Lifeboat Foundation

Jumping genes — not jumping beans.

“Jumping genes” are ubiquitous. Every domain of life hosts these sequences of DNA that can “jump” from one position to another along a chromosome; in fact, nearly half the human genome is made up of jumping genes. Depending on their specific excision and insertion points, jumping genes can interrupt or trigger gene expression, driving genetic mutation and contributing to cell diversification. Since their discovery in the 1940s, researchers have been able to study the behavior of these jumping genes, generally known as transposons or transposable elements (TE), primarily through indirect methods that infer individual activity from bulk results. However, such techniques are not sensitive enough to determine precisely how or why the transposons jump, and what factors trigger their activity.

Reporting in the Proceedings of the National Academy of Sciences, scientists at the University of Illinois at Urbana-Champaign have observed jumping gene activity in real time within living cells. The study is the collaborative effort of physics professors Thomas Kuhlman and Nigel Goldenfeld, at the Center for the Physics of Living Cells, a National Science Foundation Physics Frontiers Center.

Continue reading “Watching ‘jumping genes’ in action” »

Gerard K. O’Neill’s name might not ring a bell for many of us, but he certainly is one of the most significant names in the world of physics and space sciences. Gerard was an American physicist whose ideologies resonated with the concept of Space Manufacturing and Space Colonization as early as 1969.

He visualized establishment of a space manufacturing facility that would product end products for use in the outer space. Located in a very high orbit as compared to Earth, or on any celestial body, he claimed that the manufacturing facility would be self-sufficient and would be built entirely using materials available on celestial surfaces like lunar soil. When O’Neill presented his novel idea using research papers at different forums, he faced rejection and disapproval as every other world-changing idea did.

Continue reading “The obvious connection between 3D Printing and Space Colonization” »

This is the only way out of the trap this universe puts on your brain.

For every star performing biotech, life sciences or innovative 3D printing company there are another 9 where investors would have been better off keeping their cash under a mattress.

As Organovo report their first full year operating on a commercial basis we look for clues as to which category they might fit into. With more than 25 patents secured and another 80 pending, does the current share price and today’s published financial accounts tell the full story?

Organovo increased total revenue from $570 thousand in 2015 to $1.5 million for 2016. However, losses also increased from $30.8 million to $38.6 million. Although yet to turn a profit, Organovo were always going to generate a sizeable amount of text in the 3D Printing media and beyond. The promise of combining biophysics, developmental biology and of course 3D printing to advance healthcare and life sciences is an attractive proposition.

Continue reading “3D bioprinting Pioneer Organovo Announce 2016 financial results” »

Theoretical physicists have confirmed that it’s not just the information coded into our DNA that shapes who we are — it’s also the way DNA folds itself that controls which genes are expressed inside our bodies.

That’s something biologists have known for years, and they’ve even been able to figure out some of the proteins responsible for folding up DNA. But now a group of physicists have been able to demonstrate for the first time through simulations how this hidden information controls our evolution.

Let’s back up for a second here, because although it’s not necessarily news to many scientists, this second level of DNA information might not be something you’re familiar with.

Continue reading “Physicists confirm there’s a second layer of information hidden in our DNA” »

Edwin E Klingman, klingman@geneman.com

PO Box 3000, San Gregorio CA 94074

Abstract.

Continue reading “Fundamental Physics of Consciousness” »

The fact that the speed of light in a vacuum is a constant is one of the cornerstones of physics, but scientists from the Philippines were able to add a twist to this tenet. And I mean it literally!

By changing how some light beams rotate, the researchers from the National Institute of Physics were able to slow down light in a vacuum. The physicists used circularly symmetric light beams, known as Laguerre-Gauss beams, to change the way light twists around itself. Suddenly, the light beams were propagating more slowly.

The speed of light varies when it moves through different materials, and it does so at the expense of accuracy in transmitting information. For this reason, more and more people are interested in ways of manipulating the speed of light without affecting accuracy.

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Researchers from Moscow Institute of Physics and Technology (MIPT), and the University of Milan have experimentally confirmed a model to detect electron delocalization in molecules and crystals.

A 3D hydrogel biochip, a new way of detecting colorectal cancer in the early stages, has been discovered by the scientists at the Moscow Institute of Physics and Technology. The announcement was made in time for the upcoming conference of the annual American Society of Clinical Oncology.

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The 3D hydrogel biochip will be using antibodies to determine the CRC specific glycans that emerge in the earliest stages of cancer, with the hope of improving today’s survival rates. These biochips are 3D cells consisting of a special gel that has molecular probes. Based on reports, the physical feature of the gel is an optimal form for running tests. The Russian scientists were able to develop a method that can calculate the concentration of antibodies-to-glycans in the patient’s blood. This means that combining the biochips into a patient’s blood sample will give the mot precise results.

Continue reading “Cancer Treatment Update: 3D Hydrogel Biochip To Help Increase Colorectal Cancer Survival” »