Lifeboat Foundation

Finally, maybe hope for GBM patients.

In a rapid-fire series of breakthroughs in just under a year, researchers at the University of North Carolina at Chapel Hill have made another stunning advance in the development of an effective treatment for glioblastoma, a common and aggressive brain cancer. The work, published in the Feb. 1 issue of Science Translational Medicine, describes how human stem cells, made from human skin cells, can hunt down and kill human brain cancer, a critical and monumental step toward clinical trials — and real treatment.

Last year, the UNC-Chapel Hill team, led by Shawn Hingtgen, an assistant professor in the Eshelman School of Pharmacy and member of the Lineberger Comprehensive Care Center, used the technology to convert mouse skin cells to stem cells that could home in on and kill human brain cancer, increasing time of survival 160 to 220 percent, depending on the tumor type. Now, they not only show that the technique works with human cells but also works quickly enough to help patients, whose median survival is less than 18 months and chance of surviving beyond two years is 30 percent.

Continue reading “Revolutionary approach for treating glioblastoma works with human cells” »

Scientists at The Scripps Research Institute (TSRI) have found that deep brain stimulation (DBS) can greatly reduce the compulsion to use heroin in standard rat models of addiction.

Rats that were used to taking heroin, and normally would have self-administered more and more of the drug, did not escalate their intake when treated with DBS.

The treatment involves the weak electrical stimulation, via implanted electrodes, of a brain region called the subthalamic nucleus.

Continue reading “Scientists show deep brain stimulation blocks heroin relapse in rats” »

https://youtube.com/watch?v=eEHVS0URsWE

Great method btw.

Epilepsy is the fourth most common neurological disorder in the United States. Patients who have it are of all ages and it can seriously limit one’s ability to enjoy life. It’s a spectrum disorder which means the kinds of seizures people suffer and how they are managed will vary depending on the patient. Currently about 3 million people in the US are living with epilepsy and experts predict that at least 1 in 26 people will develop epilepsy at some point in their lifetime. While epilepsy is most often treated with anti-seizure medication, there are some patients who have not benefitted from medication. This form of the disorder is called drug-resistant epilepsy and can be very difficult to treat.

Continue reading “Mapping the Brain Before Surgery for Epilepsy” »

Certainly explains patterns in certain families.

TUESDAY, Jan. 31, 2017 (HealthDay News) — Developing or worsening type 2 diabetes could be an early sign of pancreatic cancer, new research suggests.

Researchers analyzed data from nearly a million patients with type 2 diabetes or pancreatic cancer in Italy and Belgium. Half of all pancreatic cancer cases were diagnosed within a year of patients being diagnosed with diabetes, the findings showed.

Continue reading “Is There a Link Between Diabetes and Pancreatic Cancer?” »

Nice.

When you think of diamonds, rings and anniversaries generally come to mind. But one day, the first thing that will come to mind may be bone surgery. By carefully designing modified diamonds at the nano-scale level, a Missouri University of Science and Technology researcher hopes to create multifunctional diamond-based materials for applications ranging from advanced composites to drug delivery platforms and biomedical imaging agents.

Dr. Vadym Mochalin, an associate professor of chemistry and materials science and engineering at Missouri S&T, is characterizing and modifying 5-nanometer nanodiamond particles produced from expired military grade explosives so that they can be developed to perform specific tasks. His current research studies their use as a filler in various types of composites.

Continue reading “Missouri S&T researcher works to develop nanodiamond materials” »

Highly sophisticated robotics and ‘bio-printing’ are rapidly changing the face of modern surgery, significantly eliminating the risk of human error and in some cases even allowing doctors to perform procedures remotely, according to experts at Arab Health.

Dr Peter C.W. Kim, vice-president and associate surgeon-in-chief of the Joseph E. Roberts Jr. Centre for Surgical Care at Washington DC’s Children’s National — which has received millions of dollars in donations from the UAE’s government — noted that doctors will soon be able to 3D-print using bio-tissue, such as for an eardrum.

“What our engineers and researchers have done is not only design the plastic with it, but also graft cells onto it,” he said. “This is where we are going. You will (in the future) be able to have organs on the shelf. Instead of harvesting it, you can print it.”

Continue reading “Robots and bio-printing change the face of surgery in UAE” »

San Francisco-based research company Otherlab is developing a new concept for disposable delivery drones made of cardboard.

The project is funded by the US Defense Advanced Research Agency (DARPA), and it aims to develop drones which can be used to deliver medical supplies and other cargo to remote or hard-to-reach locations.

The drone is designed to make only an outward journey – no returns – and then be discarded. The fact that the drone only has to make a one-way trip will extend its range. The vehicle’s primary method of propulsion will be gliding.

The Parker Institute for Cancer Immunotherapy has partnered with dozens of organizations to develop a cancer vaccine to prevent the disease which is expected to grow by an additional 21.7 million through 2030. The plan is to target genetic markers specific to tumors to allow the body to generate an immune response to combat the cancer before it ever takes hold.

An international team of scientists has developed a soft robotic sleeve that can be implanted on the external surface of the heart to restore blood circulation in pigs (and possibly humans in the future) whose hearts have stopped beating.

The device is a silicone-based system with two layers of actuators: one that squeezes circumferentially and one that squeezes diagonally, both designed to mimic the movement of healthy hearts when they beat.

Continue reading “Soft robotic sleeve developed to aid failing hearts” »