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Aug 15, 2016

Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice

Posted by in categories: biotech/medical, genetics, neuroscience

Abstract.

Developmental dyslexia is a common disorder with a strong genetic component, but the underlying molecular mechanisms are still unknown. Several candidate dyslexia-susceptibility genes, including KIAA0319, DYX1C1, and DCDC2, have been identified in humans. RNA interference experiments targeting these genes in rat embryos have shown impairments in neuronal migration, suggesting that defects in radial cortical migration could be involved in the disease mechanism of dyslexia. Here we present the first characterisation of a Kiaa0319 knockout mouse line. Animals lacking KIAA0319 protein do not show anatomical abnormalities in any of the layered structures of the brain. Neurogenesis and radial migration of cortical projection neurons are not altered, and the intrinsic electrophysiological properties of Kiaa0319 -deficient neurons do not differ from those of wild-type neurons. Kiaa0319 overexpression in cortex delays radial migration, but does not affect final neuronal position. However, knockout animals show subtle differences suggesting possible alterations in anxiety-related behaviour and in sensorimotor gating. Our results do not reveal a migration disorder in the mouse model, adding to the body of evidence available for Dcdc2 and Dyx1c1 that, unlike in the rat in utero knockdown models, the dyslexia-susceptibility candidate mouse homolog genes do not play an evident role in neuronal migration. However, KIAA0319 protein expression seems to be restricted to the brain, not only in early developmental stages but also in adult mice, indicative of a role of this protein in brain function. The constitutive and conditional knockout lines reported here will be useful tools for further functional analyses of Kiaa0319.

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Aug 15, 2016

Ancient DNA indicates that the first people in America passed through an entirely different route

Posted by in category: biotech/medical

Our NA ancestors took another route to the Americas?


Recent discoveries, however, suggest otherwise, because it is becoming more evident that humans have already settled in the Americas long before the glaciers became dry, which is around two to three millennia before the final years of the ice age. This means that the ice-free corridor was not viable for these inhabitants to pass through at the time.

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Aug 15, 2016

Funeral Home Offers New DNA Memorial

Posted by in category: biotech/medical

A new way to say good bye to your DNA.


SPRINGFIELD, Ore. — There is a new way to honor your loved one after they pass and it is with a unique memento called “DNA Home Banking”.

Jeff Andreason, owner of Andreason’s Cremation and Buell Funeral Chapel, is the first in Lane County to offer the service.

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Aug 15, 2016

DARPA wants your help to take down drones

Posted by in categories: drones, military, robotics/AI

DARPA recently put out a Request for Information on new ways to protect military forces from small unmanned air systems (sUAS).

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Aug 15, 2016

A Quantum Computing-Dominated World Is Coming In Less Than 10 Years, Says CEO Of Acronis

Posted by in categories: quantum physics, security, solar power, supercomputing, sustainability

I told folks this; I see another one from Google has joined the QC less than 10 year club. My guess is more likely less than 7 years.


A seminal moment in the quantum technology field just happened: Google’s team of scientists have simulated a hydrogen molecule from its quantum computers, a breakthrough that suggests it could “simulate even larger chemical systems,” writes one of Google Quantum’s engineers, Ryan Rabbush. The search engine’s achievement underscores the technology’s potential as Rabbush posits it can “revolutionize the design of solar cells, industrial catalysts, batteries, flexible electronics, medicines, materials and more.”

As advances in such supercomputers continue, investment and research in this field gathers greater momentum as Google, Alibaba, Baidu, Amazon and other tech giants and governments too are racing to develop this technology. Recently, the European Commission allocated €1 billion to research, incubate and invest in quantum technologies. Meanwhile Google last month made headlines about testing its quantum security to shield its Chrome browser.

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Aug 15, 2016

4 Smart Textiles Revolutionizing the Future of Fabric

Posted by in categories: biotech/medical, computing, military, wearables

Luv it; especially fabric to do time release meds, or bio release meds; or do communications via a shirt or jacket.


With the invention of technology-laden fabrics, otherwise known as smart textiles, we are able to benefit from multifunctional materials.

Smart textiles, also known as E-textiles, smart garments, tech fabrics, and smart fabrics, are materials based on technology that integrate advanced features beneficial to the wearer. In an interview with Forbes, Rebeccah Pailes-Friedman, smart textiles and wearable technologies expert stated, “what makes smart fabrics revolutionary is that they have the ability to do many things that traditional fabrics cannot, including communicate, transform, conduct energy and even grow.” And as crazy as it might sound, having computers and technology literally integrated into our clothing is not only acceptable but may one day be the norm.

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Aug 15, 2016

Exclusive Report: The Rise of a More Intelligent Food System

Posted by in category: food

Patrick Keating of Keating International gives an exclusive insight into how the food system has progressed since the earliest forms of agtech.

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Aug 15, 2016

China launches world’s 1st ‘hack-proof’ quantum satellite:The Asahi Shimbun

Posted by in categories: quantum physics, satellites

BLASTOFF! China has launched their new Quantum Satellite today Tuesday. It is the beginning of a whole new tech & communications world.


BEIJING—China on Tuesday launched the world’s first quantum satellite, which will help it establish “hack-proof” communications between space and the ground, state media said, the latest advance in an ambitious space program.

The program is a priority as President Xi Jinping has urged China to establish itself as a space power, and apart from its civilian ambitions, it has tested anti-satellite missiles.

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Aug 15, 2016

China launches ‘hack-proof’ quantum satellite in world first

Posted by in categories: encryption, quantum physics, security, space

This is so exciting.


The transfer of data using quantum communications is considered impenetrable due to a particle phenomenon known as quantum entanglement, with eavesdroppers unable to monitor the transfer without altering the quantum state and thereby being detected. In theory, two parties can communicate in secret by sharing an encryption key encoded in a string of photons.

China’s big-spending quantum research initiative, part of Beijing’s broader multi-billion dollar strategy to overtake the West in science and space research, is being closely watched in global scientific research and security circles, with groups from Canada, Japan, Singapore and Europe also planning their own quantum space experiments.

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Aug 15, 2016

Evidence of Stephen Hawking’s famous prediction about black holes was just observed for the first time

Posted by in categories: cosmology, quantum physics

This nice; however, China’s Quantum Sat. announcement is the big news this morning.


Black holes might not be the bottomless pits we think they are.

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