Lifeboat Foundation

Imagine a future technology that would provide instant access to the world’s knowledge and artificial intelligence, simply by thinking about a specific topic or question. Communications, education, work, and the world as we know it would be transformed.

Writing in Frontiers in Neuroscience, an international collaboration led by researchers at UC Berkeley and the US Institute for Molecular Manufacturing predicts that exponential progress in nanotechnology, nanomedicine, AI, and computation will lead this century to the development of a “Human Brain/Cloud Interface” (B/CI), that connects brain cells to vast cloud-computing networks in real time.

The Internet comprises a decentralized global system that serves humanity’s collective effort to generate, process, and store data, most of which is handled by the rapidly expanding cloud. A stable, secure, real-time system may allow for interfacing the cloud with the human brain. One promising strategy for enabling such a system, denoted here as a “human brain/cloud interface” (“B/CI”), would be based on technologies referred to here as “neuralnanorobotics.” Future neuralnanorobotics technologies are anticipated to facilitate accurate diagnoses and eventual cures for the ∼400 conditions that affect the human brain. Neuralnanorobotics may also enable a B/CI with controlled connectivity between neural activity and external data storage and processing, via the direct monitoring of the brain’s ∼86 × 10 neurons and ∼2 × 10¹⁴ synapses. Subsequent to navigating the human vasculature, three species of neuralnanorobots (endoneurobots, gliabots, and synaptobots) could traverse the blood–brain barrier (BBB), enter the brain parenchyma, ingress into individual human brain cells, and autoposition themselves at the axon initial segments of neurons (endoneurobots), within glial cells (gliabots), and in intimate proximity to synapses (synaptobots). They would then wirelessly transmit up to ∼6 × 10¹⁶ bits per second of synaptically processed and encoded human–brain electrical information via auxiliary nanorobotic fiber optics (30 cm) with the capacity to handle up to 10¹⁸ bits/sec and provide rapid data transfer to a cloud based supercomputer for real-time brain-state monitoring and data extraction. A neuralnanorobotically enabled human B/CI might serve as a personalized conduit, allowing persons to obtain direct, instantaneous access to virtually any facet of cumulative human knowledge. Other anticipated applications include myriad opportunities to improve education, intelligence, entertainment, traveling, and other interactive experiences. A specialized application might be the capacity to engage in fully immersive experiential/sensory experiences, including what is referred to here as “transparent shadowing” (TS). Through TS, individuals might experience episodic segments of the lives of other willing participants (locally or remote) to, hopefully, encourage and inspire improved understanding and tolerance among all members of the human family.

“We’ll have nanobots that… connect our neocortex to a synthetic neocortex in the cloud… Our thinking will be a… biological and non-biological hybrid.”

— Ray Kurzweil, TED 2014

Continue reading “Human Brain/Cloud Interface” »

Plants are naturally amazing little machines – so giving them a bionic leg-up could unlock a whole new range of abilities. Now a team of researchers from the University of Melbourne has developed a new way to turn plants into nanomaterial factories, which could allow them to act as chemical sensors or even allow them to survive in harsh environments, such as in space or on Mars.

A fringe group of scientists and tech moguls think they’re closing in on the fountain of youth. Here’s everything you need to know:

What is biohacking? Silicon Valley is built on the idea that technology can optimize, or “hack,” any aspect of our lives — so why not the human life span? Until recently, anyone hawking pills or treatments that promised to restore youthfulness was considered a quack, yet a growing number of “transhumanists” are convinced that, in time, human beings can be transformed through bioengineering, and that aging will be curable just like any other malady.

In light of rapid gains in gene editing, nanotechnology, and robotics, some futurists expect this generation’s biohackers to double their life spans. Aubrey de Grey, a regenerative medicine researcher backed by tech mogul Peter Thiel, insists that someone alive today will live to be 1,000. “It’s extraordinary to me that it’s such an incendiary claim,” de Grey says. Korean physician and financier Joon Yun has offered two $500,000 prizes to anyone who can restore a test animal’s youthful heart rate and extend its lifespan by 50 percent. For humans, the mortality rate at age 20 is 0.001 percent, Yun figures, “so if you could maintain the homeostatic capacity of that age throughout your life, your average life span would be 1,000.”

