Lifeboat Foundation

The US population is almost not growing.

The U.S. population grew at the slowest rate on record in 2021 as slowing migration, an aging population and low birth rates were exacerbated by the Covid pandemic, U.S. Census Bureau data released Tuesday show.

The population expanded by just 0.1% or 392,665 people this year, a smaller increase than during the influenza pandemic and World War I in the early years of the last century. It’s also the first time since 1937 that the population has expanded by less than 1 million.

Continue reading “U.S. Population Grows at Lowest Rate on Record During Pandemic” »

A year in review.

This video is sponsored by ResearchHub — https://www.researchhub.com/?ref=eleanorsheeky.

Continue reading “This years biggest breakthroughs in longevity science!!” »

The rich world is ageing fast. How can societies afford the looming costs of caring for their growing elderly populations? film supported by @Mission Winnow.

00:00 The wealthy world is ageing.
01:17 Japan’s elderly population.
02:11 The problems of an ageing world.
04:01 Reinventing old age.
05:48 Unlocking the potential of older years.
07:09 Reforming social care.
08:20 A community-based approach.
11:08 A fundamental shift is needed.

Continue reading “The World Ahead: the true costs of ageing | The Economist” »

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Papers referenced in the video:
Ergothioneine exhibits longevity-extension effect in Drosophila melanogaster via regulation of cholinergic neurotransmission, tyrosine metabolism, and fatty acid oxidation.
https://pubmed.ncbi.nlm.nih.gov/34877949/

Continue reading “Ergothioneine Extends Lifespan (in flies)” »

Few individuals write about issues that impact human survival. Fewer still win multiple literary awards for writing science fiction novels. Hardly anyone joins a major corporation as chief futurist. Neal Stephenson can be credited for doing all three.

Writer, academician, video game designer and technology consultant are just some of the things Neal is famous for. He has authored historical epic novels ‘Cryptonomicon’ and ‘The Baroque Cycle;’ science fiction novels ‘The Diamond Age’ and ‘Anathem;’ contemporary thrillers ‘Zodiac’ and ‘REAMDE;’ and science fiction epic ‘Seveneves,’ among others.

His “Snow Crash” published in 1992 preceded ” The Matrix” series and introduced the concept of “The Metaverse”. Yes, Neal Stephenson coined the term. And his 1994 “Interface” preceded NeuraLink by over 20 years!

Continue reading “The Original Inventor Of ‘Metaverse’ On Technology, Life, And Books: Interview With Neal Stephenson” »

Business Enquiries ► Lorenzovareseaziendale@gmail.com.
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Undoubtedly the fear of death, encoded in our DNA to improve our chances of survival, is one of the least pleasant characteristics we are forced to live with. The idea that our life must have an end and then there is nothingness is not at all attractive, so it is not surprising that in the course of his history man has imagined countless ways to circumvent death.
Immortality (or eternal life) is the concept of surviving forever or for an indefinite period of time, without facing death or overcoming death itself.

Immortality can be intended in two main meanings, physical and spiritual. Physical immortality is generally conceived as the endless existence of the mind from a physical source, such as a brain or a computer. Spiritual immortality is generally conceived as the endless existence of an individual after physical death.

Continue reading “The Future Technology To Become Immortal” »

They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces. Thus, how long we remain healthy also depends on how long the T cells survive. Researchers at the University of Basel have now uncovered a previously unknown signaling pathway essential for T cell viability.

Like human beings, every cell in our body tries to ward off death as long as it can. This is particular true for a specific type of immune cells, called T-lymphocytes, or T cells for short. These cells keep viruses, bacteria, parasites and cancerous cells at bay. While T cell production is an active process in infants, children and young adults, it comes to a gradual stop upon aging, meaning that in order to maintain adequate immunity up to an old age, your T cells should better live as long as you.

How T cells manage to survive for such a long time, up to several decades in humans, has long remained unclear. In collaboration with scientists at the Department of Biomedicine and sciCORE, the Center for Scientific Computing of the University of Basel, Professor Jean Pieters’ research group at the Biozentrum has now revealed the existence of a hitherto unrecognized pathway promoting long-term survival of T cells. In Science Signaling they report that this signaling pathway, regulated by the protein coronin 1, is responsible for suppressing T cell death.

A good deal of evidence points to declining kidney function as a cause of declining cognitive function in aging. There are strong correlations between loss of kidney function and risk of dementia, for example. Correlation isn’t a smoking gun in matters of aging, however: it is possible for any one of the underlying forms of molecular damage that cause aging, or for intermediate consequences of that damage, to give rise to otherwise unrelated pathologies in different parts of the body. Those pathologies appear more often in people with greater amounts of that form of damage, and thus appear correlated.

Nonetheless, there are good reasons to think that kidney failure and its downstream consequences contribute meaningful to neurodegeneration, perhaps largely by degrading the function of the vascular system. Vascular aging can cause damage and dysfunction in brain tissue via numerous mechanisms, including the pressure damage of hypertension, similar damage resulting from an acceleration of atherosclerosis, failing to delivery sufficient nutrients and oxygen to the energy-hungry brain, and disruption of the blood-brain barrier, allowing inflammatory cells and molecules into the brain.

Interactions Between Kidney Function and Cerebrovascular Disease: Vessel Pathology That Fires Together Wires Together.

An experimental vaccine successfully eliminated aging cells from the bodies of mice, helping to prolong the rodents’ lives and reverse some signs of age-related disease. The researchers say the experiment is a step on the road to a similar vaccine for humans, but could it really work?