Lifeboat Foundation

New model for human evolution suggests Homo sapiens arose from multiple closely related populations.

A new study in Nature challenges prevailing theories, suggesting that Homo sapiens evolved from multiple diverse populations across Africa, with the earliest detectable split occurring 120,000–135,000 years ago, after prolonged periods of genetic intermixing.

In testing the genetic material of current populations in Africa and comparing it against existing fossil evidence of early Homo sapiens populations there, researchers have uncovered a new model of human evolution — overturning previous beliefs that a single African population gave rise to all humans. The new research was published on May 17, in the journal Nature.

Solving a notorious quantum quandary could require abandoning some of science’s most cherished assumptions about the physical world.

The Forever Healthy Foundation is pleased to announce the second edition of the Rejuvenation Startup Summit, following the inaugural Rejuvenation Startup Summit in 2022 with more than 400 participants from over 30 countries. It will take place on 10–11 May 2024 in Berlin. The Rejuvenation Startup Summit is the world’s largest in-person gathering of longevity startups. It brings together startups, members of the longevity venture capital / investor ecosystem, and researchers interested in starting or joining a startup – all with the goal of accelerating the development of the rejuvenation biotech industry.

At Blueprint we’ve explored and evaluated hundreds of anti-aging therapies.

Recently, we had a daring idea: what if my father, son and I completed the world’s first ever multi-generational plasma exchange?

Continue reading “Will My Son’s Blood Make Me Younger?” »

The other day a friend proudly told me she wrote a heartwarming graduation card to her teenage son. “Okay,” she confessed. “I

How long was your card? I asked her.

Not only that, but many also couldn’t even generate a topic on their own. They lacked creativity to dream up their own ideas, much less the critical thinking skills to put themselves in the shoes of their audience, imagining what would land. But they all had 4.0 GPAs or higher and came from private schools in Orange County and LA, reflecting our watered-down educational system.

Continue reading “Will AI Produce Useless Humans?” »

Summary: Neurons in the hippocampus vary in function depending on their exact genetic identity. The study revealed these neurons, once believed to be homogeneous, are quite diverse and encode task-related information differently based on their location. This newfound understanding of neuronal diversity could lead to better comprehension of brain functions, memory capacity, and potentially advance disease treatment strategies.

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Summary: Researchers used artificial intelligence to predict how enzymes interact with various substrates. The team developed an AI model that can accurately predict whether an enzyme can work with a particular molecule.

Their enzyme substrate prediction (ESP) model provides a valuable tool for drug research and biotechnology, with applications ranging from the creation of new drugs to the production of biofuels.

Scientists have figured out a way to retrieve tiny traces of human genetic material called environmental DNA (eDNA) from thin air.

Lifespan by simply slowing the aging of an organ, such as the intestine? CNRS researchers have discovered how to extend the life expectancy of zebrafish by reactivating a gene within intestinal cells. The results were published in the journal Nature Aging on May 4, 2023.

The intestine plays a crucial role in an anti-aging approach as well as general health. Over a century ago, Elie Metchnikov observed that aging ensued from increased inflammation of the intestine and microbial infiltration within blood circulation. The more we age, the less the digestive tract serves as a barrier, allowing the undesirable particles and bacteria that cause the more rapid aging of the organism to pass through.

In a new study, Miguel Godinho Ferreira and his team at the Institute for Research on Cancer and Aging (Ircan) in Nice (CNRS/Inserm/Université Côte d’Azur) have studied the impact on aging of telomere length in the intestinal cells of zebrafish. As with humans, these chromosome extremities shrink faster in the intestine than in other organs during the course of a life, which is why this process plays such an important role in aging.