Lifeboat Foundation

This video explains transition vs transversion mutations.

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Altered dystrophin expression was found in some tumors and recent studies identified a developmental onset of Duchenne muscular dystrophy (DMD). Given that embryogenesis and carcinogenesis share many mechanisms, we analyzed a broad spectrum of tumors to establish whether dystrophin alteration evokes related outcomes. Transcriptomic, proteomic, and mutation datasets from fifty tumor tissues and matching controls (10,894 samples) and 140 corresponding tumor cell lines were analyzed. Interestingly, dystrophin transcripts and protein expression were found widespread across healthy tissues and at housekeeping gene levels. In 80% of tumors, DMD expression was reduced due to transcriptional downregulation and not somatic mutations. The full-length transcript encoding Dp427 was decreased in 68% of tumors, while Dp71 variants showed variability of expression.

In 1960, visionary physicist Freeman Dyson proposed that an advanced alien civilization would someday quit fooling around with kindergarten-level stuff like wind turbines and nuclear reactors and finally go big, completely enclosing their home star to capture as much solar energy as they possibly could. They would then go on to use that enormous amount of energy to mine bitcoin, make funny videos on social media, delve into the deepest mysteries of the Universe, and enjoy the bounties of their energy-rich civilization.

But what if the alien civilization was… us? What if we decided to build a Dyson sphere around our sun? Could we do it? How much energy would it cost us to rearrange our solar system, and how long would it take to get our investment back? Before we put too much thought into whether humanity is capable of this amazing feat, even theoretically, we should decide if it’s worth the effort. Can we actually achieve a net gain in energy by building a Dyson sphere?

A killer plant fungus infected a human and caused flu-like symptoms in what researchers say is a world-first case.

Chondrostereum purpureum causes silver leaf disease in flora, most commonly in species of rose.

Spread by airborne spores, it is named such because it gradually turns leaves silver — and is often fatal.

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Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey. Some aspects of how these cephalopods become reversibly transparent are still “unclear,” largely because researchers can’t culture cephalopod skin cells in the lab.

Today, however, researchers report that they have replicated the tunable transparency of some squid skin cells in mammalian cells, which can be cultured. The work could not only shed light on basic squid biology, but also lead to better ways to image many cell types.

The researchers will present their results at the spring meeting of the American Chemical Society (ACS). ACS Spring 2023 is a hybrid meeting being held virtually and in-person March 26–30, and features more than 10,000 presentations on a wide range of science topics.

The non-profit said powerful AI systems should only be developed “once we are confident that their effects will be positive and their risks will be manageable.” It cited potential risks to humanity and society, including the spread of misinformation and widespread automation of jobs.

The letter urged AI companies to create and implement a set of shared safety protocols for AI development, which would be overseen by independent experts.

Apple cofounder Steve Wozniak, Stability AI CEO Emad Mostaque, researchers at Alphabet’s AI lab DeepMind, and notable AI professors have also signed the letter. At the time of publication, OpenAI CEO Sam Altman had not added his signature.

In my latest interview, I answer some questions on the fascinating topic of synthetic telepathy. Recently, the concept of synthetic telepathy has gained increasing attention from both the scientific community and the general public. The ability to communicate with others using only our thoughts may sound like something straight out of science fiction, but recent advancements in neuroscience and technology have brought us closer to making this a reality.

#SyntheticTelepathy #neurotechnology #braincomputerinterface #BCI #cybernetics #brainhacking #mindcontrol #nanocybernetics

In recent years, the concept of synthetic telepathy has gained increasing attention from both the scientific community and the general public. The ability to communicate with others using only our thoughts may sound like something straight out of science fiction, but recent advancements in neuroscience and technology have brought us closer to making this a reality. Join us for an exclusive interview with futurist and evolutionary cyberneticist Alex M. Vikoulov, as he shares his expertise on the fascinating topic of synthetic telepathy. Speaking with news reporter Blanca Elena Reyes, Vikoulov will delve into the workings of this cutting-edge technology and discuss its potential applications for the future.

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OAKLAND, California, March 28 (Reuters) — Artificial intelligence chip startup Cerebras Systems on Tuesday said it released open source ChatGPT-like models for the research and business community to use for free in an effort to foster more collaboration.

Silicon Valley-based Cerebras released seven models all trained on its AI supercomputer called Andromeda, including smaller 111 million parameter language models to a larger 13 billion parameter model.

“There is a big movement to close what has been open sourced in AI…it’s not surprising as there’s now huge money in it,” said Andrew Feldman, founder and CEO of Cerebras. “The excitement in the community, the progress we’ve made, has been in large part because it’s been so open.”

Energy production in nature is the responsibility of mitochondria and chloroplasts, and is crucial for fabricating sustainable, synthetic cells in the lab. Mitochondria are “the powerhouses of the cell,” but are also one of the most complex intracellular components to replicate artificially.

In Biophysics Reviews, by AIP Publishing, researchers from Sogang University in South Korea and the Harbin Institute of Technology in China identified the most promising advancements and greatest challenges of artificial mitochondria and chloroplasts.

“If scientists can create artificial mitochondria and chloroplasts, we could potentially develop synthetic cells that can generate energy and synthesize molecules autonomously. This would pave the way for the creation of entirely new organisms or biomaterials,” author Kwanwoo Shin said.