Lifeboat Foundation

When the Shewanella oneidensis bacterium “breathes” in certain metal and sulfur compounds anaerobically, the way an aerobic organism would process oxygen, it produces materials that could be used to enhance electronics, electrochemical energy storage, and drug-delivery devices.

The ability of this bacterium to produce molybdenum disulfide—a material that is able to transfer electrons easily, like graphene—is the focus of research published in Biointerphases by a team of engineers from Rensselaer Polytechnic Institute.

“This has some serious potential if we can understand this process and control aspects of how the bacteria are making these and other materials,” said Shayla Sawyer, an associate professor of electrical, computer, and systems engineering at Rensselaer.

Through a cross-species study of metformin, a common drug used to treat Type 2 diabetes, a team of researchers and clinicians from the Donnelly Center and The Hospital for Sick Children (SickKids) has shown that it could one day be possible to repair brain injury using resident cells in the brain.

“No one’s actually shown before that you can take a drug where there’s a known mechanism on endogenous stem cells and demonstrate that it’s even possible to induce brain growth and positive recovery,” says Donald Mabbott, Program Head and Senior Scientist in the Neurosciences & Mental Health program at SickKids, and co-author of a study published in Nature Medicine on July 27.

Mabbott says metformin is a potential game-changer in terms of how childhood brain injury is treated.

This sucks.

Per- and polyfluoroalkyl substances (PFAS), found in many household products and food packages, have raised concerns because of their persistence and possible toxicity to people and wildlife. Because the compounds don’t break down naturally, they have become environmental contaminants. Now, researchers reporting in Environmental Science & Technology have studied the transport of 29 PFAS into and out of the Arctic Ocean, detecting a newer compound for the first time in Arctic seawater.

After studies indicated that two PFAS—PFOA and PFOS—can cause cancer, a compromised immune response and other health problems in lab animals, the two compounds were voluntarily phased out by industry. However, these legacy compounds are still widely detected in the environment. Intended as a safer replacement for PFOA, HFPO-DA (sold under the trade name GenX) is now thought to pose similar health and persistence concerns. Hanna Joerss and colleagues wanted to investigate the long-range, oceanic transport of legacy and replacement PFAS to the Arctic Ocean—a remote body of water connected to the Atlantic Ocean by the Fram Strait, which is located between Svalbard and Greenland.

Continue reading “Newer PFAS compound detected for first time in Arctic seawater” »

Summary: First responders at the World Trade Center have reduced cortical gray matter thickness, which was consistent with neurodegenerative conditions and evidence their brain age is, on average, ten years older than those of similar ages in the general population.

Source: Stony Brook University

Two studies led by Stony Brook University researchers to be presented virtually at the Alzheimer’s Association International Conference on July 28, 2020, indicate that World Trade Center (WTC) first responders are at risk for developing dementia. The studies included individuals with signs of cognitive impairment (CI) who show neuroradiological abnormalities and changes in their blood similar to that seen in Alzheimer’s disease patients and those with related dementias.

AMID rising global numbers of daily coronavirus infections, a fresh flush of vaccine trial results is offering hope for the longer run.

There are more than 160 coronavirus vaccines in development around the world. About 140 of these are at the preclinical stage, meaning they are still being looked at in laboratories and in animal tests. Another 25 are already being tested in people.

Okay now this vaccine thing is just comedy:

Russia intends to be the first in the world to approve a coronavirus vaccine, in less than two weeks — despite concerns about its safety, effectiveness and over whether the country has cut essential corners in development, CNN has learned.

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Continue reading “Russia aims to approve Covid-19 vaccine” »

TORONTO — In a lab at the Hospital for Sick Children in Toronto, scientists went on a hunt through the DNA of some 10,000 families — many whom have children with autism.

Through this research, they identified something they call “genetic wrinkles” in DNA itself, a breakthrough they believe could explain why some individuals find themselves on the autistic spectrum.

The hope is that this could be an important new clue into how to diagnose autism spectrum disorder (ASD) early, or even treat it.

An Artificial Intelligence tool to help funders identify specialists to peer-review proposals for emergency research has been developed by Frontiers. It aims to help fast-track the allocation of funding, and in turn, accelerate the scientific response.

An Artificial Intelligence (AI) tool to help funders identify specialists to peer-review proposals for emergency COVID-19 research has been developed. It aims to help fast-track the allocation of funding, and in turn, accelerate the scientific response to the virus.

The open-access publisher Frontiers has specifically developed the recommendation tool to aid funders during the crisis by helping them identify new reviewers. Under normal circumstances, the review process for research funding typically takes place by committee and can take a matter of months. However, since the COVID-19 outbreak, experts have become less available, and the urgency of this situation commands a tighter timeframe.

Continue reading “Artificial intelligence to enable fast-track review of COVID-19 research proposals” »

Developed by a Sino-US startup, the groundbreaking new blood test is referred to as PanSeer.