Lifeboat Foundation

The paranasal sinuses are major producers of nitric oxide (NO). We hypothesized that oscillating airflow produced by humming would enhance sinus ventilation and thereby increase nasal NO levels. Ten healthy subjects took part in the study. Nasal NO was measured with a chemiluminescence technique during humming and quiet single-breath exhalations at a fixed flow rate. NO increased 15-fold during humming compared with quiet exhalation. In a two-compartment model of the nose and sinus, oscillating airflow caused a dramatic increase in gas exchange between the cavities. Obstruction of the sinus ostium is a central event in the pathogenesis of sinusitis. Nasal NO measurements during humming may be a useful noninvasive test of sinus NO production and ostial patency. In addition, any therapeutic effects of the improved sinus ventilation caused by humming should be investigated.

The company’s update on its development of COVID-19 drug candidate is promising.

Vancouver, British Columbia—(Newsfile Corp. — March 31, 2020) — NanoViricides, Inc. (NYSE American: NNVC) (the “Company”) is a nano-biopharmaceutical Company at the development stage, with proprietary and patented drug development work focused on viral diseases. The Company’s research involves the use of a unique nanomedicine technology called nanoviricides — agents designed to “fool” a virus into attaching to an antiviral nanomachine, in the same way that the virus normally attaches to the receptors on a cell surface, but for the purpose of its neutralization and destruction. NanoViricides was highlighted by SmallCapsDaily for providing an update on its progress to develop a drug that can treat COVID-19, the coronaviral pneumonia disease which is caused by the SARS-CoV-2 virus, aka, 2019-nCoV, also known as the Wuhan coronavirus.

Step two of…

(Meanwhile in Bangladesh)

The ID2020 Alliance has launched a new digital identity program at its annual summit in New York, in collaboration with the Government of Bangladesh, vaccine alliance Gavi, and new partners in government, academia, and humanitarian relief.

Continue reading “ID2020 and partners launch program to provide digital ID with vaccines” »

Shane chats with former NSA spy and whistleblower Edward Snowden on the rise of authoritarianism during the COVID-19 pandemic.

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Apple Inc. and Google unveiled a rare partnership to add technology to their smartphone platforms that will alert users if they have come into contact with a person with Covid-19. People must opt in to the system, but it has the potential to monitor about a third of the world’s population.

The role of automatic electrocardiogram (ECG) analysis in clinical practice is limited by the accuracy of existing models. Deep Neural Networks (DNNs) are models composed of stacked transformations that learn tasks by examples. This technology has recently achieved striking success in a variety of task and there are great expectations on how it might improve clinical practice. Here we present a DNN model trained in a dataset with more than 2 million labeled exams analyzed by the Telehealth Network of Minas Gerais and collected under the scope of the CODE (Clinical Outcomes in Digital Electrocardiology) study. The DNN outperform cardiology resident medical doctors in recognizing 6 types of abnormalities in 12-lead ECG recordings, with F1 scores above 80% and specificity over 99%. These results indicate ECG analysis based on DNNs, previously studied in a single-lead setup, generalizes well to 12-lead exams, taking the technology closer to the standard clinical practice.

Amid the coronavirus pandemic that has spread across the U.S., a number of states have extended their lockdown orders in an effort to combat the spread of the virus.

As of April 8, every U.S. state has reported confirmed coronavirus cases but the stay-at-home and shelter-in-place policies all came at different times. California was the first state to issue a stay-at-home order on March 19, while South Carolina was the most recent, issuing their statewide order on April 7. Some other states like Arkansas, Iowa, North Dakota and Nebraska have yet to issue statewide stay-at-home orders.

The new viruses are not harmful to humans or closely related to SARS-CoV-2, the coronavirus that causes COVID-19.