Lifeboat Foundation

260 posts by Mike Lustgarten

• Is C15 A Good Measure Of Aging? – October 20, 2024
• Red Light Therapy Improves Mitochondria Function, Eye Health, And Lifespan: Glen Jeffery, PhD – October 16, 2024
• It’s Time To Science The Sh** Out Of DunedinPACE – October 13, 2024
• The 900-Day Rule For Evaluating Longevity Interventions (Paper Presentation By Kamil Pabis, MSc) – October 9, 2024
• P-Cresyl And Indoxyl Sulfates Are Gut Bacteria-Derived Metabolites That May Be Bad For Longevity – October 6, 2024
• Whole Body Flexibility Is Associated With Reduced All-Cause Mortality Risk – October 2, 2024
• Siim Land’s Health, Fitness, And Longevity Approach – September 29, 2024
• 13y Younger Biological Age (Blood Test #6 in 2024; Test #54 Since 2015) – September 22, 2024
• Optimizing Plasma Taurine: 10-Test Analysis – September 15, 2024
• 6y Younger Horvath Epigenetic Age: My Best Data Yet (16-Test Analysis) – September 8, 2024
• 62-Year Old Dave Pascoe: Slowing Aging Inside And Out – September 1, 2024
• Telomere Length Test #16: My Best Data Yet – August 28, 2024
• Kynurenine/Tryptophan Is Associated With Biomarkers Of Neurodegenerative Disease – August 25, 2024
• High Mushroom Intake, High Homocysteine? – August 21, 2024
• Diet Composition That Corresponds To A 17.6y Younger Biological Age (Blood Test #5 In 2024) – August 18, 2024
• 17.6y Younger Biological Age: Supplements (Blood Test #5 In 2024) – August 16, 2024
• Is NAD Correlated With Telomere Length, Biological Age, Or Other Biomarkers? – August 11, 2024
• 17.6y Younger Biological Age (Blood Test #5 In 2024) – August 7, 2024
• Lead Is Associated With An Older Biological Age And An Increased Mortality Risk – August 4, 2024
• Which Biomarkers Are Most Predictive Of Biological Age? – July 31, 2024
• 41% Increase For HRV Since 2018 – July 24, 2024
• A High Calcium Diet Reduces Oxalate Absorption – July 21, 2024
• Telomere Length Test #15: Correlations With Diet – July 14, 2024
• Which Nutrients Are Associated With A Younger Brain Age? – July 10, 2024
• What’s Optimal For Grip Strength During Aging? – July 7, 2024
• Visceral Fat Removal Extends Lifespan – July 3, 2024
• Sulforaphane Extends Lifespan, Increases Muscle Strength And Endurance – June 30, 2024
• Plasma Trigonelline: A Mediator For Dietary Trigonelline To Increase NAD? (8-Test Analysis) – June 26, 2024
• 17.5y Younger Biological Age: Supplements, Diet (Blood Test #4 in 2024) – June 19, 2024
• Is Coffee Associated With A Younger Biological Age? – June 16, 2024
• Resisting An Increased Epigenetic Speed Of Aging (14-Test Results) – June 9, 2024
• Horvath Epigenetic Age: A Weak Spot, But I Have A Plan (14-Test Analysis) – June 6, 2024
• A Higher Kynurenine/Tryptophan Ratio Is Associated With Lower Muscle Mass – June 2, 2024
• Running A Sub-4 Minute Mile: What’s The Average Life Expectancy Increase? – May 29, 2024
• Thyroid Hormones (FT4, FT3): What’s Optimal? – May 26, 2024
• 16y Younger Biological Age: Supplements, Diet (Test #3 in 2024) – May 19, 2024
• PD Mangan: Fit At 69-Diet And Exercise Approach – May 15, 2024
• 16.1y Younger Biological Age (Blood Test #3 In 2024, Test #51 Since 2015) – May 12, 2024
• Longevity-Associated Triglycerides (7-Test Results) – May 5, 2024
• Are Turmeric And Black Pepper Bad For Health? – April 28, 2024
• Increased NAD With Clover Sprouts – April 24, 2024
• Attempting To Slow The Epigenetic Pace Of Aging (13-Test Analysis) – April 14, 2024
