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Apr 15, 2024

On World Parkinson’s Day, a New Theory Emerges on the Disease’s Origins and Spread

Posted by in categories: biotech/medical, chemistry, food, health, neuroscience

A new hypothesis paper appearing in the Journal of Parkinson’s Disease on World Parkinson’s Day unites the brain-and body-first models with some of the likely causes of the disease–environmental toxicants that are either inhaled or ingested.


Pointing to a growing body of research linking environmental exposure to Parkinson’s disease, the authors believe the new models may enable the scientific community to connect specific exposures to specific forms of the disease. This effort will be aided by increasing public awareness of the adverse health effects of many chemicals in our environment. The authors conclude that their hypothesis “may explain many of the mysteries of Parkinson’s disease and open the door toward the ultimate goal–prevention.”

In addition to Parkinson’s, these models of environmental exposure may advance understanding of how toxicants contribute to other brain disorders, including autism in children, ALS in adults, and Alzheimer’s in seniors. Dorsey and his colleagues at the University of Rochester have organized a symposium on the Brain and the Environment in Washington, DC, on May 20 that will examine the role toxicants in our food, water, and air are playing in all these brain diseases.

Additional authors of the hypothesis paper include Briana De Miranda, PhD, with the University of Alabama at Birmingham, and Jacob Horsager, MD, PhD, with Aarhus University Hospital in Denmark.

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