Lifeboat Foundation

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don’t fold the way they’re supposed to, it can lead to the development of diseases such as cancer.

Researchers at the Sloan Kettering Institute have uncovered important findings about what causes chaperones to malfunction as well as a way to fix them when they go awry. The discovery points the way to a new approach for developing targeted drugs for cancer and other diseases, including Alzheimer’s disease.

“Our earlier work showed that defects in chaperones could lead to widespread changes in cells, but no one knew exactly how it happened,” says SKI scientist Gabriela Chiosis, senior author of a study published June 30 in Cell Reports. “This paper finally gets into the nuts and bolts of that biochemical mechanism. I think it’s a pretty big leap forward.”

Coronavirus was first detected in China. Over 10 million people have so far infected with the virus across the world while more than five lakh people have died of the disease.

Over 100 research institutions around the world are trying to develop a vaccine to deal with the virus. It was reported that the Oxford vaccine is now at the final stage.

But above all, China has now given final approval to the corona vaccine, according to a report of Yahoo News.

Two documents dating back to 2015 shed further light on the role the federal government played in discovering remdesivir and its use in treating coronaviruses — work that has taken on new meaning as the Gilead Sciences (GILD) drug has gained global attention and an emergency use authorization from federal regulators to treat patients with Covid-19.

Reporting from the frontiers of health and medicine.

The maker of a drug shown to shorten recovery time for severely ill COVID-19 patients says it will charge $2,340 for a typical treatment course for people covered by government health programs in the United States and other developed countries.

Gilead Sciences announced the price Monday for remdesivir, and said the price would be $3,120 for patients with private insurance. The amount that patients pay out of pocket depends on insurance, income and other factors.

“We’re in uncharted territory with pricing a new medicine, a novel medicine, in a pandemic,” Gilead’s chief executive, Dan O’Day, told The Associated Press.

He uses a code word for racist, because he is alt right.

Elon Musk said we need “some kind of mind viral immunity” to protect against the interconnected meme sphere.

Continue reading “Elon Musk says he sympathizes with ‘anti-globalization people’ because the online world is too interconnected and could lead to a ‘mind virus’” »

Research at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has led to the revolutionary development of an artificial liquid retinal prosthesis to counteract the effects of diseases such as retinitis pigmentosa and age-related macular degeneration that cause the progressive degeneration of photoreceptors of the retina, resulting in blindness. The study has been published in Nature Nanotechnology.

The study represents the state of the art in retinal prosthetics and is an evolution of the planar artificial retinal model developed by the same team in 2017 and based on organic semiconductor materials (Nature Materials 2017, 16: 681–689).

The ‘second generation’ artificial retina is biomimetic, offers high spatial resolution and consists of an aqueous component in which photoactive polymeric nanoparticles (whose size is 350 nanometres, thus about 1/100 of the diameter of a hair) are suspended, and will replace damaged photoreceptors.

https://youtube.com/watch?v=p949fSZVVLM

The spiral pattern shown by the galaxy in this image from the NASA /ESA Hubble Space Telescope is striking because of its delicate, feathery nature. These “flocculent” spiral arms indicate that the recent history of star formation of the galaxy, known as NGC 2775, has been relatively quiet. There is virtually no star formation in the central part of the galaxy, which is dominated by an unusually large and relatively empty galactic bulge, where all the gas was converted into stars long ago.

NGC 2275 is classified as a flocculent spiral galaxy, located 67 million light-years away in the constellation of Cancer.

Continue reading “Birds of a Feather: Hubble Images Magnificent Galaxy With ‘Flocculent’ Spiral Arms” »

Disinfecting spaces such as warehouses is especially critical during the COVID-19 pandemic, but doing so while keeping workers safe can be challenging. So MIT’s Computer Science and Artificial Intelligence Laboratory came up with a solution: use a robot that employs UV-C light to disinfect surfaces and neutralize aerosolized forms of coronavirus.

Through a collaboration with Ava Robotics and the Greater Boston Food Bank, CSAIL mounted a custom UV-C lamp on an Ava Robotics mobile robot base. The lamp neutralizes around 90% of surface microorganisms, according to CSAIL. The robot is initially operated by a remote user and subsequently works autonomously, and can disinfect 4,000 square feet of warehouse space in half an hour.

The new strain, scientists say, is carried by pigs but can infect humans and requires close monitoring.