May 9, 2024
Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome and intestinal immune homeostasis in mice
Posted by Shubham Ghosh Roy in category: biotech/medical
News: Skin injuries can modify the gut microbiome, according to a NIAMSfunded study led by UC San Diego.
Read the OpenAccess paper via Nature Portfolio.
The microbial community in the intestine can affect other organs such as the skin but it is not clear if the opposite can occur. Here the authors show that skin wounding affects the microbial composition of the intestinal flora which then enhances DSS induced colitis and intestinal inflammation.