Lifeboat Foundation

Cutting calories significantly may not be an easy task for most, but it’s tied to a host of health benefits ranging from longer lifespan to a much lower chance of developing cancer, heart disease, diabetes and neurodegenerative conditions such as Alzheimer’s.

A new study from teams led by Scripps Research Professors Bruno Conti, Ph.D., and Gary Siuzdak, Ph.D., illuminates the critical role that body temperature plays in realizing these diet-induced health benefits. Through their findings, the scientists pave the way toward creating a medicinal compound that imitates the valuable effects of reduced body temperature.

Continue reading “Linking calorie restriction, body temperature and healthspan” »

The cruise line was already eschewing cruise staples like buffets, setting Virgin Voyages ahead of the pack.

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Cooking foods at temperatures higher than boiling produces advanced glycation end (AGE) products, which induce insulin resistance and inflammation, and shorten lifespan in mice. Similar data exists in humans for the effect of AGE products on insulin resistance and inflammation, and a higher dietary AGE product intake is associated with cancer in both men and women. Accordingly, reducing dietary AGE product intake may be an important strategy for improving health and increasing lifespan in people.

Since antiquity, cultures on nearly every continent have discovered that certain plant leaves, when chewed or brewed or rubbed on the body, could relieve diverse ailments, inspire hallucinations or, in higher dosages, even cause death. Today, pharmaceutical companies import these once-rare plants from specialized farms and extract their active chemical compounds to make drugs like scopolamine for relieving motion sickness and postoperative nausea, and atropine, to curb the drooling associated with Parkinson’s disease or help maintain cardiac function when intubating COVID-19 patients and placing them on ventilators.

Now, Stanford engineers are recreating these ancient remedies in a thoroughly modern way by genetically reprogramming the cellular machinery of a special strain of yeast, effectively transforming them into microscopic factories that convert sugars and amino acids into these folkloric drugs, in much the same way that brewers’ yeast can naturally convert sugars into alcohol.

Low-temperature plasmas offer promise for applications in medicine, water purification, agriculture, pollutant removal, nanomaterial synthesis and more. Yet making these plasmas by conventional methods takes several thousand volts of electricity, says David Go, an aerospace and mechanical engineer at the University of Notre Dame. That limits their use outside high-voltage power settings.

In work supported by the U.S. National Science Foundation, Go and a team of researchers conducted research that explores making plasma devices that can be operated without electrical power—they need only human or mechanical energy.

Their paper in Applied Physics Letters introduces a strategy the scientists call “energy-conversion plasma” as an alternative to producing “transient spark” discharges without the need for a very high-voltage power supply.

But the question a lot of us in Australia might have is, when there are plenty of other protein options, why should we bother eating insects?

Insects are delicious and nutritious and can be grown in shipping containers in the middle of cities and towns. Is it time Australians joined the 2 billion people around the world who eat insects daily?

These plants have evolved to absorb metal from the soil via Seeker.

Rabia Nusrat, an environmental engineering student, Global UGRAD alumni, in her final year at University of Engineering and Technology, UET, Lahore, Pakistan and the first ideaXme public interviewer, interviews Shayan Sohail Sarwar, Forbes 30 Under 30 Asia Innovator and Chief Technology Officer PakVitae.

PakVitae:

Continue reading “Forbes 30 under 30 Asia Innovators 2020 from Pakistan Create PakVitae for the World” »

In a recent study conducted in mice, researchers became one step closer to that understanding, discovering that exercise actually strengthens the brain’s resilience to stress. Exercise helps animals cope with stress by enabling an uptick in a crucial neural protein called galanin, the study suggests. This process influences stress levels, food consumption, cognition, and mood.

Leveraging this finding, researchers were able to genetically tweak even sedentary mice’s levels of galanin, shifts that lowered their anxious response to stress.

The study’s authors explain that this study helps pin down the biological mechanisms driving exercise’s positive effects on stress. While further human experiments are needed to confirm these findings, the researchers have practical advice for people looking to get these benefits: perform regular, aerobic exercise.