• Resting Heart Rate, Heart Rate Variability: What’s Optimal, 2,061 Days of Data – April 7, 2024
• Plasma Metabolites Of A Healthy Lifestyle In Relation To Mortality And Longevity – March 31, 2024
• Taurine Extends Lifespan (In Mice): What’s My Data? (6-Test Analysis) – March 24, 2024
• 19.5y Younger Biological Age: Supplements, Diet (Test #2 in 2024) – March 20, 2024
• 19.5y Younger Biological Age: My Best Data Yet (31 Tests Since 2018) – March 17, 2024
• Ergothioneine Extends Lifespan In Worms, Flies, And Mice: What About In People? – March 14, 2024
• Uric Acid: What’s Optimal For Health? – March 10, 2024
• Lung Function (FEV1) Is Associated With Alzheimer’s Disease Incident Risk – March 3, 2024
• Is Low LDL Bad For The Epigenetic Pace of Aging? – February 25, 2024
• Foods That Could Increase NAD: Fenugreek Seeds – February 21, 2024
• Telomere Length Test #12: Correlations With Diet – February 18, 2024
• RDW Is A Significant Predictor Of Biological Age: Which Factors May Optimize It? – February 14, 2024
• Biomarkers Of Kidney Function: Creatinine, Cystatin C, What’s Optimal? – February 11, 2024
• How Many Steps Are Optimal For Health? – February 7, 2024
• Blood Test #1 in 2024: What’s My Biological Age? – January 28, 2024
• Did High-Dose NMN Mess Up The Epigenetic Pace Of Aging? – January 24, 2024
• Trigonelline Increases NAD, Improves Muscle Function, And Extends Lifespan: Vincenzo Sorrentino, PhD – January 21, 2024
• How Much Dietary Fiber Is Optimal For Health? – January 17, 2024
• Tea Consumption Is Associated With Slower Biological Aging – January 7, 2024
• Telomere Length Test #7 in 2023: My Best Data Yet – December 31, 2023
• NMN vs Nicotinic Acid: Which Is Better For Increasing NAD? – December 24, 2023
• Trigonelline: Increase NAD And Melatonin, Reduce Homocysteine? – December 20, 2023
• Avoiding The Age-Related Increase For Blood Pressure – December 17, 2023
• 21 Younger Biological Age: Supplements, Diet (Blood Test #7 in 2023) – December 10, 2023
• Blood Test #7 in 2023: 15 — 21y Younger Biological Age – December 3, 2023
• Longevity-Associated Triglycerides – November 29, 2023
• Oral Microbiome Tests #8 and 9: Serratia marcescens Is Still A Problem – November 26, 2023
• Epigenetic Test #9: Finally, A Younger Horvath Age Than the Chronological – November 21, 2023
• Slow Wave Sleep % Loss Is Associated With An Increased Dementia Risk – November 15, 2023
• Conquer Aging or Die Trying Podcast, Episode #1: Crissman Loomis (@Unaging.com) – November 13, 2023
• The Kynurenine/Tryptophan Ratio: An Integrated Measure Of Many Pro- And Anti-Inflammatory Factors – November 9, 2023
• NMN Ban? No Problem, Low Dose Niacin (60 mg/d) Increases NAD – November 5, 2023
• HbA1c: What’s Optimal, What’s My Data? – November 1, 2023
• Telomere Length Test #5 in 2023: Which Dietary Factors Are Significantly Correlated? – October 29, 2023
• 23 Younger Biological Age: Supplements, Diet (Blood Test #6 in 2023) – October 22, 2023
• Acylcarnitines Increase During Aging, And Are Associated With Poor Health – October 15, 2023
• Did DunedinPACE Improve For Test #5 in 2023? Also, Is NAD Significantly Correlated With DunedinPACE? – October 10, 2023
• Higher HRV, Lower RHR: Potential Impacts For Weight Loss And Consistent Exercise Training – October 8, 2023
• Resting Heart Rate, Heart Rate Variability: Is 2023’s Data Better Than 2022? – October 5, 2023
