“Identification of these compounds means that we are one step closer to being able to molecularly diagnose dementia,” said senior author of the study, Professor Mitsuhiro Yanagida, who leads the G0 Cell Unit at OIST.
Summary: Researchers identified 33 metabolic compounds in blood samples that differed between those with dementia and cognitively healthy older adults. 7 of the metabolites were elevated in dementia patients, while 26 were at lower levels compared to samples of those without dementia. Elevating levels of those metabolites could have a neuroprotective effect against dementia.
Source: OIST
Scientists in Japan have identified metabolic compounds within the blood that are associated with dementia.
The study revealed that the levels of 33 metabolites differed in patients with dementia, compared to elderly people with no existing health conditions. Their findings, published this week in PNAS, could one day aid diagnosis and treatment of dementia.
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