Lifeboat Foundation

Proteins are involved in every biological process, and use the energy in the body to alter their structure via mechanical movements. They are considered biological ‘nanomachines’ because the smallest structural change in a protein has a significant effect on biological processes. The development of nanomachines that mimic proteins has received much attention to implement movement in the cellular environment. However, there are various mechanisms by which cells attempt to protect themselves from the action of these nanomachines. This limits the realization of any relevant mechanical movement of nanomachines that could be applied for medical purposes.

The research team led by Dr. Youngdo Jeong from the Center for Advanced Biomolecular Recognition at the Korea Institute of Science and Technology (KIST, President Seok-Jin Yoon) has reported the development of a novel biochemical nanomachine that penetrates the cell membrane and kills the cell via the molecular movements of folding and unfolding in specific cellular environments, such as cancer cells, as a result of a collaboration with the teams of Prof. Sang Kyu Kwak from the School of Energy and Chemical Engineering and Prof. Ja-Hyoung Ryu from the Department of Chemistry at the Ulsan National Institute of Science and Technology (UNIST, President Yong Hoon Lee), and Dr. Chaekyu Kim of Fusion Biotechnology, Inc.

The joint research team focused on the hierarchical structure of proteins, in which the axis of the large structure and the mobile units are hierarchically separated. Therefore, only specific parts can move around the axis. Most existing nanomachines have been designed so that the mobile components and axis of the large structure are present on the same layer. Thus, these components undergo simultaneous movement, which complicates the desired control of a specific part.

Year 2022 face_with_colon_three

This work rests on our non-viral tissue nanotransfection (TNT) platform to deliver MyoD (TNTMyoD) to injured tissue in vivo. TNTMyoD was performed on skin and successfully induced expression of myogenic factors. TNTMyoD was then used as a therapy 7 days following volumetric muscle loss (VML) of rat tibialis anterior and rescued muscle function. TNTMyoD is promising as VML intervention.

SpaceX crews worked to configure Ship 24 and Booster 7’s flight termination systems for launch, hardware labeled “flame diverter” was spotted at the shipping and receiving area, and foundation work at the production site continued.

🔗 NSF Store: https://www.nasaspaceflight.com/shop/

Continue reading “SpaceX Readies Starship 24 for Flight | SpaceX Boca Chica” »

Banks can attach SWIFT Codes and bank accounts to a UMU digital currency wallet and transaction SWIFT-like cross-border payments over digital currency rails completely bypassing the correspondent banking system at best-priced wholesale FX rates and with instantaneous real-time settlement.

In an IMF interview with Tobias Adrian, Financial Counsellor at the International Monetary Fund, he states “Cross-border payments can be slow, expensive, and risky. In today’s world of payments, counterparties in different jurisdictions rely on costly trusted relationships to offset the lack of a common settlement asset together with common rules and governance. But imagine if a multilateral platform existed that could improve cross-border payments—at the same time transforming foreign exchange transactions, risk sharing, and more generally, financial contracting.”

According to Darrell Hubbard, the Executive Director of the DCMA, and the chief architect of UMU, “This vision expressed by the IMF is the exact solution the DCMA is delivering to central banks worldwide.”

But that’s not true. There are concrete things regulators can do right now to prevent tech companies from releasing risky systems.

In a new report, the AI Now Institute — a research center studying the social implications of artificial intelligence — offers a roadmap that specifies exactly which steps policymakers can take. It’s refreshingly pragmatic and actionable, thanks to the government experience of authors Amba Kak and Sarah Myers West. Both former advisers to Federal Trade Commission chair Lina Khan, they focus on what regulators can realistically do today.

The big argument is that if we want to curb AI harms, we need to curb the concentration of power in Big Tech.

We flew out to Salt Lake City, Utah, to get an exclusive look at the company behind some of the most advanced implantable neurotechnologies, Blackrock Neurotech. Brain implants are here, and they’re becoming more and more advanced every day. The Utah Array and Neuroport system allows for high-quality data recording and stimulation. It has the most in-subject research hours of any brain-computer interface on the market and has been a part of the most advanced BCIs since 2004, inspiring hope in persons with movement disorders. We also saw their newly announced Neuralace interface debuted in November 2022. Learn what it takes to work at a company at the forefront of brain-computer interface development.

Thanks to Blackrock Neurotech for sponsoring this video. The opinions expressed in this video are that of The BCI Guys and should be taken as such.

Continue reading “Behind the Brain Chip: An Inside Look at Blackrock Neurotech” »

Supersonic flight sounds great in theory, but in practice, it can lead to annoying hypersonic booms—the noise associated with shock waves created when an object travels through the air faster than the speed of sound. The booms can be as loud as an explosion or a thunderclap.

Current FAA rules ban supersonic flight over land due to noise pollution. NASA will use the experimental X-59 to gather data in the hopes of reducing the sonic boom to a barely-audible sonic thump heard on the ground. The supersonic plane will fly over populated regions of the United States, and data will be gathered from residents about the sound the aircraft produces.

If the X-59 succeeds in its mission, commercial air travel could get a lot quicker. Dinner in Paris, anyone?

Sorry I’m not that active. My mom had a heart attack a little over a month ago and I care for her now. Plus last Thursday I went to the ER for overdosing accidentally on depakote which can be deadly. But check this out. In case of an emergency is this cool or what? Kind of expensive though.

If this summer you’re in the mood for some off-the-grid camping trips, this state-of-the-art self-sustainable luxury trailer is what you need. Designed from the ground up for off-grid camping, the trailer can also produce its own water, making it fully self-sufficient. This extremely sophisticated camper is the work of a California-based company called Living Vehicle which specializes in making self-sustainable luxury travel trailers. The 2023 model was recently introduced by Living Vehicle and it boasts a few industry firsts.

According to its makers, the off-grid camper is aimed at those who wish “to travel far away from campgrounds and overcrowded RV parks.” With a starting price of $340,000, the luxury camper is available in three versions: Core, Max, and Pro. Additionally, Living Vehicle offers a laundry list of options that can be added to the camper via the company’s online configurator.

Continue reading “This $340,000 fully self-sufficient, off-grid luxury camper is solar-powered and can produce its own water from thin air” »

To meet climate commitments, we need to use more batteries across many economic sectors. Battery analytics can help to remove risk and increase uptake.