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Apr 23, 2019

Scientists create first billion-atom biomolecular simulation

Posted by in categories: biotech/medical, genetics

Researchers at Los Alamos National Laboratory have created the largest simulation to date of an entire gene of DNA, a feat that required one billion atoms to model and will help researchers to better understand and develop cures for diseases like cancer.

“It is important to understand DNA at this level of detail because we want to understand precisely how turn on and off,” said Karissa Sanbonmatsu, a structural biologist at Los Alamos. “Knowing how this happens could unlock the secrets to how many diseases occur.”

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Apr 23, 2019

The ‘world’s first malaria vaccine’ is being rolled out in Malawi

Posted by in categories: biotech/medical, health

A malaria vaccine which is being called the first to give partial protection against the disease, is being rolled out in Malawi. It works by training the immune system to attack the malaria parasite which is spread by mosquito bites. In a few weeks it will be rolled out in Kenya and then Ghana. BBC Newsday’s Lawrence Pollard spoke to Dr David Schellenberg who has been working on the development of the vaccine with the World Health Organisation in Geneva.

(Photo: Malawians going through a medical checkup by a paramedic Credit: MAURICIO FERRETTI/AFP/Getty Images)

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Apr 23, 2019

Light-based computer hardware that can compete with silicon

Posted by in categories: business, computing, quantum physics

A team of researchers at NTT Corporation has developed a way to use light-based computer hardware that allows it to to compete with silicon. In their paper published in the journal Nature Photonics, the group describes their research, the devices they created and how well they worked.

Computer scientists have known for some time that the era of increasing speed by modifying silicon-based computer parts is coming to an end. To that end, many have turned to quantum computing as the way to speed up computers—but to date, such efforts have not led to useful machines and there is no guarantee they ever will. Because of that, others in the are looking for other options, such as using to move data around inside of computers instead of electrons. Currently, light is generally only used to carry data long distances. In this new effort, the researchers report that they have developed computing devices based partially on light that performed as well as electron-based hardware.

The idea of using only light as a data medium in is still a long way off—instead, engineers are focusing on using light in areas where it seems feasible and electrons everywhere else. Because of that computer devices must be able to convert between the two mediums, a problem that until now has prevented such devices from being built. Prior efforts have required too much power to be feasible and the conversion process has been too slow. To get around both problems, the researchers developed a new kind of photonic crystal that was able to diffuse light in a way that allowed it to follow a designated path on demand and to also be absorbed when needed to be used for generating current. The crystal was also able to work in reverse.

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Apr 23, 2019

Synthetic molecule shows promise as multiple sclerosis treatment

Posted by in categories: biotech/medical, neuroscience

In multiple sclerosis, the body’s immune system attacks and damages myelin, which is the insulating layer on nerves in the spinal cord, brain and optic nerve. This causes the nerves to short-circuit and cease functioning properly. In “a potential game-changer,” scientists have now demonstrated that a synthetic molecule can restore compromised myelin.

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Apr 23, 2019

Falsifiability and physics

Posted by in category: physics

Can a theory that isn’t completely testable still be useful to physics?

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Apr 23, 2019

A ‘Blockchain Bandit’ Is Guessing Private Keys and Scoring Millions

Posted by in categories: bitcoin, cryptocurrencies

The larger lesson of an ongoing Ethereum crime spree: Be careful with who’s generating your cryptocurrency keys.

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Apr 23, 2019

Feeble humans prove no match for OpenAI’s Dota 2 gods

Posted by in category: robotics/AI

The AI won 7,215 matches against humans, losing only 42 in the process.

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Apr 23, 2019

Elon Musk says Neuralink joining humans with computers ‘coming soon’

Posted by in categories: Elon Musk, robotics/AI

Elon Musk believes humans must link up with machines in order to fight the inevitable onslaught of artificial intelligence.

In a recent tweet, the SpaceX and Tesla CEO said technology from his latest company, Neuralink, will be ‘coming soon.’

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Apr 23, 2019

Eye implant improves vision in people with age-related blindness

Posted by in category: life extension

A patch of cells implanted at the back of the eye has stabilised and in some cases improved the vision of four people with dry age-related macular degeneration.

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Apr 23, 2019

Old Cells Reprogrammed into MSCs Are Rejuvenated

Posted by in categories: biotech/medical, life extension

Mesenchymal stem cells (MSCs) have been a topic of great interest in the last decade or so due to their ability to improve tissue regeneration merely by their presence and the secreted signals they give out.

Adult MSCs have traditionally been used for regenerative medicine with hit-and-miss results, depending on the quality and age of the harvested MSCs. It has been discovered in recent years that the efficacy of these cells greatly depends on how damaged by aging they are, which explains why MSC therapy sometimes works very well in one person but not so much in another.

However, what about aged cells that are reprogrammed back to pluripotency then guided into becoming mesenchymal stem cells through cellular reprogramming?

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