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Physicists call the dark energy that drives the universe “the cosmological constant.” Now the largest map of the cosmos to date hints that this mysterious energy has been changing over billions of years.

Explore 10 unique applications of the convolutional neural network that highlights its revolutionary impact on technology.

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

The therapy uses chimeric antigen receptor (CAR) T cells engineered to target the HER2 protein, which is overexpressed on the surface of sarcoma cells. Sarcoma is a type of solid cancer that develops in the bones and soft tissues. The HEROS 2.0 trial showed that this therapeutic approach is safe and is associated with clinical benefit.

“CAR T cell therapy has been a highly successful strategy for recurrent or high-risk leukemias or lymphomas, but challenges remain in using this therapy for solid tumors,” said first and corresponding author Dr. Meenakshi Hegde, associate professor of pediatrics – hematology and oncology at Baylor and pediatric oncologist at Texas Children’s Cancer Center. “The results of this trial show that we are moving the dial in harnessing the power of CAR T cells as an effective anticancer therapy for sarcomas.”

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Retinitis pigmentosa and macular degeneration lead to photoreceptor death and loss of visual perception. Despite recent progress, restorative technologies for photoreceptor degeneration remain largely unavailable. Here, we describe a novel optogenetic visual prosthesis (FlexLED) based on a combination of a thin-film retinal display and optogenetic activation of retinal ganglion cells (RGCs). The FlexLED implant is a 30 µm thin, flexible, wireless µLED display with 8,192 pixels, each with an emission area of 66 µm2. The display is affixed to the retinal surface, and the electronics package is mounted under the conjunctiva in the form factor of a conventional glaucoma drainage implant. In a rabbit model of photoreceptor degeneration, optical stimulation of the retina using the FlexLED elicits activity in visual cortex. This technology is readily scalable to hundreds of thousands of pixels, providing a route towards an implantable optogenetic visual prosthesis capable of generating vision by stimulating RGCs at near-cellular resolution.

### Competing Interest Statement.

All authors have a financial interest in Science Corporation.

Year 2016 face_with_colon_three

Stem cell breakthrough grows new cornea material that restores some sight to blind rabbits in an experiment.

🚨 TECH NEWS: The automaker will deploy Apptronik’s “Apollo” robot at a Mercedes factory in Hungary. Details:

German automaker Mercedes-Benz is deploying Apptronik’s Apollo robots at a manufacturing plant in Hungary.

Tesla has finally decided to release its Autopilot safety data report after taking a break of more than a year.

For years, Tesla used to release a “Vehicle safety report” that tracked miles between accidents in its vehicles based on the level of Autopilot used or not used and compared it to the industry average.

The automaker used the report to claim that its Autopilot technology resulted in a much safer driving experience and that its vehicles would crash much less often than the average car in the US even without Autopilot.

Nuclear physicists have long been working to reveal how the proton gets its spin. Now, a new method that combines experimental data with state-of-the-art calculations has revealed a more detailed picture of spin contributions from the very glue that holds protons together. It also paves the way toward imaging the proton’s 3D structure.