The Neuro-Network.
𝐇𝐨𝐰 ‘𝐃𝐨𝐫𝐦𝐚𝐧𝐭’ 𝐂𝐞𝐥𝐥𝐬 𝐈𝐧 𝐓𝐡𝐞 𝐀𝐠𝐢𝐧𝐠 𝐁𝐫𝐚𝐢𝐧 𝐂𝐨𝐧𝐭𝐫𝐢𝐛𝐮𝐭𝐞 𝐓𝐨 𝐂𝐨𝐠𝐧𝐢𝐭𝐢𝐯𝐞 𝐃𝐞𝐜𝐥𝐢𝐧𝐞
𝘾𝙤𝙜𝙣𝙞𝙩𝙞𝙫𝙚 𝙙𝙚𝙘𝙡𝙞𝙣𝙚 𝙖𝙣𝙙 𝙛𝙤𝙧𝙜𝙚𝙩𝙩𝙞𝙣𝙜 𝙩𝙝𝙞𝙣𝙜𝙨 𝙖𝙨 𝙬𝙚 𝙜𝙚𝙩 𝙤𝙡𝙙𝙚𝙧 𝙞𝙨 𝙖𝙡𝙢𝙤𝙨𝙩 𝙖 𝙧𝙞𝙜𝙝𝙩 𝙤𝙛 𝙥𝙖𝙨𝙨𝙖𝙜𝙚. 𝘼𝙡𝙡… See more.
Continue reading “How ‘Dormant’ Cells In The Aging Brain Contribute To Cognitive Decline” »
Accelerating Research To Prevent & Cure Disease — Dr. Kevin Perrott, Ph.D., Founder & CEO, OpenCures; Co-Founder & Treasurer, SENS Research Foundation
Dr. Kevin Perrott, Ph.D. is Founder and CEO, OpenCures (https://opencures.org/), Adjunct Professor, University of Alberta, Co-Founder and Advisor, Oisin Biotechnologies, President, of Global Healthspan Policy Institute, and Co-Founder and Treasurer, SENS Research Foundation.
Cam & Dowel Jig is a collection of preset jigs and various tools that are designed to help guide users through designing and constructing their own bespoke furniture.
If you didn’t pick up woodworking as a hobby during the quarantine, chances are you at least tried. In a perfect world, we’d have the know-how to pick up some tools, some pieces of wood, and design our living rooms with our own collection of bespoke furniture. Alas, this is no perfect world so we’ll need some shortcuts. Luckily, David Needham of Kingfisher Design Studio has us covered with an intuitive tool kit designed to streamline bespoke, DIY furniture-building projects.
Dr. Marvin Minsky — A.I. Pioneer & Mind Theorist. Professor of Media Arts and Sciences, MIT, Media Lab http://GF2045.com/speakers.
As soon as we understand how the human brain works, we should be able to make functional copies of our minds out of other materials. Given that everything is made of atoms, if you make a machine, in some sense it is made of the same kinds of materials as brains are made but organized either in very different ways or fundamentally the same ways.
A team of scientists at Tufts University and Harvard University “have brought us a step closer to the goal of regenerative medicine” by using a drug cocktail to regrow a frog’s amputated legs.
Peer-reviewed study: https://www.science.org/doi/10.1126/sciadv.abj2164
Scientists say they have been able to help frogs regrow their legs for the first time. The next step? Try the procedure on mammals.
As Jess Bezos becomes the latest billionaire to attempt to conquer ageing, Gemma Askham meets those on the front line of the quest to delay death.
He’s backing a new biotech company working on “cellular rejuvenation programming.”
It sure looks like Jeff Bezos has plans to cheat death.
The founder and former CEO of Amazon has reportedly made an investment in the freshly launched Altos Labs, a biotech startup focused on “cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine,” according to a January 19 press release. With $3 billion in backing on day one, Altos Labs has hit the ground running with what may be the single largest funding round for a biotech company, according to the Financial Times of London.
Continue reading “Jeff Bezos Is Paying for a Way to Make Humans Immortal” »
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Levine’s Biological age calculator is embedded as an Excel file in this link from my website:
https://michaellustgarten.com/2019/09/09/quantifying-biological-age/
Blood plasma, cellular reprogramming, endogenous.
You may have heard a lot of talk recently about cellular reprogramming, rejuvenation or even “rejuvenation programming”, but what does that all mean and what are the 3 main strategies that several researchers and companies (maybe Altos Labs) will be further investigating?
There is nothing inevitable about aging, or about its rate. Californian bristlecone pines are believed to live for 5,000 years, and there are long-lived mammalian creatures as well. Some marine creatures do not display any signs of aging at all, including hydra, jellyfish, planarian worms, and coral. Certain human cells have immortal characteristics too. When a woman gives birth, she produces a baby which is “new”. Her “germline” (reproduction-related) cells produce a child with no signs of age.
These and many other considerations combine with the unreasonable effectiveness of modern AI to lead some people to believe that significant advances in longevity are imminent. These advances probably cannot happen without the active participation of the wider pharmaceutical industry, and the acceptance by policy makers and regulators that aging is a disease, not just an unfortunate and inevitable component of the human condition. There is still considerable reluctance among major pharmaceutical companies to contemplate specific anti-aging therapeutic developments. But there are encouraging signs of this reluctance being challenged, especially at Novartis and AstraZeneca.
Beyond the pharma giants, Mellon reckons there are 255 companies which claim to be specifically targeting aging, of which 35 are listed on stock markets. But he thinks that only a minority of them are genuinely working to tackle aging, as opposed to one of the diseases it causes, like cancer, dementia, or heart disease. He likens the state of the longevity industry today to the internet industry of 20 years ago, when it was still in its dial-up phase, and downloading information (or, heaven forbid, images) was like sucking jelly through a straw. And although longevity will have such a massive impact on all of us that you might expect progress to be expedited, Mellon points out that the internet did not have to go through lengthy and expensive FDA trials at every step.