• Cholesterol Esters: Underrated Metabolites That Are Associated With Youth And Survival – October 2, 2023
• Fish Oil Supplementation: No Impact On NAD – September 29, 2023
• Albumin, CRP, and Creatinine: Better Markers Of Longevity Than Lipoproteins And Glycemic Status – September 24, 2023
• Supplemental Tryptophan: Impact on NAD? – September 20, 2023
• Longer Telomere Length In 2023 vs 2022 (Also, Correlations With Diet) – September 13, 2023
• Calorie Restriction, Exercise, And Longevity: Luigi Fontana, MD PhD – September 10, 2023
• I’ve Got A Big Problem In My Oral Microbiome (Serratia marcescens), But Also A Plan To Reduce It – September 6, 2023
• Did Tryptophan And/Or Serine Mess Up Blood Biomarkers? (Blood Test #5 in 2023 Analysis) – September 3, 2023
• Increase NAD With Fish Oil (And Other PUFA-Containing) Fatty Acids? Hypothesis – August 23, 2023
• Uremic Metabolites: Kidney Function Biomarkers – August 20, 2023
• Is Glutamate A Marker Of Low NAD? – August 13, 2023
• Serine + Vitamin B6: No Effect On Homocysteine (Test #2) – August 9, 2023
• Tryptophan + Niacin: No Additive Effect On NAD, Relative To Niacin Alone – August 6, 2023
• How Much Junk Food Is Bad For Health? – July 30, 2023
• Circulating Levels Of Omega-3 Fatty Acids (EPA, DHA) Decline During Aging – July 26, 2023
• Niacin Increases NAD (Test Results) – July 23, 2023
• 20y Younger Biological Age: Supplements, Diet (Blood Test #4 in 2023) – July 19, 2023
• Quantifying Biological Age: Blood Test #4 In 2023 – July 16, 2023
• Grape Seed Proanthocyanidins Did Not Raise NAD (Test Results) – July 11, 2023
• 35% Increase For Heart Rate Variability Since 2018 – July 5, 2023
• Metabolite Ratios As An Index Of Oxidative Stress – July 2, 2023
• ApoB: Is Lower Always Better? – June 28, 2023
• Epigenetic Age Test #6: My Youngest Data For Horvath, DunedinPACE – June 25, 2023
• Polyamines (Including Spermidine) Extend Lifespan: What’s My Data? – June 21, 2023
• Telomere Length Test #6: Correlations With Diet – June 18, 2023
• Vitamin B6 Didn’t Impact NAD (Test Results) – June 14, 2023
• Grape Seed Proanthocyanidins Increase NAD – June 11, 2023
• Taurine Deficiency As A Driver Of Aging: What’s My Data (Youthful Or Aged)? – June 10, 2023
• HsCRP: What’s Optimal, Which Factors May Reduce It? – June 7, 2023
• Resveratrol Extends Lifespan, But Only Under Two Experimental Conditions – June 4, 2023
• Blood Test #3 in 2023: Supplements, Diet – May 28, 2023
• Oral Microbiome Test #4: Adding Berberine To The Homemade Mouthwash Was A Disaster – May 24, 2023
• Kynurenine/Tryptophan Ratio: More Insight Into The De Novo NAD Synthesis Pathway – May 21, 2023
• Vitamin B6: Did It Increase NAD? (Test Results) – May 14, 2023
• Serine + Vitamin B6: Did It Reduce Homocysteine? (Test #1) – May 10, 2023
• Quantifying Biological Age: Blood Test #3 in 2023 – May 7, 2023
• AnthropoAge: Biological Age Prediction Without Blood Testing – April 30, 2023
• Epigenetic Test #5: Impact of NMN? – April 23, 2023
• Vitamin B6: Increase NAD Without NR, NMN, or Niacin? – April 16, 2023
• Telomere Length Is Associated With Dementia Risk – April 12, 2023
• Resting Heart Rate, Heart Rate Variability: Is Q1 2023 Better Than 2022? – April 9, 2023
• Serine + Vitamin B6: The Best Way To Reduce Homocysteine? (Also, Homocysteine Activates mTORC1) – April 2, 2023
• Blood Test #2 in 2023: Diet Composition – March 26, 2023
• NAD Test #3: Impact of 1000 mg NMN/d? – March 21, 2023
