Lifeboat Foundation

At the mere flick of a magnetic field, mice engineered with nanoparticle-activated ‘switches’ inside their brains were driven to feed, socialize, and act like clucky new mothers in an experiment designed to test an innovative research tool.

While ’mind control’ animal experiments are far from new, they have generally relied on cumbersome electrodes tethering the subject to an external system, which not only requires invasive surgery but also sets limits on how freely the test subject can move about.

In what is claimed to be a breakthrough in neurology, researchers from the Institute for Basic Science (IBS) in Korea have developed a method for targeting pathways in the brain using a combination of genetics, nanoparticles, and magnetic fields.

A new smart monitoring system could help doctors avoid mistakes—but it’s also alarming some surgeons and leading to sabotage.

Ending Alzheimer’s Disease Everywhere — Dr. Tim MacLeod, PhD & Dr. Vaibhav Narayan, PhD, Davos Alzheimer’s Collaborative.

Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a “one-size-fits-all” remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a high number of senescent cells, according to findings publishing July 2 in Nature Medicine.

Senescent cells are malfunctioning cells in the body that lapse into a state of dormancy. These cells, also known as “zombie cells,” can’t divide but can drive chronic inflammation and tissue dysfunction linked to aging and chronic diseases. Senolytic drugs clear tissues of senescent cells.

In the 20-week, phase 2 randomized controlled trial, 60 healthy women past menopause intermittently received a senolytic combination composed of FDA-approved dasatinib and quercetin, a natural product found in some foods. It is the first randomized controlled trial of intermittent senolytic treatment in healthy aging women, and the investigators used bone metabolism as a marker for efficacy.

In a public interview, Chinese biophysicist He Jiankui said he is receiving offers of financial support from figures in the US.

🧠🤖🩺

Research develops an automated system using machine learning to quantify motor symptoms in Parkinson’s disease and predict disease progression, offering new therapeutic insights.

An algorithm developed by Washington State University researchers can better find data anomalies than current anomaly-detection software, including in streaming data.

The work, reported in the Journal of Artificial Intelligence Research, makes fundamental contributions to artificial intelligence (AI) methods that could have applications in many domains that need to quickly find anomalies in large amounts of data, such as in cybersecurity, power grid management, misinformation, and medical diagnostics.

Being able to better find the anomalies would mean being able to more easily discover fraud, disease in a medical setting, or important unusual information, such as an asteroid whose signals overlap with the light from other stars.

A new study shows that suppressing a protein turns ordinary fat into a calorie burner and may explain why drug trials attempting the feat haven’t been successful.

Researchers at UC San Francisco have figured out how to turn ordinary white fat cells, which store calories, into beige fat cells that burn calories to maintain body temperature.

The discovery could open the door to developing a new class of weight-loss drugs and may explain why clinical trials of related therapies have not been successful.

An international team of scientists, including two researchers who now work in the Center for Advanced Sensor Technology (CAST) at UMBC, has shown that twisted carbon nanotubes can store three times more energy per unit mass than advanced lithium-ion batteries. The finding may advance carbon nanotubes as a promising solution for storing energy in devices that need to be lightweight, compact, and safe, such as medical implants and sensors. The research was published recently in the journal Nature Nanotechnology.