New program aims to build and demonstrate ruggedized device for tactical applications.
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DARPA Looks to Light up Integrated Photonics with Chip-Scale Laser DevelopmentAgency announces performer teams selected for LUMOS program.
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Japan’s Prime Minister Yoshihide Suga has declared a state of emergency for the nation’s capital and surrounding areas as Covid-19 cases surge to the highest levels since the start of the pandemic.
The emergency declaration will be in place from Friday until February 7 and applies to Tokyo and the three neighboring prefectures of Chiba, Saitama and Kanagawa. The emergency includes a number of restrictions on daily life.
Suga has ordered companies to encourage their staff to work from home and reduce office populations by 70%.
Aging is, at least for now, inevitable, and our eyes are not immune to those changes. Vision loss is, in fact, one of the top 10 causes of disability in the US., however, shows that this might be reversible in the future.
A large team of geneticists, ophthalmologists, and other scientists used a group of molecules called Yamanaka factors to turn cells in the eyes of mature mice back to a youthful state. This reversed the damage done by aging, and the cells were then able to regenerate, connect back to the brain, and vision was restored in both models of normal aging and glaucoma.
Continue reading “Scientists have restored youth to aging eyes in mice” »
O,.o wut? Circa 2016.
Let’s talk about negligible senescence, and how crocodiles technically never age. In the end it’s injury or disease that gets them.
Watch out, George Lucas, there’s a new attack of the clones, and these ones are furry.
Japanese researchers have created a potentially endless line of mice cloned from other cloned mice. They used the same technique that created Dolly the sheep to produce 581 mice from an original donor mouse through 25 rounds of cloning, the scientists report in the March 7 issue of the journal Cell Stem Cell.
“This technique could be very useful for the large-scale production of superior-quality animals, for farming or conservation purposes,” study leader Teruhiko Wakayama of the RIKEN Center for Developmental Biology in Kobe, Japan, said in a statement.
O,.o circa 2020.
Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders.
A study, published today in the journal Cell Reports, describes how the new UCLA-developed device, called MitoPunch, transfers mitochondria into 100000 or more recipient cells simultaneously, which is a significant improvement from existing mitochondrial transfer technologies. The device is part of the continued effort by UCLA scientists to understand mutations in mitochondrial DNA by developing controlled, manipulative approaches that improve the function of human cells or model human mitochondrial diseases better.
CRISPR gene editing in mice has been used to correct a mutation that can cause rapid ageing, dramatically improving the animals’ health and lifespan.
New gene-editing technology could be used to save species from extinction—or to eliminate them.
In Michelle O’Malley’s lab, a simple approach suggests a big leap forward in addressing the challenge of antibiotic-resistant bacteria.
Scientists have long been aware of the dangerous overuse of antibiotics and the increasing number of antibiotic-resistant microbes that have resulted. While over-prescription of antibiotics for medicinal use has unsettling implications for human health, so too does the increasing presence of antibiotics in the natural environment. The latter may stem from the improper disposal of medicines, but also from the biotechnology field, which has depended on antibiotics as a selection device in the lab.
“In biotech, we have for a long time relied on antibiotic and chemical selections to kill cells that we don’t want to grow,” said UC Santa Barbara chemical engineer Michelle O’Malley. “If we have a genetically engineered cell and want to get only that cell to grow among a population of cells, we give it an antibiotic resistance gene. The introduction of an antibiotic will kill all the cells that are not genetically engineered and allow only the ones we want — the genetically modified organisms [GMOs] — to survive. However, many organisms have evolved the means to get around our antibiotics, and they are a growing problem in both the biotech world and in the natural environment. The issue of antibiotic resistance is a grand challenge of our time, one that is only growing in its importance.”
