Circa 2020
Regular and frequent blood glucose monitoring is vital in managing diabetes treatment plans and preventing severe complications. Because current invasive techniques impede patient compliance and are not infection-free, many noninvasive methods have been proposed. Among them, optical methods have drawn much attention for their rich optical contrast, but their resolution is degraded in deep tissue. Here, we present an ultrasound-modulated optical sensing (UOS) technique to noninvasively monitor glucose that uses an infrared laser (1645 nm) and a single-element focused ultrasound transducer. Focused ultrasound waves can acoustically localize diffused photons in scattering media, and thus optical contrast can be represented with much enhanced spatial resolution.
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