Lifeboat Foundation

A new discovery explains what determines the number and position of genetic exchanges that occur in sex cells, such as pollen and eggs in plants, or sperm and eggs in humans.

When sex cells are produced by a special cell division called meiosis, chromosomes exchange large segments of DNA. This ensures that each new cell has a unique genetic makeup and explains why, with the exception of identical twins, no two siblings are ever completely genetically alike. These exchanges of DNA, or crossovers, are essential for generating genetic diversity, the driving force for evolution, and their frequency and position along chromosomes are tightly controlled.

Co-first author of the study Dr. Chris Morgan explains the significance of this phenomenon: “Crossover positioning has important implications for evolution, fertility and selective breeding. By understanding the mechanisms that drive crossover positioning we are more likely to be able to uncover methods to modify crossover positioning to improve current plant and animal breeding technologies.”

Following the approval of the consent law by Danish parliament in December 2020, a team of Danish developers released iConsent, which allows users to send a request for consent via their phone to a potential partner, who can then accept or reject the encounter. Via @WIREDUK

Denmark’s iConsent aims to support new sexual consent legislation – but does it lack the sex appeal for everyday use?

After controlling for factors such as age, sex, handedness, first language, education level, and other variables, the researchers found that those who had contracted COVID-19 tended to underperform on the intelligence test compared to those who had not contracted the virus. The greatest deficits were observed on tasks requiring reasoning, planning and problem solving, which is in line “with reports of long-COVID, where ‘brain fog,’ trouble concentrating and difficulty finding the correct words are common,” the researchers said.

People who have recovered from COVID-19 tend to score significantly lower on an intelligence test compared to those who have not contracted the virus, according to new research published in The Lancet journal EClinicalMedicine. The findings suggest that the SARS-CoV-2 virus that causes COVID-19 can produce substantial reductions in cognitive ability, especially among those with more severe illness.

“By coincidence, the pandemic escalated in the United Kingdom in the middle of when I was collecting cognitive and mental health data at very large scale as part of the BBC2 Horizon collaboration the Great British Intelligence Test,” said lead researcher Adam Hampshire (@HampshireHub), an associate professor in the Computational, Cognitive and Clinical Neuroimaging Laboratory at Imperial College London.

Continue reading “Large study finds COVID-19 is linked to a substantial deficit in intelligence” »

“In this study, for the first time, we see evidence that events which were always assumed to be occurring in the same manner, regardless of sex, may actually be completely different in males compared to females. The fact that these differences involve astrocytes, which have traditionally been ignored in neuroscience but have recently become a hot topic for study, makes them all the more intriguing.”

Summary: Thrombospondin-2, a protein with cell adhesion properties usually secreted by astrocytes, prompted a strong increase in synapses in male-derived neurons but showed no effect in females.

Source: Marshall University

Continue reading “Non-Neuronal Cells Drive Sex Differences in Early Brain Development” »

Universe Today.

Space may be pretty, but it’s dangerous. Astronauts face a much higher dose of ionizing radiation than us Earth-bound folks, and a new report says that NASA’s current guidelines and risk assessment methods are in serious need of an update.

On the surface of the Earth, protected by our extensive magnetic field and layers of thick atmosphere, we experience about 2–3 milliSieverts (mSv) of radiation exposure every year. Even that background level is enough to trigger the occasional cancer growth.

Continue reading “Report Suggests That Astronauts Shouldn’t get More Than 600 Millisieverts of Radiation Exposure During Their Career. We get 2-3 a Year Down Here on Earth” »

This video explains x-linked traits/sex linked traits and thomas hunt morgan experiment.

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There are Sirt6 activators on the market, but since we are not seeing any major news about results I would question their value.

SPONSOR: Longevity. Technology — https://www.longevity.technology/?utm_source=SSS&utm_medium=…aign=Sirt6

Continue reading “The longevity sirtuin – what you need to know about SIRT6” »

Wines and table grapes exist thanks to a genetic exchange so rare that it’s only happened twice in nature in the last 6 million years. And since the domestication of the grapevine 8000 years ago, breeding has continued to be a gamble.

When today’s growers cultivate new varieties – trying to produce better-tasting and more disease-resistant grapes – it takes two to four years for breeders to learn whether they have the genetic ingredients for the perfect flower.

Females set fruit, but produce sterile pollen. Males have stamens for pollen, but lack fruit. The perfect flower, however, carries both sex genes and can self-pollinate. These hermaphroditic varieties generally yield bigger and better-tasting berry clusters, and they’re the ones researchers use for additional cross-breeding.

Skin aging is a multifactorial process consisting of two distinct and independent mechanisms: intrinsic and extrinsic aging. Youthful skin retains its turgor, resilience and pliability, among others, due to its high content of water. Daily external injury, in addition to the normal process of aging, causes loss of moisture. The key molecule involved in skin moisture is hyaluronic acid (HA) that has unique capacity in retaining water. There are multiple sites for the control of HA synthesis, deposition, cell and protein association and degradation, reflecting the complexity of HA metabolism. The enzymes that synthesize or catabolize HA and HA receptors responsible for many of the functions of HA are all multigene families with distinct patterns of tissue expression. Understanding the metabolism of HA in the different layers of the skin and the interactions of HA with other skin components will facilitate the ability to modulate skin moisture in a rational manner.

Keywords: hyaluronic acid, hyaluronic acid synthases, hyaluronidases, CD44, RHAMM, skin aging.

Human skin aging is a complex biological process, not yet fully understood. It is the result of two biologically independent processes. The first is intrinsic or innate aging, an unpreventable process, which affects the skin in the same pattern as it affects all internal organs. The second is extrinsic aging, which is the result of exposure to external factors, mainly ultraviolet (UV) irradiation, that is also referred to as photoaging.¹ Intrinsic skin aging is influenced by hormonal changes that occur with age,² such as the gradual decreased production of sex hormones from the mid-twenties and the diminution of estrogens and progesterone associated with menopause. It is well established that the deficiency in estrogens and androgens results in collagen degradation, dryness, loss of elasticity, epidermal atrophy and wrinkling of the skin.³