Lifeboat Foundation

Construction workers have finished the excavation of the huge caverns that will house the international Deep Underground Neutrino Experiment. While engineers and technicians are preparing for the installation of the gigantic neutrino detectors into these caverns a mile underground, scientists around the world are working to optimize DUNE’s particle detector technology.

Adding or removing neutrons from an atomic nucleus leads to changes in the size of the nucleus. This in turn causes tiny changes in the energy levels of the atom’s electrons, known as isotope shifts. Scientists can use precision measurements of these energy shifts to measure the radius of the nucleus of an isotope.

Light technology is at the heart of many cutting-edge innovations, from high-speed internet to advanced medical imaging. However, transmitting light through challenging environments, such as turbulent atmospheres or deformed optical systems, has always posed a significant hurdle. These complexities can distort and disrupt the light field, making it difficult to achieve clear and reliable results. Scientists have long sought ways to overcome these limitations, and a new breakthrough may hold the key to advancing practical applications.

Key to winning a cricket match is tricking the other team’s batters—no small feat, as bowlers bowl cricket balls nearly 100 miles per hour. In recent years, a bowling technique that has become popular involves keeping the arm almost entirely horizontal during delivery, notably used by Sri Lankan stars Lasith Malinga and Matheesha Pathirana. The aerodynamics of such deliveries have perplexed sports physicists.

Researchers at the University of Houston unveiled an advancement in X-ray imaging technology that could provide significant improvements in medical diagnostics, materials and industrial imaging, transportation security and other applications.

An international team of astronomers has reported the discovery of a new brown dwarf, which received designation TOI-2490 b. The newfound object is about 74 times more massive than Jupiter and orbits a sun-like star on a highly eccentric orbit. The finding was detailed in a paper published August 8 on the pre-print server arXiv.

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That the universe began seems astonishing. What brought it about? What forces were involved? How did the laws of nature generate the vast expanse of billions of galaxies of billions of stars and planets in the structures that we see today? What new physics was involved? What more must we learn?

Continue reading “Alexander Vilenkin — Why Did Our Universe Begin?” »

Bracha et al.

Toxoplasma gondii culture and maintenance.

Type I RH and type II Pru and ME49 strain T. gondii were grown in HFF in high-glucose Dulbecco’s modified Eagle’s medium (DMEM) supplemented with 4 mM l-glutamine, 10% fetal bovine serum (FBS) and 1% penicillin/streptomycin or 20 μg ml⁻¹ gentamicin antibiotics (‘complete DMEM’) at 37 °C with 5% CO₂. Cultures were monitored daily and T. gondii were passaged by transferring 1–3 drops (20–100 μl) of the supernatant of a lysed dish (containing extracellular parasites) into a fresh dish with confluent HFF cells. Type I RH and type II Pru strains were validated by PCR–restriction-fragment length polymorphism (primers described in Supplementary Table 1)⁸¹ or by passage into Cre Reporter cell lines to confirm Cre recombination as previously described¹⁶.

Continue reading “Engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons” »

48 likes, — designdelulu on May 23, 2024: ‘Jensen Huang says designing computer chips and writing software can no longer be done without AI and he wants to turn NVIDIA into one giant AI’