Lifeboat Foundation

Researchers at The University of Texas MD Anderson Cancer Center have shown that therapeutically restoring ‘youthful’ levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models. If these findings are validated in clinical trials, they could have important therapeutic implications for age-related diseases such as Alzheimer’s, Parkinson’s, heart disease, and cancer.

The study, published in Cell, identified a small molecule compound that restores physiological levels of telomerase reverse transcriptase (TERT), which normally is repressed with the onset of aging. Maintenance of TERT levels in aged lab models reduced cellular senescence and tissue inflammation, spurred new neuron formation with improved memory, and enhanced neuromuscular function, which increased strength and coordination.

The researchers show that TERT functions not only to extend telomeres, but also acts as a transcription factor to affect the expression of many genes directing neurogenesis, learning and memory, cellular senescence, and inflammation.

As he releases a book on extending life, leading researcher Sam Parnia explains why resurrection is no longer science-fiction.

Will artificial intelligence save us or kill us all? In Japan, AI-driven technology promises better lives for an aging population. But researchers in Silicon Valley are warning of untamable forces being unleashed– and even human extinction.

Will artificial intelligence make life better for humans or lead to our downfall? As developers race toward implementing AI in every aspect of our lives, it is already showing promise in areas like medicine. But what if it is used for nefarious purposes?

Continue reading “Will artificial intelligence save us or kill us? | Us & Them | DW Documentary” »

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Shan C, Gong YL, Zhuang QQ, Hou YF, Wang SM, Zhu Q, et al. Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson’s disease. Prog Neuro Psychopharmacol Biol Psychiatry 2019, 94: 109670.

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In the more than six million years since people and chimpanzees split from their common ancestor, human brains have rapidly amassed tissue that helps decision-making and self-control.

The large prefrontal cortex provides evolutionary and cognitive advantages over non-human primates — but there’s a cost.

Did you know letting crushed garlic sit for 10+ minutes before cooking it helps preserve more of its healthy polyphenols from heat? I learned a bunch of similar tidbits while researching this article on the best longevity foods!

Want to know the best longevity foods that increase lifespan to add to your diet? We pored through hundreds of studies and made a list!

A new material developed by Tohoku University records and stores stress history in structures through a luminescent effect, offering an innovative solution to monitor aging infrastructure without needing power or complex equipment.

Identifying deteriorating infrastructure can be as challenging as fixing it. However, researchers at Tohoku University have made this process easier with the development of an innovative new material.

The material responds to mechanical stimuli by recording stress history through a luminescent effect called an afterglow. This information is stored for a long time, and by applying the material to the surfaces of structures, researchers can observe changes in the afterglow to determine the amount of stress the material has experienced.

This new technology will give doctors a closer look. Introducing Pillbot: a tiny disposable robot that you swallow to let doctors see inside your body. In a live demo on the TED Talk stage, creators Alex Luekbe and Vivek Kumbhari show how this pill-sized device navigates the inside of your stomach with a camera, giving a direct view of the entire organ — without the discomfort of invasive procedures — paving the way for further exploration of the human body. “Inside each and every one of us holds mysteries and wonders that if unlocked, lead to better health, performance and longevity,” says Luebke. Visit the link in bio to watch the full talk.’