Lifeboat Foundation

DNA has garnered attention for its potential as a programmable material platform that could spawn entire new and revolutionary nanodevices in computer science, microscopy, biology, and more. Researchers have been working to master the ability to coax DNA molecules to self assemble into the precise shapes and sizes needed in order to fully realize these nanotechnology dreams.

For the last 20 years, scientists have tried to design large DNA crystals with precisely prescribed depth and complex features – a design quest just fulfilled by a team at Harvard’s Wyss Institute for Biologically Inspired Engineering. The team built 32 DNA crystals with precisely-defined depth and an assortment of sophisticated three-dimensional (3D) features, an advance reported in Nature Chemistry.

The team used their “DNA-brick self-assembly” method, which was first unveiled in a 2012 Science publication when they created more than 100 3D complex nanostructures about the size of viruses. The newly-achieved periodic crystal structures are more than 1000 times larger than those discrete DNA brick structures, sizing up closer to a speck of dust, which is actually quite large in the world of DNA nanotechnology.

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(Phys.org) —Scientists at the University of Bristol have developed a process where reagents are added to a growing carbon chain with extraordinary high fidelity and precise orientation, thereby controlling the conformation of the molecule so that it adopts a helical or linear shape. The process can be likened to a molecular assembly line.

Nature has evolved highly sophisticated machinery for organic synthesis. One of the most beautiful examples is its machinery for the synthesis of polyketides, a very important class of molecules due to their broad spectrum of biological activities (for example antibiotic, antitumor, antifungal, antiparasitic).

Continue reading “Chemists create ‘assembly-line’ for organic molecules” »

Nanotechnology promises significant advances in electronics, materials, biotechnology, alternative energy sources, and much more.

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Discovery could lead to new source of stem cells for research and treatment.

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Called a shape-memory polymer (SMP) and developed by a team at Texas A&M University in the US, this biodegradable material can be used to fill in gaps in a damaged face and act as a scaffold to guide the growth of existing bones.

The researchers made their shape-memory polymer by linking molecules of another material — polycaprolactone, or PCL — and whipping it into a foam. According to Jackie Hong at Motherboard, the material is soft and easy to mould when heated to 60°C (140°F), and sets when it’s cooled to body temperature without becoming brittle. It can be used in 3D printing and moulding, which means it can be shaped into extremely precise models and bone scaffolds, and it’s full of tiny holes like a sponge, which allows bone-producing cells called osteoblasts to collect inside and grow.

According to Hong, the researchers enhanced this osteoblast-growing effect by coating their SMP material in polydopamine — a different kind of polymer substance that helps bind existing bones to the SMP scaffold, and has been shown in previous studies to encourage the growth of osteoblasts. Over a three-day trial, their coated SMP scaffold grew five times more osteoblasts than their uncoated scaffold.

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Got a nasty burn? Nanogel has you covered. Using the power of nanotechnology, this cutting-edge simply sprays burns away, and speeds the healing process.

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We believe in harnessing the power of biology to make transformative products that are good for business, people and the environment. By applying the latest in automation, data architecture and machine learning, we’re making better microbes for use in industrial fermentation.

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Researchers at MIT and Boston Children’s Hospital have developed a system that can take MRI scans of a patient’s heart and, in a matter of hours, convert them into a tangible, physical model that surgeons can use to plan surgery.

The models could provide a more intuitive way for surgeons to assess and prepare for the anatomical idiosyncrasies of individual patients. “Our collaborators are convinced that this will make a difference,” says Polina Golland, a professor of electrical engineering and computer science at MIT, who led the project. “The phrase I heard is that ‘surgeons see with their hands,’ that the perception is in the touch.”

This fall, seven cardiac surgeons at Boston Children’s Hospital will participate in a study intended to evaluate the models’ usefulness.

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In what may seem like a Hollywood blockbuster, Defense Advanced Research Projects Agency (DARPA) has developed an implant that goes directly onto the human brain.

The agency wrote in a statement their device is showing promise with improving patient’s memory tests scores. It is “raising hope that such approaches may someday help individuals suffering from memory deficits as a result of traumatic brain injury or other pathologies.”

DARPA’s Restoring Active Memory (RAM) program presented their preliminary findings at the ‘Wait, What? A Future Technology Forum,’ which is also hosted by the agency at St. Louis.

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