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Jul 26, 2024

Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes

Posted by in categories: biotech/medical, health, nanotechnology, neuroscience

In a recent study published in Neuron, researchers discovered that microglia, the brain’s immune cells, use tunneling nanotubes…


Scheiblich et al. uncover a novel mechanism by which microglia use tunneling nanotubes to connect with α-syn-or tau-burdened neurons, enabling transfer of these proteins to microglia for clearance. Microglia donate mitochondria to restore neuronal health, shedding light on new therapeutic strategies for neurodegenerative diseases.

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