A team of researchers from Nanjing and Xiamen Universities in China has developed an alternative to using viruses to transport CRISPR-Cas9 gene editing tools into a desired cell—and it involves two types of light. In their paper published in the journal Science Advances, the group describes their new type of carrier and how well it worked with test mice.

CRISPR-Cas9 gene editing tools are a coming revolution in treating genetic conditions, and scientists continue to test their abilities in a variety of applications. One area of study has involved looking for a replacement carrier system—the current approach uses a virus to carry the gene editing tool into a particular cell. Early on, researchers knew that the virus approach was not viable because of possible responses from the immune system, or worse, the threat of initiating tumors. In this new effort, the team in China has come up with an entirely new way to deliver the gene editing tool using two kinds of light.

Their carrier system consists of nanoparticles that are sensitive to low-energy near–infrared radiation (NIR) and that emit UV light. When NIR is shone on the nanoparticles, the light is absorbed and converted to UV light, which is emitted. Inside of a cell, the package is activated by shining NIR onto the skin, where it penetrates into the body and makes its way to the gene editing tool. When the NIR is converted to UV light, it cuts molecules in the carrier package, releasing the gene editing tool to do its work.

Continue reading “A light-based carrier system for CRISPR-Cas9 gene editing” »

A University of California Irvine student may have stumbled upon an invention to end your phone-charging woes for good. And that’s just the tip of the iceberg of where that could take us as a society. Forget about your phone; the world would be a different place without ever having to worry about replacing car batteries, and imagine the uses that it could have in space exploration. Technology is the ultimate wildcard.

A battery that lasts a whole lifetime is now one step closer to becoming a reality thanks to Mya Le Thai, a PhD student who’s been researching how to make better nanowire rechargeable batteries. In theory, her discovery could lead to a battery that lasts centuries—as long as 400 years.

Continue reading “UCI Student ‘Accidentally’ Invents a Rechargeable Battery That Lasts 400 Years” »

When a particle is completely isolated from its environment, the laws of quantum physics start to play a crucial role. One important requirement to see quantum effects is to remove all thermal energy from the particle motion, i.e. to cool it as close as possible to absolute zero temperature. Researchers at the University of Vienna, the Austrian Academy of Sciences and the Massachusetts Institute of Technology (MIT) are now one step closer to reaching this goal by demonstrating a new method for cooling levitated nanoparticles. They now publish their results in the renowned journal Physical Review Letters.

Tightly focused laser beams can act as optical “tweezers” to trap and manipulate tiny objects, from glass particles to living cells. The development of this method has earned Arthur Ashkin the last year’s Nobel prize in physics. While most experiments thus far have been carried out in air or liquid, there is an increasing interest for using optical tweezers to trap objects in ultra-high vacuum: such isolated particles not only exhibit unprecedented sensing performance, but can also be used to study fundamental processes of nanoscopic heat engines, or quantum phenomena involving large masses.

A key element in these research efforts is to obtain full control over the particle motion, ideally in a regime where the laws of quantum physics dominate its behavior. Previous attempts to achieve this, have either modulated the optical tweezer itself, or immersed the particle into additional light fields between highly reflecting mirror configurations, i.e. optical cavities.

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UC Berkeley chemists have proved that three carbon structures recently created by scientists in South Korea and Japan are in fact the long-sought schwarzites, which researchers predict will have unique electrical and storage properties like those now being discovered in buckminsterfullerenes (buckyballs or fullerenes for short), nanotubes and graphene.

The new structures were built inside the pores of zeolites, crystalline forms of silicon dioxide – sand – more commonly used as water softeners in laundry detergents and to catalytically crack petroleum into gasoline. Called zeolite-templated carbons (ZTC), the structures were being investigated for possible interesting properties, though the creators were unaware of their identity as schwarzites, which theoretical chemists have worked on for decades.

Continue reading “Schwarzites: Long-sought carbon structure joins graphene, fullerene family” »

E-mail address: saad.khan@utsouthwestern.edu

https://orcid.org/0000-0002-3440-9774

Department of internal medicine, UT southwestern medical center, dallas, texas.