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Interview with Dr. Jose Luis Cordeiro at the International Longevity and Cryopreservation Summit in Madrid.


During the recent International Longevity and Cryopreservation Summit in Madrid, LEAF Board member Elena Milova had the opportunity to speak with Dr. Jose Luis Cordeiro new fellow of the World Academy of Art and Science (WAAS) and long-term proponent of innovation technologies in many fields. Jose shared his vision on how public perception of rejuvenation technologies is changing over time and what are the main outcomes of the groundbreaking show he and his team managed to organize.

Dr. Cordeiro got his B.Sc. and M.Sc. degrees in Mechanical Engineering at the Massachusetts Institute of Technology (MIT) in Cambridge, USA, with a minor in Economics and Languages. He is President Emeritus of the Future World Society (Venezuela) and since its foundation about two decades ago Jose managed to become an influential futurist. He is a founding faculty at NASA created Singularity University in Silicon Valley. The goal of the research centre is to tackle global problems such as health, nutrition, poverty and education using the medium of technology. He is also on the board of directors for the Lifeboat Foundation. Jose is part of Fundacion VidaPlus, promoting rejuvenation technologies as well as cryonics, as he believes that people who are too old to make use of the emerging biotechnologies should be granted a plan B in form of cryopreservation. Apart from traveling all over the world to promote innovative ideas in his inspiring talks, Jose has written more than 10 books and co-written over 20 more in five languages, including sections of the State of the Future by the Millennium Project. His extensive associations and achievements are far too numerous to list in this short article, and we invite you to read more about Jose here and also watch his awesome TEDx talk here.

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B rain surgery is one of the most delicate, invasive procedures in medicine. Many times, anesthesia is not involved; sometimes, an electrode is inserted into the brain for deep brain stimulation.

Research published Thursday in the journal Cell promises a safer alternative to these otherwise intrusive ways to get in your head: stimulating neurons deep in the brain without any invasive procedures. The procedure, called temporal interference stimulation, is the latest invention of MIT neuroscientist and engineer Edward Boyden.

“Brief stimulation of the brain can actually cause the brain to clean up the amyloid plaques that are a hallmark of Alzheimer’s Disease,” Boyden tells Inverse. He feels that his new technology can help with a number of neurological conditions without many of the hazards inherent to invasive techniques.

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Could AI soon diagnose cancer? New system that ‘doctors can rely on’ is 93% accurate in identifying tumours.

  • US firm IBM says its Watson system is capable of accurately identify tumours
  • The computer crunches through medical images and patient records quickly
  • It compares them to past cases and medical journals to come to a conclusion
  • Doctors at 55 hospitals around the world have been using the AI to help them

By Richard Gray for MailOnline

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Increasing autophagy in macrophages is a promising avenue of research aiming at heart disease and other age-related diseaeses.


Today we thought it was a good time to take a look at a new study that demonstrates that increasing autophagy is a good approach to slowing aging and could be the foundation for a variety of therapies to treat age-related diseases.

What is Autophagy?

Autophagy is an intracellular degradation system that delivers unwanted cell components to a type of cellular garbage disposal system, known as the lysosome. The lysosome uses powerful enzymes that break down the unwanted material for recycling. However, as we age the lysosomes become clogged up with materials that are so fused together not even the potent enzymes can destroy them and this causes the lysosomes to become dysfunctional and eventually the cell dies. This is a particular problem for long lived cells with a very low rate of replacement such as the heart, the back of the eye, nerve cells and other cells that rarely divide if at all. Ultimately as more and more cells become dysfunctional over time due to lysosome dysfunction, tissue function become impaired and age-related disease sets in.

Ah, my sweet summer child. What do you know of inflammation? Inflammation is for the winter, when genes uncoil in your blood and messengers send codes containing the blueprints for proteins to protect you from the harsh diseases of the cold. Inflammation is for those long nights, when the sun hides its face, or rain clouds block the sky, and trillions of little T-cells are born to fight the diseases of cold and flu season.

At least, that’s the news from a new study showing that DNA reacts to the seasons, changing your body’s chemistry depending on the time of year.

The findings, published today in Nature Communications ^1^, show that as many as one-fifth of all genes in blood cells undergo seasonal changes in expression. Genes often are seen as immutable, but a lot of our body’s workings depend upon which genes are translated when. In the winter, the study found, your blood contains a denser blend of immune responders, while summer veins swim with fat-burning, body-building, water-retaining hormones. These seasonal changes could provide insight into inflammatory diseases like hypertension, and autoimmune diseases like type 1 diabetes.

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The age of the cyborg may be closer than we think. Rapidly improving medical robotics, wearables, and implants means many humans are already part machine, and this trend is only likely to continue.

It is most noticeable in the field of medical prosthetics where high-performance titanium and carbon fiber replacements for limbs have become commonplace. The use of “blades” by Paralympians has even raised questions over whether they actually offer an advantage over biological limbs.

For decades, myoelectric prosthetics—powered artificial limbs that read electrical signals from the muscles to allow the user to control the device—have provided patients with mechanical replacements for lost hands.

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From portable genome sequencers until genetic tests revealing distant relations with Thomas Jefferson, genomics represents a fascinatingly innovative area of healthcare. As the price of genome sequencing has been in free fall for years, the start-up scene is bursting from transformative power. Let’s look at some of the most amazing ventures in genomics!

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