Lifeboat Foundation

Once again the figures show that young to old disparity in the population is the problem not overpopulation. We really need to develop rejvenation biotechnology with all haste.

Once again overpopulation isnt the problem it is the disparity between young and old in the workforce. This makes rejuvenation biotechnology a suitable solution to avoid economic collapse.

“The world is experiencing unparalleled population aging. This poses problems for productivity and growth, unless we do something about it”

Continue reading “An Aging Population Is Stalling Productivity” »

Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and First Affiliated Hospital of Zhengzhou University have developed a synthetic version of a cardiac stem cell. These synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem cell therapies. Additionally, these cells have better preservation stability and the technology is generalizable to other types of stem cells.

Stem cell therapies work by promoting endogenous repair; that is, they aid damaged tissue in repairing itself by secreting “paracrine factors,” including proteins and genetic materials. While stem cell therapies can be effective, they are also associated with some risks of both tumor growth and immune rejection. Also, the cells themselves are very fragile, requiring careful storage and a multi-step process of typing and characterization before they can be used.

Ke Cheng, associate professor of molecular biomedical sciences at NC State, associate professor in the joint biomedical engineering program at NC State and UNC, and adjunct associate professor at the UNC Eshelman School of Pharmacy, led a team in developing the synthetic version of a cardiac stem cell that could be used in off-the-shelf applications.

The immune system part 1.

Our final episodes of Anatomy & Physiology explore the way your body keeps all that complex, intricate stuff alive and healthy — your immune system. The immune system’s responses begin with physical barriers like skin and mucous membranes, and when they’re not enough, there are phagocytes — the neutrophils and macrophages. It also features the awesomely named natural killer cells and the inflammatory response, and we’ll explain how all of these elements work together to save the day if you happen to slip on a banana peel.

Continue reading “Immune System, part 1: Crash Course A&P #45” »

The genetically engineered _Drosophila melanogaster _can even signal for different types of breast cancer cells.

University of Konstanz.

Continue reading “After Genetic Tweaks, Fruit Flies Glow When They Sense Cancer” »

Scientist Carl Sagan said many times that “we are star stuff,” from the nitrogen in our DNA, the calcium in our teeth, and the iron in our blood.

It is well known that most of the essential elements of life are truly made in the stars. Called the “CHNOPS elements” – carbon, hydrogen, nitrogen, oxygen, phosphorous, and sulfur – these are the building blocks of all life on Earth. Astronomers have now measured of all of the CHNOPS elements in 150,000 stars across the Milky Way, the first time such a large number of stars have been analyzed for these elements.

“For the first time, we can now study the distribution of elements across our Galaxy,” says Sten Hasselquist of New Mexico State University. “The elements we measure include the atoms that make up 97% of the mass of the human body.”

Experts warn that a potential IVF breakthrough could have unintended social consequences.

A while ago I got an idea: how awesome would it be to use 4D ultrasound to scan my unborn baby and make a VR experience of that. So I talked my girlfriend over even though the idea felt a bit weird and almost scary.

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How to make it happen? I searched for similar cases online, but couldn’t find any. All I could find was some examples of using ultrasound images for a 3D print of your unborn baby. So this was the first time in the world someone was doing this. Luckily I got people at the Aava Medical Centre excited about the idea, and they helped me forward. I also contacted GE, a manufacturer of 4D ultrasound systems, and they advised me how to extract the right kind of files from the ultrasound machine.

When Brian Hanley set out to test a gene therapy, he started with himself.

The microglia are central to aging in the brain and science is already finding ways to reverse it like introducing young microglia to the brain to remove plaques associated with Alzheimers. Brain aging is not a one way process!

The difference between an old brain and a young brain isn’t so much the number of neurons but the presence and function of supporting cells called glia. In Cell Reports on January 10, researchers who examined postmortem brain samples from 480 individuals ranging in age from 16 to 106 found that the state of someone’s glia is so consistent through the years that it can be used to predict someone’s age. The work lays the foundation to better understand glia’s role in late-in-life brain disease.

“We extensively characterized aging-altered gene expression changes across 10 human brain regions and found that, in fact, glial cells experience bigger changes than neurons,” says Jernej Ule, a neurobiologist at the Francis Crick Institute and the University College London, who led the study with departmental colleague Rickie Patani (@PataniLab) and first author Lilach Soreq. “There’s quite a bit of regional information that will be of interest to different people—for example some will notice a very unique pattern of astrocyte-specific changes in the substantia nigra—and we provide a lot of data that still needs to be analyzed.”

Continue reading “Glia, not neurons, are most affected by brain aging” »