Archive for the ‘life extension’ category: Page 220
Nov 21, 2020
An Interview with David Ettinger on the Cryonics Institute (Detroit)
Posted by Tanvir Ahmed in categories: cryonics, life extension, media & arts
Nov 20, 2020
Can damage repair give us indefinite youth? | Dr Aubrey de Grey
Posted by John Davies in categories: biotech/medical, law, life extension
In the third episode of the Healthy Longevity webinar series, we hear from Dr Aubrey de Grey, Chief Science Officer of the SENS Research Foundation as he joins Prof Brian Kennedy for a science-backed and inspirational conversation on regenerative medicine and the implications of a population that lives longer and in good health.
Register for upcoming webinar episodes here: https://bit.ly/3jhe0SB.
Continue reading “Can damage repair give us indefinite youth? | Dr Aubrey de Grey” »
Nov 20, 2020
It Sure Looks Like Humans Have Found a Way to Reverse Aging
Posted by Quinn Sena in categories: bioengineering, biotech/medical, life extension
A landmark study shows this age-old tech is the key.
The cure for aging has long been the Holy Grail of medicine. Emerging technologies, like the gene editing tool CRISPR, have opened the floodgates to what may be possible for the future of medical science. The key to slowing down aging, however, may lie in a simple and age-old technique.
Dive deeper. ➡ Read best-in-class health, tech, and science features, and get unlimited access to Pop Mech.
Continue reading “It Sure Looks Like Humans Have Found a Way to Reverse Aging” »
Nov 20, 2020
Getting it just right: The Goldilocks model of cancer
Posted by Kevin Huang in categories: biotech/medical, chemistry, genetics, life extension
Senescence in cancer cells
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Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a type of cellular aging that actually results in arrested growth. Scientists at Duke-NUS Medical School have now discovered that a well-known signaling pathway helps cancers grow by blocking the pro-growth signals from a second major cancer pathway.
Continue reading “Getting it just right: The Goldilocks model of cancer” »
Nov 20, 2020
Hybrid 3D-printing bioinks help repair damaged knee cartilage
Posted by Raphael Ramos in categories: 3D printing, bioprinting, biotech/medical, life extension
This may be good news for those who have damaged joints due to sports or old age.
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Human knees are notoriously vulnerable to injury or wearing out with age, often culminating in the need for surgery. Now researchers have created new hybrid bioinks that can be used to 3D print structures to replace damaged cartilage in the knee.
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Nov 19, 2020
Near-infrared probe decodes telomere dynamics
Posted by Kevin Huang in categories: biotech/medical, chemistry, life extension
A new synthetic probe offers a safe and straightforward approach for visualizing chromosome tips in living cells. The probe was designed by scientists at the Institute for Integrated Cell-Material Science (iCeMS) and colleagues at Kyoto University, and could advance research into aging and a wide range of diseases, including cancers. The details were published in the Journal of the American Chemical Society.
“Chromosome ends are constantly at risk of degradation and fusion, so they are protected by structures called telomeres, which are made of long repeating DNA sequences and bound proteins,” says iCeMS chemical biologist Hiroshi Sugiyama, who led the study. “If telomeres malfunction, they are unable to maintain chromosome stability, which can lead to diseases such as cancer. Also, telomeres normally shorten with each cell division until they reach their limit, causing cell death.”
Visualizing telomeres, especially their physical arrangements in real-time, is important for understanding their relevance to disease and aging. Several visualization approaches already exist, but they have disadvantages. For example, some can only observe telomeres in preserved, or fixed, cells. Others are time-consuming or involve harsh treatments that denature DNA.
Nov 18, 2020
Hyperbaric Oxygen Therapy: First Human Study Shows Reversal in Biology of Aging
Posted by Nicholi Avery in categories: biotech/medical, life extension
TEL AVIV — November 18, 2020: In a scientifically verified approach, signalling an important breakthrough in the study of aging, Tel Aviv University and The Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center announced today that, for the first time in humans, two key biological hallmarks of aging, telomere length shortening, and accumulation of senescent cells, can be reversed. The prospective clinical trial, published in peer-reviewed Journal Aging, utilizes Hyperbaric Oxygen Therapy protocols to demonstrate cellular level improvement in healthy aging adults.
For the first-time a human study shows the reversal in the biology of aging including telomere shortening with Hyperbaric Oxygen Therapy.
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Nov 18, 2020
Human ageing process biologically reversed in world first
Posted by Sean Brazell in categories: biotech/medical, life extension
Fantastic news for a change!
The ageing process has been biologically reversed for the first time by giving humans oxygen therapy in a pressurised chamber.
Scientists in Israel showed they could turn back the clock in two key areas of the body believed to be responsible for the frailty and ill-health that comes with growing older.
Continue reading “Human ageing process biologically reversed in world first” »
Nov 16, 2020
Chronic inflammation causes a reduction in NAD+
Posted by Kevin Huang in categories: biotech/medical, life extension
NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous age-related diseases and has spawned the development of many nutritional supplements aimed at restoring NAD+ to more youthful levels. Publishing in Nature Metabolism, researchers at the Buck Institute have identified chronic inflammation as a driver of NAD+ decline. They show that an increasing burden of senescent cells, which is also implicated in the aging process, causes the degradation of NAD via the activation of CD38 (cyclic ADP ribose hydrolase) a protein that is found on the cell membranes both inside and on the surface of many immune cells.
“We are very excited to link two phenomena which have been separately associated with aging and age-related disease,” said Eric Verdin, MD, Buck Institute President and CEO and senior author of the paper. “The fact that NAD+ decline and chronic inflammation are intertwined provides a more holistic, systemic approach to aging and the discovery of CD38 macrophages as the mediator of the link between the two gives us a new target for therapeutic interventions.”
