Lifeboat Foundation

Japanese Researchers Create Immature Human Eggs From Stem Cells : Shots — Health News A Japanese research team made immature human eggs from stem cells that were derived from human blood. The technique brings scientists a step closer to being able to mass-produce human eggs.

All three of these surprising achievements are highlighted in the Goalkeepers 2018 Data Report, written by Bill and Melinda Gates and released on Sept. 18. But the dispatch—an assessment of the progress made so far on the United Nations’ 17 Sustainable Development Goals and done with the help of the University of Washington’s Institute for Health Metrics and Evaluation—is anything but rah-rah. For every encouraging data point, indeed, there is one that alarms. For every promising advance in the global war on poverty and disease is a perilous outcome if we lose focus or steam.

A report from the Bill & Melinda Gates Foundation focuses on four key areas: Health, education, sanitation, and family planning.

Recently, there has been an explosion of interest in applying artificial intelligence (AI) to medicine. Whether explicitly or implicitly, much of this interest has centered on using AI to automate decision-making tasks that are currently done by physicians. This includes two seminal papers in the Journal of the American Medical Association demonstrating that AI-based algorithms have similar or higher accuracy than physicians: one in diagnostic assessment of metastatic breast cancer compared to pathologists and the other in detecting diabetic retinopathy compared to ophthalmologists.

While promising, these applications of AI in medicine raise a number of novel regulatory and policy issues around efficacy, safety, health workforce, and payment. They have also triggered concerns from the medical and patient communities about AI replacing doctors. And, except in narrow domains of practice, general AI systems may fall far short of the hype.

We posit that the applications of AI to “augment” physicians may be more realistic and broader reaching than those that portend to replace existing health care services. In particular, with the right support from policy makers, physicians, patients, and the technology community, we see opportunities for AI to be a solution for—rather than a contributor to—burnout among physicians and achieving the quadruple aim of improving health, enhancing the experience of care, reducing cost, and attaining joy in work for health professionals.

Chinese vice-premier Liu He called on the world to work together to address complex ethical, legal and other questions raised by artificial intelligence as he kicked off a gathering in Shanghai bringing together the globe’s AI elites.

“As members of a global village, I hope countries can show inclusive understanding and respect to each other, deal with the double-sword technologies can bring, and together embrace AI,” said Liu, a highly influential official who has been China’s top trade negotiator in the US-China trade war and is also on the country’s technology development committee.

The star-studded World Artificial Intelligence Conference, which opened Monday morning, comes as China has emerged as one of the world’s top players in AI, which promises to revolutionise everything from health care to driving to policing.

Continue reading “Chinese vice-premier calls on global AI elites to tackle ethics questions” »

(HealthDay)—The ancient practice of tai chi may beat strength training and aerobics for preventing falls among seniors, a new trial shows.

A modified senior-centered tai chi program reduced falls nearly a third better in a head-to-head comparison with an exercise regimen that combined aerobics, strength training and balance drills, the researchers reported.

“This tai chi program better addressed the deficits that were contributing to fall risk,” said senior researcher Kerri Winters-Stone, a professor with the Oregon Health & Science University School of Nursing.

In the vicissitudes of life, our recent and living generations moved from the hard times of a hundred years ago to the exponential good times of today. Now a few hundred key pioneers have positioned the world in front of the opportunities of Transhumanism and its main tenet, indefinite life extension. Will we unite the world on these issues and capitalize or waste it and let the weeds reclaim our “wheel”, the magnum opus of our generations? I challenge all would-be leaders and followers to honor our ancestors’ long tradition of pioneering the next stages of our future. Everything about you was crafted and honed for this and there is no other time. Find the blazers of our emerging values and paths, your philosophers of the future, out there at the forefronts on this epic new transhuman voyage of freedoms and discoveries and follow them. All leaders who haven’t already, I implore you to fully embrace your roles, triple down and raise your flags even higher. Friedrich Nietzsche wrote a book preluding this philosophy of the future, which serves as the structure for this paper and is quoted here throughout.

