Lifeboat Foundation

Researchers from Tohoku University and Kyoto University have successfully developed a DNA-based molecular controller that autonomously directs the assembly and disassembly of molecular robots. This pioneering technology marks a significant step towards advanced autonomous molecular systems with potential applications in medicine and nanotechnology.

Details of the breakthrough were published in the journal Science Advances (“Autonomous assembly and disassembly of gliding molecular robots regulated by a DNA-based molecular controller”).

“Our newly developed molecular controller, composed of artificially designed DNA molecules and enzymes, coexists with molecular robots and controls them by outputting specific DNA molecules,” points out Shin-ichiro M. Nomura, an associate professor at Tohoku University’s Graduate School of Engineering and co-author of the study. “This allows the molecular robots to self-assemble and disassemble automatically, without the need for external manipulation.”