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Archive for the ‘life extension’ category: Page 599

May 9, 2016

This vitamin stops the aging process in organs, say Swiss researchers

Posted by in categories: biotech/medical, life extension

Improved muscle stem cell numbers and muscle function in NR-treated aged mice: Newly regenerated muscle fibers 7 days after muscle damage in aged mice (left: control group; right: fed NR). (Scale bar = 50 μm). (credit: Hongbo Zhang et al./Science)

EPFL researchers have restored the ability of mice organs to regenerate and extend life by simply administering nicotinamide riboside (NR) to them.

NR has been shown in previous studies to be effective in boosting metabolism and treating a number of degenerative diseases. Now, an article by PhD student Hongbo Zhang published in Science also describes the restorative effects of NR on the functioning of stem cells for regenerating organs.

Continue reading “This vitamin stops the aging process in organs, say Swiss researchers” »

May 6, 2016

Japanese scientists have used skin cells to restore a patient’s vision for the first time

Posted by in categories: biotech/medical, life extension

Japanese scientists have reported the first successful skin-to-eye stem cell transplant in humans, where stem cells derived from a patient’s skin were transplanted into her eye to partially restore lost vision.

The patient, a 70-year-old woman diagnosed with age-related macular degeneration (AMD) – the leading cause of vision impairment in older people – received the experimental treatment back in 2014 as part of a pilot study. Now, closing in on two years after the transplant took place, the scientists are sharing the results.

The researchers took a small piece of skin from her arm (4 mm in diameter) and modified its cells, effectively reprogramming them into induced pluripotent stem cells (iPSC).

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May 6, 2016

The transhumanist presidential candidate wants you to live forever

Posted by in categories: geopolitics, life extension, transhumanism

New story and video on transhumanism from Vocativ:


His name is Zoltan Istvan, and he’s running on the Transhumanist ticket.

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May 5, 2016

The End of Aging? Soon It Might Be a Prescription Away

Posted by in categories: biological, Elon Musk, life extension

They are worth 6 billion dollars.


They are calling him the Elon Musk of biology. But will we see an end to aging soon?

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May 4, 2016

The surprising way Transhumanist Zoltan Istvan could make it to the White House

Posted by in categories: life extension, transhumanism

Interesting article by CNET, the leading tech site in traffic, on how a strong science, longevity, and technology platform could end up in Washington in 2016:


CNET exclusive: The only pro-immortality candidate could eventually team up with one of the big names in the race.

Read more

May 4, 2016

Biogen haemophilia spin-out to develop gene therapies and long-acting factors

Posted by in categories: business, life extension

The new entity will focus on a haemophilia pipeline utilising the XTEN half-life extension technology, bispecific antibodies and gene therapies.

Biogen announced yesterday it is planning to spin-out its haemophilia business into an independent, public firm based in Boston, Massachusetts by early next year.

Management said during a conference call this was the right time for a spin-out as Biogen’s haemophilia business has matured.

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May 2, 2016

Adult brain prunes branched connections of new neurons

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

When tweaking its architecture, the adult brain works like a sculptor—starting with more than it needs so it can carve away the excess to achieve the perfect design. That’s the conclusion of a new study that tracked developing cells in an adult mouse brain in real time.

New began with a period of overgrowth, sending out a plethora of neuronal branches, before the brain pruned back the connections. The observation, described May 2, 2016 in Nature Neuroscience, suggests that new cells in the have more in common with those in the embryonic brain than scientists previously thought and could have implications for understanding diseases including autism, intellectual disabilities and schizophrenia.

“We were surprised by the extent of the pruning we saw,” says senior author Rusty Gage, a professor in Salk’s Laboratory of Genetics and holder of the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease.

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May 2, 2016

10 responses to “Hacking Aging”

Posted by in categories: biotech/medical, law, life extension, mathematics

What would you say if I told you that aging happens not because of accumulation of stresses, but rather because of the intrinsic properties of the gene network of the organism? I’m guessing you’d be like: surprised .

So, here’s the deal. My biohacker friends led by Peter Fedichev and Sergey Filonov in collaboration with my old friend and the longevity record holder Robert Shmookler Reis published a very cool paper. They proposed a way to quantitatively describe the two types of aging – negligible senescence and normal aging. We all know that some animals just don’t care about time passing by. Their mortality doesn’t increase with age. Such negligibly senescent species include the notorious naked mole rat and a bunch of other critters like certain turtles and clams to name a few. So the paper explains what it is exactly that makes these animals age so slowly – it’s the stability of their gene networks.

What does network stability mean then? Well, it’s actually pretty straightforward – if the DNA repair mechanisms are very efficient and the connectivity of the network is low enough, then this network is stable. So, normally aging species, such as ourselves, have unstable networks. This is a major bummer by all means. But! There is a way to overcome this problem, according to the proposed math model.

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May 2, 2016

Raytheon developing technology to make software “immortal”

Posted by in categories: computing, engineering, life extension, military

Making software immortal; Raytheon is trying to make it a reality.


CAMBRIDGE, Mass., May 2, 2016 /PRNewswire/ — A team led by Raytheon BBN Technologies is developing methods to make mobile applications viable for up to 100 years, despite changes in hardware, operating system upgrades and supporting services. The U.S. Air Force is sponsoring the four-year, $7.8 million contract under the Defense Advanced Research Projects Agency’s Building Resource Adaptive Software Systems program.

“Mobile apps are pervasive in the military, but frequent operating system upgrades, new devices and changing missions and environments require manual software engineering that is expensive and causes unacceptable delays,” said Partha Pal, principal scientist at Raytheon BBN. “We are developing techniques to eliminate these interruptions by identifying the way these changes affect application functionality and modifying the software.”

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May 2, 2016

How AI will make information akin to electricity

Posted by in categories: biotech/medical, computing, engineering, government, internet, life extension, mathematics, mobile phones, robotics/AI, wearables

Ask an Information Architect, CDO, Data Architect (Enterprise and non-Enterprise) they will tell you they have always known that information/ data is a basic staple like Electricity all along; and glad that folks are finally realizing it. So, the same view that we apply to utilities as core to our infrastructure & survival; we should also apply the same value and view about information. And, in fact, information in some areas can be even more important than electricity when you consider information can launch missals, cure diseases, make you poor or wealthy, take down a government or even a country.


What is information? Is it energy, matter, or something completely different? Although we take this word for granted and without much thought in today’s world of fast Internet and digital media, this was not the case in 1948 when Claude Shannon laid the foundations of information theory. His landmark paper interpreted information in purely mathematical terms, a decision that dematerialized information forever more. Not surprisingly, there are many nowadays that claim — rather unthinkingly — that human consciousness can be expressed as “pure information”, i.e. as something immaterial graced with digital immortality. And yet there is something fundamentally materialistic about information that we often ignore, although it stares us — literally — in the eye: the hardware that makes information happen.

As users we constantly interact with information via a machine of some kind, such as our laptop, smartphone or wearable. As developers or programmers we code via a computer terminal. As computer or network engineers we often have to wade through the sheltering heat of a server farm, or deal with the material properties of optical fibre or copper in our designs. Hardware and software are the fundamental ingredients of our digital world, both necessary not only in engineering information systems but in interacting with them as well. But this status quo is about to be massively disrupted by Artificial Intelligence.

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