Lifeboat Foundation

Cross posted from Next big future

Since a journal article was submitted to the Royal Society of Chemistry, the U of Alberta researchers have already made the processor and unit smaller and have brought the cost of building a portable unit for genetic testing down to about $100 Cdn. In addition, these systems are also portable and even faster (they take only minutes). Backhouse, Elliott and McMullin are now demonstrating prototypes of a USB key-like system that may ultimately be as inexpensive as standard USB memory keys that are in common use – only tens of dollars. It can help with pandemic control and detecting and control tainted water supplies.

This development fits in with my belief that there should be widespread inexpensive blood, biomarker and genetic tests to help catch disease early and to develop an understanding of biomarker changes to track disease and aging development. We can also create adaptive clinical trials to shorten the development and approval process for new medical procedures

The device is now much smaller than size of a shoe-box (USB stick size) with the optics and supporting electronics filling the space around the microchip

Continue reading “Cheap (tens of dollars) genetic lab on a chip systems could help with pandemic control” »

Reposted from Next Big Future which was advancednano.

A 582,970 base pair sequence of DNA has been synthesized.

It’s the first time a genome the size of a bacterium has chemically been synthesized that’s about 20 times longer than [any DNA molecule] synthesized before.

This is a huge increase in capability. It has broad implications for DNA nanotechnology and synthetic biology.

Continue reading “On the brink of Synthetic Life: DNA synthesis has increased twenty times to full bacteria size” »

In his most recent paper “Reducing the Risk of Human Extinction,” SAB member Jason G. Matheny approached the topic of human extinction from what is unfortunately a somewhat unusual angle. Jason examined the cost effectiveness of preventing humanity’s extinction due to a catastrophic asteroid impact.

Even with some rather pessimistic assumptions, his calculations showed a pretty convincing return on investment. For only about US$ 2.50 per life year saved, Matheny predicts that we could mitigate the risk of humanity being killed off by a large asteroid. Maybe it’s just me, but it sounds pretty compelling.

Matheny also made a very good point that we all should ponder when we consider how our charitable giving and taxes gets spent. “We take extraordinary measures to protect some endangered species from extinction. It might be reasonable to take extraordinary measures to protect humanity from the same.”

For more coverage on this important paper please see the October 2007 issue of Risk Analysis and a recent edition of Nature News.

In a recent conversation on our discussion list, Ben Goertzel, a rising star in artificial intelligence theory, expressed skepticism that we could keep a “modern large-scale capitalist representative democracy cum welfare state cum corporate oligopoly” going for much longer.

Indeed, our complex civilization currently does seem to be under a lot of stress.

Lifeboat Foundation Scientific Advisory Board member and best-selling author David Brin’s reply was quite interesting.

David writes:

Continue reading “The Enlightenment Strikes Back” »

Planning for the first Lifeboat Foundation conference has begun. This FREE conference will be held in Second Life to keep costs down and ensure that you won’t have to worry about missing work or school.

While an exact date has not yet been set, we intend to offer you an exciting line up of speakers on a day in the late spring or early summer of 2008.

Several members of Lifeboat’s Scientific Advisory Board (SAB) have already expressed interest in presenting. However, potential speakers need not be Lifeboat Foundation members.

If you’re interested in speaking, want to help, or you just want to learn more, please contact me at matt@lifeboat.com.

What’s the NanoShield you ask? It’s a long-term scientific research project aimed at creating a nanotechnoloigical immune system. You can learn more about it here.

Facebook users — please come join the cause and help fund the Lifeboat Foundation’s NanoShield project.

Not a Facebook user? No worries. By joining the Lifeboat Foundation and making even a small donation you can have a hugely positive impact on humanity’s future well being.

So why not join us?

The inspiration of Help Hookup is actually a comic book called Global Frequency by Warren Ellis. My brother, Alvin Wang, took the idea to startup weekend and they launched the idea this past weekend for hooking up volunteers. It is similar to the concepts of David Brin’s “empowered citizens” and Glenn Reynolds “an army of Davids”. The concepts are compatible with the ideas and causes of the Lifeboat foundation.

Global Frequency was a network of 1,001 people that handled the jobs that the governments did not have the will to handle. I thought that it was a great idea and it would be more powerful with 1,000,001 people or 100,000,001 people. We would have to leave out the killing that was in the comic.

Typhoons, earthquakes, and improperly funded education could all be handled. If there is a disaster, doctors could volunteer. Airlines could provide tickets. Corporations could provide supples. Trucking companies could provide transportation. Etc. State a need, meet the need. No overhead. No waste.

The main site is here it is a way for volunteers to hookup

The helphookup blog is tracking the progress.

University of Pittsburgh researchers injected a therapy previously found to protect cells from radiation damage into the bone marrow of mice, then dosed them with some 950 roentgens of radiation — nearly twice the amount needed to kill a person in just five hours. Nine in 10 of the therapy-receiving mice survived, compared to 58 percent of the control group.

Between 30 and 330 days, there were no differences in survival rates between experiment and control group mice, indicating that systemic MnSOD-PL treatment was not harmful to survival.

The researchers will need to verify whether this treatment would work in humans.

This is part of the early development in the use of genetic modification to increase the biological defences (shields) of people against nuclear, biological and chemical threats. We may not be able to prevent all attacks, so we should improve our toughness and survivability. We should still try to stop the attacks and create the conditions for less attacks.

Robert Freitas, Jr., Lifeboat Foundation Fellow and head of the Lifeboat Foundation’s Nanomedicine Division has won the 2007 Foresight Institute Feynman Prize in Communication.

Dr. Pearl Chin, President of the Foresight Nanotech Institute, said Freitas received the award for “pioneering the study and communication of the benefits to be obtained from an advanced nanomedicine that will be made possible by molecular manufacturing [and for having] worked to develop and communicate a path from our current technology base to a future technology base that will enable advanced nanomedicine.”

Prior to his Feynman Prize win Robert shared the Lifeboat Foundation’s 2006 Guardian Award with technology legend Bill Joy. Freitas and Joy shared the Guardian award for their many years of work on mitigating risks posed by advanced technologies.