“[Conditioning to hard times] is thus established, unaffected by the vicissitudes of generations; the constant struggle with uniform unfavourable conditions is, as already remarked, the cause of a type becoming stable and hard. Finally, however, a happy state of things results, the enormous tension is relaxed; there are perhaps no more enemies among the neighbouring peoples, and the means of life, even of the enjoyment of life, are present in superabundance. With one stroke the bond and constraint of the old discipline severs: it is no longer regarded as necessary, as a condition of existence—if it would continue, it can only do so as a form of luxury, as an archaizing taste. Variations, whether they be deviations (into the higher, finer, and rarer), or deteriorations and monstrosities, appear suddenly on the scene in the greatest exuberance and splendour; the individual dares to be individual and detach himself. At this turning-point of history there manifest themselves, side by side, and often mixed and entangled together, a magnificent, manifold, virgin-forest-like up-growth and up-striving, a kind of tropical tempo in the rivalry of growth, and an extraordinary decay and self-destruction, owing to the savagely opposing and seemingly exploding aptitudes, which strive with one another ‘for sun and light,’ and can no longer assign any limit, restraint, or forbearance for themselves by means of the hitherto existing morality. It was this morality itself which piled up the strength so enormously, which bent the bow in so threatening a manner:—it is now ‘out of date,’ it is getting ‘out of date.’ ” – Friedrich Nietzsche, Beyond Good and Evil: Prelude to a Philosophy of the Future

Our elders came from the great depression and world war. Then they had to watch what they called “morals”, but which were actually just coping mechanisms particular to their vicissitude of time, as Nietzsche gets at in various places, become increasingly disregarded. That happened faster than ever because, little did they know, the bell curve of exponential advancements in fields across the board were upon them. The variations of excellence and monstrosities proliferated like no other time and were supercharged for an abundant harvest by the buds of enlightenment and technology that had been poking their heads out of the fertile intellectual fields of civilization from the smatterings of good times they were able to come upon throughout the century. A lot of it was stored as compounding action potential. It went off like rifles in the 50s and 60s, with so much force that the bullets are still flying today, and the shots of individual aptitude have been firing ever since. Like he is saying, it’s a jungle of individual morals competing in the survival of the fittest, so you must find ways, that hard times naturally make, to get all these independent construction workers of the best ideas behind the same projects in order to tap that energy for the big stages and human potentials.

This is our window in time here, as I often say, to get projects like life extension, transhumanism, space exploration, and some other things done. The people of the past didn’t have this opportunity and the chance here isn’t available forever because death will close us off from it or bad times will set back in. A great gate in Plato’s cave has opened, the eternal guard lions of death have left their posts and we don’t know how long until they come back or the gate closes. It is devastating watching those who have been hypnotized by the cave, by the death trance, sitting there with a wide-open door and the clock ticking down. The climb must be made, now is the time, there is no other. Team up and follow the leaders on these new emerging circumstances and moral imperatives or everyone will die as the marvels of space and boundless technology tumble from our hands. We rouse them to action slowly but surely, though all as one, more gets done.

Continue reading “Notes from Nietzsche and some Correlations with Transhumanism” »

Your body’s internal clock, or the circadian rhythm, regular when you sleep and wake, when you’re hungry, and when you’re most productive. Because of its effect on so much of our lives, it also has an enormous impact on our health, so sleep experts have designed a blood test to signal when your body is out of sync.

MIT professor Dina Katabi is building a gadget that can sit in one spot and track everything from breathing to walking, no wearables required.

A new study on adult neurogenesis and Alzheimer’s disease.

According to a study led by scientists at Massachusetts General Hospital, exercise-induced neurogenesis improves cognition in a mouse model of Alzheimer’s disease, yielding more benefits than drug-induced adult neurogenesis. The scientists were able to figure out the difference between the two types of induced neurogenesis and pharmacologically reproduce the same benefits provided by exercise [1].

Study abstract

Continue reading “Exercise Induces Adult Neurogenesis and Ameliorates Alzheimer’s Disease in Mice” »