumer-grade computer hardware, it’s impossible to do real-time 3D holograms. It’s going to take decades before it would be viable, but he figured out a way to cut that time.

Holographic image is not just made up in the movies, it’s being created as we speak. Shi’s team took a different approach from what was first developed in holograms, where laser beam would split, half the beam is used to illuminate the subject and the other half used as a reference for the light waves phase.