Lifeboat Foundation

T cells that attack apolipoprotein B, the main component of “bad” cholesterol, could be contributing to inflammation that worsens heart disease.

Cell-Based Dairy Bio-Products For Health & Nutrition — Dr. Aletta Schnitzler, Ph.D. — CSO — Turtletree Labs

Dr. Aletta Schnitzler, PhD. is the Chief Scientific Officer at TurtleTree Labs (https://turtletree.com/) where she leads the R&D teams and spearheads an innovation roadmap to bring nutritious cell-based dairy and meat alternatives to market.

Continue reading “Dr Aletta Schnitzler — CSO — TurtleTree Labs — Cell-Based Dairy Bio-Products For Health & Nutrition” »

Summary: Study reveals the ZNF117 gene is a major regulator of glioblastoma tumor cells.

Source: Yale.

A recent research paper published in Nature Communications by a team led by Yale School of Medicine researchers finds a promising way to make brain cancer cells more susceptible to chemotherapy.

A mechanism that causes autism, schizophrenia, Alzheimer’s and other conditions and is shared by mutations in the genes ADNP and SHANK3 has been unraveled by Tel Aviv University researchers who developed an experimental drug they found to be effective in animal models.

The drug could also be suitable for treating a range of rare syndromes that impair brain functions, said the scientists. The researchers were led by Prof. Illana Gozes from the Department of Human Molecular Genetics and Biochemistry at TAU’s Sackler Faculty of Medicine and the Sagol School of Neuroscience. The experimental drug, called Davunetide, had previously been developed in her lab.

The paper, which the team called a “scientific breakthrough,” was published in the scientific journal Molecular Psychiatry under the title “SH3-and actin-binding domains connect ADNP and SHANK3, revealing a fundamental shared mechanism underlying autism.”

A total lunar eclipse is an incredible sight. As Earth passes between the Moon and the Sun, its shadow slips across the face of our satellite so only long, red wavelengths – sunlight refracted by Earth’s atmosphere – can slip through, tinting the usually pale Moon blood-red.

That’s when we see it from here, on our planet. But from space, the view is very different – and now we can see what that looks like, thanks to the asteroid probe Lucy, led by the Southwest Research Institute (SwRI), launched in October 2021.

Continue reading “A Spacecraft Just Recorded The Lunar Eclipse Like You’ve Never Witnessed It Before” »

Researchers have created autonomous particles covered with patches of protein “motors.” They hope these bots will tote lifesaving drugs through bodily fluids.

The field of female reproductive longevity and inequality is getting more and more attention. In fact, it is one of the hottest areas of the emerging longevity biotechnology industry, and every venture firm in the field is either investing, incubating, or looking for projects in this area. Companies like BOLD Capital, Future Ventures, LongeVC, and iconic biotechnology investors including Bob Nelsen and Christian Angermayer, are all active and significant partners in this area of science. While females generally live longer than men, their reproductive period is limited—something that is often overlooked. A female’s peak reproductive years are between the late teens and late 20s. Fertility starts to decline by age 30, and this decline becomes more rapid once women reach the mid-30s. By 45, fertility declines so much that getting pregnant naturally is unlikely for most women. Likewise, women begin life with a fixed number of eggs in their ovaries, usually around one million. This number decreases as women age. Ovaries age faster than the rest of a woman’s body—an understudied phenomenon of a neglected organ. None of us would be here without them. Yet surprisingly little is known about the avocado-shaped organ that’s nestled inside half of all humans.

The ovaries also influence a woman’s overall health and well-being. This includes how they age, since this organ tends to lose its function with age faster than any other tissue. This is called asynchronous aging, and it’s one reason why a woman’s fertility declines, and menopause strikes, while they are still relatively young.

In one of my previous articles, I wrote about Gameto, a biotechnology company that is translating the impact of ovarian aging to develop solutions to improve fertility and stop the impact of menopause on female health. Gameto’s co-founder and CEO Dina Radenkovic told me about her intention to redefine the narrative around female reproductive longevity and making it more around health and longevity. Gameto is building a platform for ovarian therapeutics to address menopause and improve assisted fertility. Dina told me she hopes it will make women suffer fewer health problems in their later lives. Neglecting the ovaries—except for their crucial role in IVF treatments—has been part of a general disregard for many aspects of women’s health in the biomedical world.

Researchers at Stanford University are reversing symptoms of Alzheimer’s in mice using a strange tactic — they’re infusing elderly mice with spinal fluid from younger ones.

Many medical breakthroughs that benefit humans are discovered by conducting trials on mice.

Though we look nothing alike, almost all the genes found in mice have similar functions to genes in humans. We get diseases for the same reasons, meaning scientists can study illnesses closely in mice to understand how they manifest in us.

Continue reading “Scientific breakthrough cures memory loss in mice” »