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Feb 8, 2019
Nested CRISPR enables efficient genome editing using long DNA fragments
Posted by Paul Battista in categories: biotech/medical, genetics
CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a single or few nucleotides with relative ease, it still possesses limitations for larger fragments of DNA in the genome. For instance, the genomic insertion of a gene that produces a fluorescent protein such as the widely-used GFP suffers from poor efficiency and involves complicated cloning steps.
Feb 8, 2019
Robo-Dogs May Soon Deliver Your Packages
Posted by Shailesh Prasad in category: robotics/AI
Feb 8, 2019
This Star Trek–like replicator can create entire objects in minutes
Posted by Paul Battista in category: futurism
Feb 8, 2019
Are Intellectuals Suffering a Crisis of Meaning?
Posted by Xavier Rosseel in category: neuroscience
Ignorance is bliss, until it isn’t…,and it becomes experience.
“We fail our most cognitively talented students when we set them up for adult expectations that they must be high achieving, or we don’t help them find their own unique path to self-actualization and contribution to society. In today’s polarized world, with a general lack of nuance and open and honest critical discussions, I also think a very large number of intellectually gifted children are growing up knowing they are bright, but wondering: what for?”
What is the relationship between intellectual giftedness and meaning in life?
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Feb 8, 2019
A New Cocktail of Proteins Makes Mice Regenerate Toes Like Lizards
Posted by Albert Sanchez in category: futurism
Feb 8, 2019
Volunteer to Help Build Artificial General Intelligence based on Human-like Emotions
Posted by Mark Larkento in category: robotics/AI
~ David J. Kelley
Essentially, we are asking for volunteers to be part of one or two of three groups that will help us conduct a cognitive function high-level study of a type of Artificial General Intelligence (AGI) based on a cognitive architecture termed the Independent Core Observer Model (ICOM). Yes, I realize this is a lot of complex technospeak, but if you want to really get technical you can refer to a glossary and references (at the end of this document)—but primarily, I’ll try to keep the details in a more non-AI scientist sort of language (meaning normal English).
That said, what you are volunteering for is, again, to be part of one or two out of three research groups that will perform a type of task depending on your ability to participate—and you get to select the group that works best for you. From our statistical standpoint, our resident research psychologist Dr. Amon Twyman) has stated that we need these groups to be a certain size to ensure that we can obtain even vague conclusions—so we need more help to ensure our pool size is large enough.
Feb 8, 2019
What.IfVideosWhat If Earth Orbited Betelgeuse
Posted by Michael Lance in category: space
Betelgeuse is 900 times larger than our sun and astronomers think it’s about to explode. What if Earth orbited this giant monster of a star?
Feb 8, 2019
Chronic rhinosinusitis linked to depression, anxiety
Posted by Xavier Rosseel in categories: biotech/medical, neuroscience
(HealthDay)—Chronic rhinosinusitis (CRS) is associated with incidence of depression and anxiety, according to a study published online Feb. 7 in JAMA Otolaryngology-Head & Neck Surgery.
Jong-Yeup Kim, M.D., Ph.D., from Konyang University Hospital in Daejeon, South Korea, and colleagues conducted a retrospective nationwide cohort study using population-based insurance data for 16,224 patients with CRS and 32,448 individuals without CRS, with propensity score matching between the groups. The incidence, survival rate, and hazard ratios of depression and anxiety were calculated for each group.
The researchers found that during the 11-year follow-up, the overall incidence of depression was higher in the CRS versus the non-CRS group (24.2 versus 16.0 per 1,000 person-years; adjusted hazard ratio, 1.54). Higher incidence of anxiety was also seen in the CRS versus the non-CRS group (42.2 versus 27.8 per 1,000 person-years; adjusted hazard ratio, 1.57). Compared with patients with CRS with nasal polyps, patients with CRS without nasal polyps had higher adjusted hazard ratios for developing depression (1.61 versus 1.41) and anxiety (1.63 versus 1.45).
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Feb 8, 2019
Navy-Funded Scientist Wins Award for Groundbreaking Seafloor Map
Posted by Genevieve Klien in category: military
Dr. David Sandwell, a geophysicist at Scripps, has been awarded American Geophysical Union’s Charles A. Whitten Medal for creating the world’s first comprehensive, high-resolution map of the ocean floor.
In a long-running project sponsored by the U.S. Navy’s Office of Naval Research, Sandwell combined satellite data with sonar measurements to develop a global depth chart of unprecedented detail. His work has charted thousands of previously unidentified mountains, trenches, and other features in the deepest and least explored parts of the ocean. The work is not only of academic interest: it provides crucial intelligence and scientific information for the Navy.
“Dr. Sandwell’s groundbreaking work provides the first high-resolution map of the ocean floor,” said Dr. Tom Drake, head of ONR’s Ocean Battlespace and Expeditionary Access Department. “This has opened new research areas for oceanography, marine geology and geophysics — critical topics for the U.S. Navy.”
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