Lifeboat Foundation

In the ever-evolving realm of microscopy, recent years have witnessed remarkable strides in both hardware and algorithms, propelling our ability to explore the infinitesimal wonders of life. However, the journey towards three-dimensional structured illumination microscopy (3DSIM) has been hampered by challenges arising from the speed and intricacy of polarization modulation.

Enter the high-speed modulation 3DSIM system “DMD-3DSIM,” combining digital display with super-resolution imaging, allowing scientists to see cellular structures in unprecedented detail.

As reported in Advanced Photonics Nexus, Professor Peng Xi’s team at Peking University developed this innovative setup around a digital micromirror device (DMD) and an electro-optic modulator (EOM). It tackles resolution challenges by significantly improving both lateral (side-to-side) and axial (top-to-bottom) resolution, for a 3D spatial resolution reportedly twice that achieved by traditional wide-field imaging techniques.

A mathematical historian at Trinity Wester University in Canada, has found use of a decimal point by a Venetian merchant 150 years before its first known use by German mathematician Christopher Clavius. In his paper published in the journal Historia Mathematica, Glen Van Brummelen describes how he found the evidence of decimal use in a volume called “Tabulae,” and its significance to the history of mathematics.

The invention of the decimal point led to the development of the decimal system, and that in turn made it easier for people working in multiple fields to calculate non-whole numbers (fractions) as easily as whole numbers. Prior to this new discovery, the earliest known use of the decimal point was by Christopher Clavius as he was creating astronomical tables—the resulting work was published in 1593.

The new discovery was made in a part of a manuscript written by Giovanni Bianchini in the 1440s—Van Brummelen was discussing a section of trigonometric tables with a colleague when he noticed some of the numbers included a dot in the middle. One example was 10.4, which Bianchini then multiplied by 8 in the same way as is done with modern mathematics. The finding shows that a decimal point to represent non-whole numbers occurred approximately 150 years earlier than previously thought by math historians.

A material coating, whose light refraction properties can be precisely switched between different states, has been developed by an interdisciplinary research team from the Chemistry and Physics departments at the University of Jena. The team, led by Felix Schacher, Sarah Walden, Purushottam Poudel, and Isabelle Staude, combined polymers that react to light with so-called metasurfaces.

This innovation has led to the creation of new optical components that could potentially be used in signal processing. Their findings have now been published in the journal ACS Nano.

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Quantum gravity has long baffled scientists. Now, a breakthrough discovery could change physics forever — and answer our biggest questions.

“This trial has changed the lives of people with mesothelioma, allowing us to live longer,” said one of the patients who benefited from the drug. The 80-year-old, who wished to remain anonymous, won compensation from his former employer after being exposed to asbestos in a factory in the 1970s.

He was given four months to live, but thanks to the trial is still alive five years later. “I have five grandchildren and two great-grandchildren now – I wouldn’t want to miss all that,” he said.

The breakthrough is significant, experts say, because mesothelioma has one of the lowest survival rates of any cancer. The new drug, ADI-PEG20 (pegargiminase), is the first of its kind to be successfully combined with chemotherapy in 20 years.

MIT engineers achieve a breakthrough in electronics with fully 3D-printed solenoids, revolutionizing manufacturing and democratizing access to technology.

MIT engineers pioneer 3D-printed solenoids, unlocking new possibilities in electronics manufacturing.

Science fiction writers have anticipated a variety of modern inventions, from cars to organ transplants. Some books barely seem like fiction.

North Carolina State University researchers have discovered a new welding method for composite metal foam (CMF), preserving its light, strong, and thermally insulating properties, vital for numerous applications.

Researchers at North Carolina State University have now identified a welding technique that can be used to join composite metal foam (CMF) components together without impairing the properties that make CMF desirable. CMFs hold promise for a wide array of applications because the pockets of air they contain make them light, strong and effective at insulating against high temperatures.

Characteristics and Challenges of CMF.