Lifeboat Foundation

Dwight E. Bergles, Ph.D., a leading neuroscientist at Johns Hopkins University School of Medicine, is the winner of the prestigious Barancik Prize for Innovation in MS Research. Bergles has pioneered the study of immature cells in the brain that can regenerate myelin-making cells after myelin is destroyed in MS. These cells, oligodendrocyte precursor cells (OPCs), hold the key to finding ways to promote myelin repair and restore function for people living with multiple sclerosis.

Understanding heat dissipation processes at nanoscale during cellular thermogenesis is essential to clarify the relationships between the heat and biological processes in cells and organisms. A key parameter determining the heat flux inside a cell is the local thermal conductivity, a factor poorly investigated both experimentally and theoretically. Here, using a nanoheater/nanothermometer hybrid made of a polydopamine encapsulating a fluorescent nanodiamond, we measured the intracellular thermal conductivities of HeLa and MCF-7 cells with a spatial resolution of about 200 nm. The mean values determined in these two cell lines are both 0.11 ± 0.04 W m−1 K−1, which is significantly smaller than that of water. Bayesian analysis of the data suggests there is a variation of the thermal conductivity within a cell.

Dr. Hassan A. Tetteh, MD, is the Health Mission Chief, at the Department of Defense (DoD) Joint Artificial Intelligence Center, serving to advance the objectives of the DoD AI Strategy, and improve war fighter healthcare and readiness with artificial intelligence implementations.

Dr. Tetteh is also an Associate Professor of Surgery at the Uniformed Services University of the Health Sciences, adjunct faculty at Howard University College of Medicine, a Thoracic Staff Surgeon for MedStar Health and Walter Reed National Military Medical Center, and leads a Specialized Thoracic Adapted Recovery (STAR) Team, in Washington, DC, where his research in thoracic transplantation aims to expand heart and lung recovery and save lives.

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Scientists recently captured a high-resolution video of DNA shimmying into weird shapes in order to squeeze inside cells.

Researchers from the German Kiel University have developed novel 3D printed ‘spiky-joints’ that provide wrist injury patients with a more flexible form of arm support.

Inspired by the natural wing micro-joints of the dragonfly, the spiky-joint features a novel interlocking mechanism that’s designed to cushion the wrist without impairing free movement. When set to its maximum rigidity, the scientists believe their device could be ideal for treating everyday strains and sprains, and preventing common hyperextension injuries in athletes.

Scientists have cloned the first U.S. endangered species, a black-footed ferret duplicated from the genes of an animal that died over 30 years ago.

HOW CUTE 🥰 Meet Elizabeth Ann, the first-ever cloned U.S. endangered species. She’s a black-footed ferret duplicated from the genes of an animal that died in 1988.

“You might have been handling a black-footed ferret kit and then they try to take your finger off the next day,” U.S. Fish and Wildlife Service black-footed ferret recovery coordinator Pete Gober said Thursday. “She’s holding her own.”

Elizabeth Ann was born and is being raised at a Fish and Wildlife Service black-footed ferret breeding facility in Fort Collins, Colorado. She’s a genetic copy of a ferret named Willa who died in 1988 and whose remains were frozen in the early days of DNA technology.

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As we assembled our second annual TIME100 Next list—an expansion of our flagship TIME100 franchise that highlights 100 emerging leaders who are shaping the future—what struck me most was how its members are coping with crisis.

Amid a global pandemic, deepening inequality, systemic injustice and existential questions about truth, democracy and the planet itself, the individuals on this year’s list provide “clear-eyed hope,” as actor, composer and director Lin-Manuel Miranda puts it in his tribute to poet and TIME100 Next honoree Amanda Gorman. They are doctors and scientists fighting COVID-19, advocates pushing for equality and justice, journalists standing up for truth, and artists sharing their visions of present and future.

Chronic increases of the cytokine IL-17a circulating in the blood of mice reduced microglia activity in one region of the hippocampus, an area of the brain critical for memory and learning.