Lifeboat Foundation

A pair of new spacecraft that will observe our planet’s ever-changing water cycle, ice sheets and crust is in final preparations for a California launch no earlier than Saturday, May 19. The Gravity Recovery and Climate Experiment Follow-On (GRACE-FO) mission, a partnership between NASA and the German Research Centre for Geosciences (GFZ), will take over where the first GRACE mission left off when it completed its 15-year mission in 2017.

GRACE-FO will continue monitoring monthly changes in the distribution of mass within and among Earth’s atmosphere, oceans, land and ice sheets, as well as within the solid Earth itself. These data will provide unique insights into Earth’s changing climate, Earth system processes and even the impacts of some human activities, and will have far-reaching benefits to society, such as improving water resource management.

“Water is critical to every aspect of life on Earth—for health, for agriculture, for maintaining our way of living,” said Michael Watkins, GRACE-FO science lead and director of NASA’s Jet Propulsion Laboratory in Pasadena, California. “You can’t manage it well until you can measure it. GRACE-FO provides a unique way to measure water in many of its phases, allowing us to manage water resources more effectively.”

Not surprising and yet fascinating to actually see — “The researchers found that music activates the brain, causing whole regions to communicate. By listening to the personal soundtrack, the visual network, the salience network, the executive network and the cerebellar and corticocerebellar network pairs all showed significantly higher functional connectivity.”

“Ever get chills lis­ten­ing to a par­tic­u­lar­ly mov­ing piece of music? You can thank the salience net­work of the brain for that emo­tion­al joint. Sur­pris­ing­ly, this region also remains an island of remem­brance that is spared from the rav­ages of Alzheimer’s dis­ease. Researchers at the Uni­ver­si­ty of Utah Health are look­ing to this region of the brain to devel­op music-based treat­ments to help alle­vi­ate anx­i­ety in patients with demen­tia. Their research will appear in the April online issue of The Jour­nal of Pre­ven­tion of Alzheimer’s Disease…

https://www.uqpower.com.au/podcast/spotlight-on-ira-pastor-genetic-regeneration

Whole genome sequencing is more precise than other methods, and it just keeps getting faster and cheaper. Joel Sevinsky, head of the Molecular Science Laboratory at the Colorado Department of Public Health and Environment (CDPHE), told the Associated Press his lab can sequence the genome of a suspected pathogen in less than 72 hours.

Whole genome sequencing is already helping researchers address food-borne outbreaks, including a 2017 salmonella outbreak that stretched across 21 states, and the current romaine outbreak.

Continue reading “You Know That Romaine-Linked Outbreak? DNA Tech Is Fixing It” »

This month I’m participating in Cato Institute’s Cato Unbound discussion. Cato is one of the world’s leading think tanks. Here’s my new and second essay for the project:

Professor David D. Friedman sweeps aside my belief that religion may well dictate the development of AI and other radical transhumanist tech in the future. However, at the core of a broad swath of American society lies a fearful luddite tradition. Americans—including the U.S. Congress, where every member is religious—often base their life philosophies and work ethics on their faiths. Furthermore, a recent Pew study showed 7 in 10 Americans were worried about technology in people’s bodies and brains, even if it offered health benefits.

It rarely matters what point in American history innovation has come out. Anesthesia, vaccines, stem cells, and other breakthroughs have historically all battled to survive under pressure from conservatives and Christians. I believe that if formal religion had not impeded our natural secular progress as a nation over the last 250 years, we would have been much further along in terms of human evolution. Instead of discussing and arguing about our coming transhumanist future, we’d be living in it.

Continue reading “Deniers and Critics of AI Will Only Be Left Behind” »

A new biotech company co-founded by CRISPR pioneer Jennifer Doudna is developing a device that uses CRISPR to detect all kinds of diseases like malaria, tuberculosis, and Zika. The tech is still just in prototype phase, but research in the field is showing promising results. These CRISPR-based diagnostic tools have the potential to revolutionize how we test for diseases in the hospital, or even at home.

Called Mammoth Biosciences, the company is working on a credit card-sized paper test and smartphone app combo for disease detection. But the applications extend beyond that: The same technology could be used in agriculture, to determine what’s making animals sick or what sorts of microbes are found in soil, or even in the oil and gas industry, to detect corrosive microbes in pipelines, says Trevor Martin, the CEO of Mammoth Biosciences, who holds a PhD in biology from Stanford University. The company is focusing on human health applications first, however.

Continue reading “This company is making an at-home CRISPR kit to find out what’s making you sick” »

Health service chief calls for affordable access to CAR-T, which modifies immune system to destroy cancer cells.

Sarah Boseley Health editor.

Thu 26 Apr 2018 13.29 EDT Last modified on Thu 26 Apr 2018 17.00 EDT.

Continue reading “NHS preparing to offer ‘game-changing’ cancer treatment” »

Wilmington, DE, April 19, 2018 — Scientists at Christiana Care Health System’s Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.

Investigators at the Gene Editing Institute, which is part of the Helen F. Graham Cancer Center & Research Institute at Christiana Care, said their new “cell-free” CRISPR technology is the first CRISPR tool capable of making multiple edits to DNA samples “in vitro,” which means in a test tube or petri dish. The advance could have immediate value as a diagnostic tool, replicating the exact genetic mutations found in the tumors of individual cancer patients. Mutations that cause cancer to spread can differ from patient to patient, and being able to quickly identify the correct mutation affecting an individual patient can allow clinicians to implement a more targeted treatment strategy.

“With this new advance, we should be able to work with laboratory cultures and accomplish gene edits in less than a day, significantly reducing the time required for diagnostics compared to other CRISPR tools, and with much greater precision,” said Eric Kmiec, Ph.D., director of the Gene Editing Institute and principal author of the study. “This is particularly important for diagnostics linked to cancer care where time is critical.”

A UK man who caught what was dubbed the world’s “worst-ever” case of super-gonorrhoea has been cured, Public Health England (PHE) said — but two similar cases have been reported in Australia.

The unidentified heterosexual man, who had a partner in the UK, picked up the infection having sex with another woman in South-East Asia, PHE said.

Health officials said it was the first time the infection could not be cured with the regular treatment — a combination of antibiotics azithromycin and ceftriaxone.

Continue reading “UK man’s super-gonorrhoea cured — but now two Australians have it” »