Lifeboat Foundation

Summary: A recent study explored the link between cadmium exposure and cognitive decline, finding that higher cadmium levels may be associated with thinking and memory problems in white people. The study followed 2,172 people over 10 years, with results showing no association overall but revealing a possible link when analyzing Black and white participants separately.

White participants with high cadmium levels were twice as likely to develop cognitive impairment compared to those with lower levels. However, no similar association was found in Black participants, and further research is needed to confirm these findings.

Summary: Sound stimulation can manipulate brain waves during REM sleep, a stage crucial for memory and cognition. Using advanced technology, researchers were able to increase the frequency of brain oscillations that slow down in dementia patients, potentially improving memory functions.

The non-invasive technique could pave the way for innovative treatments for dementia by targeting brain activity during sleep. This approach offers hope for enhancing memory and cognition with minimal disruption to patients’ lives.

Observing anything and everything within the human brain, no matter how large or small, while it is fully intact has been an out-of-reach dream of neuroscience for decades.

Three new innovations from an MIT-based team enables high-resolution, high-throughput imaging of human brain tissue at a full range of scales, and mapping connectivity of neurons at single-cell resolution.

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A collaboration of a neurologist, a computer scientist, and a philosopher has just put forward a new theory of consciousness. It is based on the idea of causal models. The authors claim boldly that their idea solves the hard problem of consciousness and explains why zombies don’t exist in nature. Really? I’ve had a look.

Continue reading “New Theory of Consciousness Explains Why Zombies Don’t Exist” »

We tackle the hard problem of consciousness taking the naturally-selected, self-organising, embodied organism as our starting point. We provide a mathematical formalism describing how biological systems self-organise to hierarchically interpret unlabelled sensory information according to valence and specific needs. Such interpretations imply behavioural policies which can only be differentiated from each other by the qualitative aspect of information processing. Selection pressures favour systems that can intervene in the world to achieve homeostatic and reproductive goals. Quality is a property arising in such systems to link cause to affect to motivate real world interventions. This produces a range of qualitative classifiers (interoceptive and exteroceptive) that motivate specific actions and determine priorities and preferences.

Summary: Neural stem cells, which create new neurons in the brain, become less active with age due to elevated glucose levels. Researchers found that by knocking out the glucose transporter gene GLUT4 in older mice, they could significantly increase the production of new neurons.

This discovery opens up potential pathways for both genetic and behavioral interventions to stimulate brain repair, including the possibility of a low-carbohydrate diet. The findings could help treat neurodegenerative diseases and aid in brain recovery after injury.

Patients with certain mental disorders, including schizophrenia, often hear voices in the absence of sound.

Auditory hallucinations are likely the result of abnormalities in two brain processes: a broken corollary discharge that fails to suppress self-generated sounds, and a noisy efference copy that makes the brain hear these sounds more intensely than it should. That is the conclusion of a study published October 3 in the open-access journal PLOS Biology by Xing Tian, of New York University Shanghai, China, and colleagues.

In the new study, researchers carried out electroencephalogram (EEG) experiments measuring the brain waves of 20 patients diagnosed with schizophrenia with auditory hallucinations and 20 patients diagnosed with schizophrenia who had never experienced such hallucinations.

🧠 Neuromodulation through the eyes 👀

Neuroplasticity, also known as neural plasticity or brain plasticity, is a process that involves adaptive structural and functional changes to the brain.

Founded and directed by Deborah Zelinsky, O.D., F.N.O.R.A., F.C.O.V.D.

Continue reading “The Z-Bell℠ Test: A Breakthrough in Eye-Ear Testing” »

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Imagine trying to understand the brain’s activity over time—an incredibly complex and dynamic process that happens at different speeds.

To solve this problem, we developed a pipeline called UnitMatch, which operates after spike sorting. Before applying UnitMatch, the user spike sorts each recording independently using their preferred algorithm. UnitMatch then deploys a naive Bayes classifier on the units’ average waveform in each recording and tracks units across recordings, assigning a probability to each match.

Continue reading “Tracking neurons across days with high-density probes” »