Lifeboat Foundation

A team led by NCI researchers has developed an artificial intelligence (AI) tool that uses data from individual cells inside tumors to predict whether a person’s cancer will respond to a specific drug. Learn more about how these findings hold promise for optimally matching cancer drugs to patients:

Precision oncology, in which doctors choose cancer treatment options based on the underlying molecular or genetic signature of individual tumors, has come a long way. The Food and Drug Administration has approved a growing number of tests that look for specific genetic changes that drive cancer growth to match patients to targeted treatments. The NCI-MATCH trial, supported by the National Cancer Institute, in which participants with advanced or rare cancer had their tumors sequenced in search of genetic changes that matched them to a treatment, has also suggested benefits for guiding treatment through genetic sequencing. But there remains a need to better predict treatment responses for people with cancer.

A promising approach is to analyze a tumor’s RNA in addition to its DNA. The idea is to not only better understand underlying genetic changes, but also learn how those changes impact gene activity as measured by RNA sequencing data. A recent study introduces an artificial intelligence (AI)-driven tool, dubbed PERCEPTION (PERsonalized single-Cell Expression-based Planning for Treatments In ONcology), developed by an NIH-led team to do just this.¹ This proof-of-concept study, published in Nature Cancer, shows that it’s possible to fine-tune predictions of a patient’s treatment responses from bulk RNA data by zeroing in on what’s happening inside single cells.

Continue reading “AI Tool Using Single-Cell Data Has Promise for Optimally Matching Cancer Drugs to Patients” »

Influencer makes AI clone of herself. But it turns out badly.

Caryn Marjorie is a social media influencer whose content has more than a billion views per month on Snapchat. She posts regularly, featuring everyday moments, travel memories, and selfies. Many of her followers are men, attracted by her girl-next-door aesthetic.

In 2023, Marjorie released a “digital version” of herself. Fans could chat with CarynAI for US$1 per minute – and in the first week alone they spent US$70,000 doing just that.

Continue reading “An influencer’s AI clone started offering fans ‘mind-blowing sexual experiences’ without her knowledge” »

Stanford’s new tiny, cheap laser:

Researchers have achieved a potentially groundbreaking innovation in laser technology by developing a titanium-sapphire (Ti: sapphire) laser on a chip. This new prototype is dramatically smaller, more efficient, and less expensive than its predecessors, marking a significant leap forward with a technology that has broad applications in industry, medicine, and beyond.

Ti: sapphire lasers are known for their unmatched performance in quantum optics, spectroscopy, and neuroscience due to their wide gain bandwidth and ultrafast light pulses. However, their bulky size and high cost have limited their widespread adoption. Traditional Ti: sapphire lasers occupy cubic feet in volume and can cost hundreds of thousands of dollars, in addition to requiring high-powered lasers costing $30,000 each to feed it the energy it needs to operate.

Continue reading “Researchers develop tiny, cost-effective Ti laser that fits on a chip” »

Receiver blocks interference early:

MIT researchers also state that the interference-blocking components can be switched on and off as needed to conserve energy.

Степень возмущенности магнитного поля планеты достигла уровня G4.

In the creepiest video of 2024, a scientist explains how his system, Cognify, could ‘fix’ prisoners by implanting AI-generated artificial memories in their brains. And it somehow gets weirder.

Astronauts Butch Wilmore and Suni Williams blasted off on June 5 — the start of a test flight that was expected to last just a week or so.

A stuck lens cover had prevented SHERLOC from focusing on targets.

Starlink satellites were deployed by SpaceX. Watch multiple views captured by cameras aboard the Falcon 9 rocket second stage. Credit: Space.com | footage courtesy: SpaceX | edited by Steve Spaleta Music: New Age Solitude by Philip Ayers / courtesy of Epidemic Sound.