Armed with gene technologies and CAR-Ts, scientists are attempting to eliminate viruses that escape immune detection and lurk in tissues for years.
Biotech stocks could be at a major turning point after FDA approval of the first gene editing drug using CRISPR technology to treat sickle cell disease. Gove…
A team of scientists used gene editing to create what they thought would be a calmer rodent. Instead, the gene-edited rodents were angrier.
A new Seattle biotech organization will be funded to the tune of $75 million to research “DNA typewriters,” self-monitoring cells that could upend our understanding of biology. The collaboration between the University of Washington, the Chan-Zuckerberg Initiative and the Allen Institute is already underway.
Called the Seattle Hub for Synthetic Biology, the joint initiative will combine the expertise of the two well-funded research outfits with that of UW Medicine, working in what UW’s Jay Shendure, scientific lead for the project, called “a new model of collaboration.”
The Hub (not to be confused with the HUB, or Husky Union Building, on UW’s campus) aims to strike a balance between a disinterested intellectual academic approach and a development-focused commercial approach. The $75 million will fund the organization for five years, with the option to renew then.
These three gene therapy stocks should get huge boosts over the long term from the use of gene editing techniques to treat diseases.
Good telescope that I’ve used to learn the basics: https://amzn.to/35r1jAk.
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Hello and welcome! My name is Anton I’m away for a few days due to voice issues, so enjoy this older video where we talk about the incredible invention of 3D printed bio ink that could be used to print any biological tissue (in theory). 3D printed heart anyone?
Continue reading “Bio Ink Made out of Bacteria Could Be Used to 3D Print Organs” »
Discover our selection of discounted synthetic biology tools, perfect for advancing biomedicine, cell-cultured meats, and sustainable textiles.
In our latest feature, we explore the future of gene editing and the challenges we must overcome to harness its full potential.
Target validation is a crucial step in pre-clinical drug discovery workflows that builds confidence on the identification of a genetic target as relevant to a disease. With recent advancements, CRISPR serves as a particularly powerful tool for this process, as it enables researchers to accurately modify genes and determine their function in a variety of experimental systems.
One scientist leveraging CRISPR gene editing in this way is Dr. Panos Zalmas, Head of the Open Targets Validation Lab based at the Wellcome Sanger Institute, whose work focuses on discovering and validating new putative disease targets for the development of safe and effective medicines.
In this SelectScience® interview, we speak with Zalmas to learn how he is working to improve the rate of target adoption into drug discovery pipelines across therapy areas such as oncology, neurodegeneration, and immunology and inflammation. Here, Zalmas explains the importance of gene editing in his target validation workflows and highlights how CRISPR technologies in particular are key to the success of drug discovery.
Researchers have been able to reduce dramatically the level of bad cholesterol in human subjects after injecting them with an experimental gene editing treatment, according to the science journal Nature, which is the first time this technique, called base editing, has been done on humans.
But at least one person died after receiving an infusion, prompting a round of safety concerns.
In the clinical trial, 10 subjects with congenitally high levels of bad cholesterol, aka low-density lipoprotein (LDL), were given an injection of VERVE-101, a gene-editing treatment that uses the base editing technique. This treatment then turned off the gene for the protein PCSK9, which is found in the liver and regulates LDL. High levels of LDL can lead to coronary heart disease.
