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Archive for the ‘life extension’ category: Page 521

Oct 17, 2017

Hallmarks of Aging: Epigenetic Alterations

Posted by in categories: biotech/medical, genetics, life extension

This is the second part of our ongoing series of articles that discuss the Hallmarks of Aging. Published in 2013, the paper divides aging into a number of distinct categories (“hallmarks”) of damage to explain how the aging process works and how it causes age-related diseases[1].

Today, we will be looking at one of the primary hallmarks, epigenetic alterations.

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Oct 17, 2017

The Epigenome in Cancer and Disease

Posted by in categories: biotech/medical, genetics, life extension

Describes the epigenetic role in aging, cancer and disease as well as drugs that are targeting the epigenome.


Our epigenome plays a role in aging and also in diseases like cancer and diabetes. Scientists have developed epigenome-targeting cancer drugs.

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Oct 16, 2017

Yes, people do not like to admit it which is a serious barrier to acknowledging we should be doing something about it

Posted by in category: life extension

How did you come to accept that aging was a problem?

#CrowdfundTheCure for #aging at www.lifespan.io

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Oct 16, 2017

A Healthy Aged Gut Is Similar to a Healthy Young Gut

Posted by in categories: biotech/medical, life extension

The topic of the gut microbiota is increasingly in the news of late, and its connection with chronic age-related inflammation, known as inflammaging, is becoming increasingly clear.

What is the microbiota?

The microbiota describes the community of symbiotic and pathogenic microorganisms that live in and on all multicellular organisms, and it includes bacteria, archaea, protists, fungi, and viruses. In particular, the gut microbiota and its role in aging and disease have increasingly become of interest to researchers in recent years.

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Oct 16, 2017

‘Postbiological’ alien civilisation that survives using AI could exist

Posted by in categories: alien life, life extension, robotics/AI

Are AI aliens watching Earth? An immortal machine civilization could already exist and may be BILLIONS of years old, leading expert claims…


Artificial intelligence could already exist elsewhere in the universe and may have been around for billions of years, according to a leading expert.

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Oct 15, 2017

Can We Rejuvenate Our Bodies Using Telomerase to Lengthen Telomeres?

Posted by in categories: biotech/medical, life extension

Telomerase replenishes telomeres, extending the cell’s lifespan. Researchers hope that telomerase enhancement will rejuvenate our organs.

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Oct 15, 2017

New Senolytics Reverse Aging

Posted by in categories: biotech/medical, life extension

Senolytics have been a hot topic lately. Here’s a primer.


Senolytics reverse aging by killing senescent cells. Researchers have found seven senolytics and are testing them in clinical trials.

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Oct 14, 2017

Can We Reverse Stem Cell Decline and Rejuvenate Our Bodies? (Part 2)

Posted by in categories: biotech/medical, life extension

Last article (3 of 3) in three part stem cell series.


Stem cell decline goes with aging. With the right growth factors, we can awaken our lazy stem cells to repair our aging organs.

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Oct 14, 2017

Can We Reverse Stem Cell Decline and Rejuvenate Our Bodies? (Part 1)

Posted by in categories: biotech/medical, life extension

Second article (#2 of 3) in three part stem cell series.


Summary: Stem cell decline leads to disease, gradual organ failure, and death. Learn what causes it and how researchers are trying to reverse stem cell decline. Part one of a two-part series.

Are stem cells the fountain of youth?

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Oct 14, 2017

Cellular Garb-aging Causes You To Age (Loss of proteostasis)

Posted by in categories: biotech/medical, life extension

Cellular Garb-aging is the build-up of junk inside the cells that naturally occurs during aging. This article says why it happens.


To maintain protein homeostasis, and prevent garb-aging, the cell uses molecular chaperones, which help assemble and disassemble proteins. Chaperonins are a special class of chaperones that provide favorable conditions for the correct folding of other proteins, thus preventing aggregation. Chaperonins prevent the misfolding of proteins, which prevents conditions such as Mad Cow Disease. Sometimes, chaperonin proteins may also tag misfolded proteins to be degraded. When properly tagged, other processes can recognize the damaged or misfolded proteins and ‘take out the trash.’

Think of it as garb-aging removal.

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