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Aug 30, 2024

Electrochemical meta-C–H sulfonylation of pyridines with nucleophilic sulfinates

Posted by in category: chemistry

Direct meta-selective C–H functionalization of pyridines is of paramount importance, but such reactions remain limited and highly challenging. Here, the authors report an electrochemical methodology in which nucleophilic sulfinates allow meta-sulfonylation of pyridines through a redox-neutral dearomatization-rearomatization strategy.

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