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For Rance and others in the field, fezolinetant’s progress to this point is a sign that research into the causes and effects of menopausal symptoms is finally being taken seriously. In the next few years, the global number of postmenopausal women is expected to surpass one billion. But many women still struggle to access care related to menopause, and research into how best to manage such symptoms has lagged behind. That is slowly changing. Armed with improved animal models and a growing literature on the effects of existing treatments, more researchers are coming into the field to fill that gap.

They increasingly recognize that menopause and the transition to it, a phase labelled perimenopause, could set the stage for brain health in later life, and there are even hints that it could correlate with the risk of neurodegenerative diseases, such as Alzheimer’s disease.

Fezolinetant and similar drugs in the pipeline also represent a shift in thinking: from menopause as a condition of the female reproductive organs, to one that focuses on neurological causes and effects. “We think of menopause as being driven by changes in the ovary,” says Hadine Joffe, who studies mental health and ageing in women at Harvard Medical School in Boston, Massachusetts. “The notion of the brain at the helm of menopause, that is a different concept.”

Virgin hair refers to hair that grows back after chemotherapy and may differ in color, curliness, or texture. Learn how to care for your new style.

A new algorithm developed by Chinese company Baidu Research is dramatically faster than prior methods and shown to boost the antibody response of mRNA vaccines by up to 128 times.

Baidu Research is the research arm of Baidu, one of the largest technology companies in China. Established in 2014, it has since then been involved in various research activities such as natural language processing (NLP), machine learning, computer vision, robotics, and other areas of artificial intelligence.

Language and speech are how we express our inner thoughts. But neuroscientists just bypassed the need for audible speech, at least in the lab. Instead, they directly tapped into the biological machine that generates language and ideas: the brain.

Using brain scans and a hefty dose of machine learning, a team from the University of Texas at Austin developed a “language decoder” that captures the gist of what a person hears based on their brain activation patterns alone. Far from a one-trick pony, the decoder can also translate imagined speech, and even generate descriptive subtitles for silent movies using neural activity.

Here’s the kicker: the method doesn’t require surgery. Rather than relying on implanted electrodes, which listen in on electrical bursts directly from neurons, the neurotechnology uses functional magnetic resonance imaging (fMRI), a completely non-invasive procedure, to generate brain maps that correspond to language.

Glioblastoma is one of the most common and aggressive forms of brain cancer, and it’s one of the hardest to treat. There may be good news on the horizon, however.

A newly developed hydrogel, tested on mice, cleaned up traces of glioblastoma tumors and stopped them from returning. The hydrogel was so effective that there was a “striking” 100 percent survival rate in the animals.

Continue reading “A Newly Developed Hydrogel Can Wipe Out Brain Cancer in Mice” »

HOUSTON (AP) — Fire erupted at a petrochemical plant in the Houston area Friday, sending nine workers to a hospital and causing a huge plume of smoke visible for miles.

Emergency responders were called to help around 3 p.m. at the Shell facility in Deer Park, a suburb east of Houston. The city of Deer Park said in an advisory that there was no shelter-in-place order for residents.

Harris County Sheriff Ed Gonzalez said earlier in the day that five contracted employees were hospitalized for precautionary reasons, adding that they were not burned. He said they were taken to a hospital due to heat exhaustion and proximity to the fire.

A new study published in Human Brain Mapping revealed that long-term musical training can modify the connectivity networks in the brain’s white matter.

Previous research has shown that intense musical training induces structural neuroplasticity in different brain regions. However, previous studies mainly investigated brain changes in instrumental musicians, and little is known about how structural connectivity in non-instrumental musicians is affected by long-term training.

To examine how the connections between different parts of the brain might be affected by long-term vocal training, the researchers of the study used graph theory and diffusion-weighted images. Graph theory is a mathematical framework used to study the networks’ architecture in the human brain, while diffusion-weighted imaging is an MRI technique that measures the diffusion of water molecules in tissues, providing information on the structural connectivity of the brain.

A fever is the immune system’s response to an infection or invader. Most fevers drop after people take over-the-counter medications. People should call a doctor if their fever reaches 103° F and go to an emergency room if it reaches 105°.

It’s a dangerous world out there. From bacteria and viruses to accidents and injuries, threats surround us all the time. And nothing protects us more steadfastly than our skin. The barrier between inside and out, the body’s largest organ is also its most seamless defense.

And yet the skin is not invincible. It suffers daily the slings and arrows of outrageous fortune, and it tries to keep us safe by sensing and responding to these harms. A primary method is the detection of a pathogen, which kicks the immune system into action. But new research from the lab of Rockefeller’s Elaine Fuchs, published in Cell, reveals an alternative protective mechanism that responds to injury signals in wounded tissue—including low oxygen levels from blood vessel disruption and scab formation—and it doesn’t need an infection to get into gear.

The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.