• Blood Test #2 in 2023: Impact of NMN? – March 19, 2023
• Reduced Blood Pressure: Was It Caused By Lung Muscle Training? – March 13, 2023
• Exercise Timing Is Associated With All-Cause Mortality Risk – March 6, 2023
• NAD Test #2: Impact of NMN? – March 5, 2023
• Epigenetic Test #4: What’s My Biological Age? – February 26, 2023
• Blood Test #1 in 2023: Diet Composition – February 19, 2023
• Quantifying NAD: Test #1 in 2023 – February 12, 2023
• Quantifying Biological Age: Blood Test #1 in 2023 – February 5, 2023
• Green Tea Is Associated With Reduced All-Cause Mortality Risk – January 29, 2023
• Resting Heart Rate, Heart Rate Variability: What’s Optimal, 1600+ Days of Data – January 22, 2023
• Blood Test #7 in 2022: Diet Composition – January 15, 2023
• Attempting To Optimize The Oral Microbiome, Part 3: A Role For Berberine – January 8, 2023
• Will Glycine Supplementation Reduce Homocysteine? – December 27, 2022
• Quantifying Biological Age: Blood Test #7 in 2022 – December 23, 2022
• L. plantarum Increases Muscle Mass And Physical Function (Part II) – December 18, 2022
• Bacteria From An Olympic Weightlifter Improves Muscle Mass And Physical Function (In Mice) – December 11, 2022
• Methionine Restriction Extends Lifespan: Roles For SCFAs And FGF21, But Not Calorie Restriction – December 4, 2022
• Epigenetic Test #3: What’s My Biological Age? – November 27, 2022
• Kidney Function: What’s Optimal For Health (And Potentially, Longevity)? – November 20, 2022
• Longitudinal Biomarker Optimization: A Road To Maximize Health And Longevity? – November 13, 2022
• Blood Test #6 in 2022: Diet Composition (Part I) – November 6, 2022
• Dietary Fiber And SCFAs Are Relatively Higher in Centenarians-A Pathway To Longevity? – November 1, 2022
• Quantifying Biological Age: Blood Test #6 in 2022 – October 30, 2022
• Breaths Per Minute While Asleep: What’s Optimal? – October 23, 2022
• The Cholesterol-DHEA-S Experiment; A Role For Thyroid Function on DHEA-S And/Or Homocysteine? – October 16, 2022
• Improve Lung Function, Reduce Blood Pressure, Slow Brain Aging? – October 9, 2022
• Biohacking The Oral Microbiome: Test #2 – October 2, 2022
• Resting Heart Rate And Heart Rate Variability: What’s Optimal, 1,502 Days of Data – September 25, 2022
• Blood Test #5 in 2022: Supplements, Diet – September 18, 2022
• DHEA-S Is A Weakness In My Data: Blood Test #5 in 2022 – September 11, 2022
• Quantifying Biological Age: Blood Test #5 in 2022 – September 4, 2022
• Ending Age-Related Diseases 2022 Conference Presentation – August 30, 2022
• Epigenetic Tests #1 and 2: Horvath, Hannum, DunedinPACE – August 28, 2022
• Glycine + N-Acetyl Cysteine Supplementation Increases Lifespan – August 21, 2022
• Fasting Without Calorie Restriction Extends Lifespan – August 14, 2022
• Lifespan Extension With Calorie Restriction, Fasting, And Circadian Alignment – August 7, 2022
• Blood Test #4 in 2022: Supplements, Diet – July 31, 2022
• Quantifying Biological Age: Blood Test #4 in 2022 – July 24, 2022
• Biohacking the Oral Microbiome – July 17, 2022
• Lithocholic Acid: A Gut Bacterial Metabolite That Extends Lifespan – July 3, 2022
• A Bile Acid (TBMCA) Is Involved In A Mechanism That Reduces Muscle Mass And Strength – June 26, 2022
• Albumin: What’s Optimal For Youth And Health? (2022 Update) – June 19, 2022
• Bile Acids: The Next Frontier In Longevity? – June 12, 2022
• Blood Test #3 in 2022: Supplements, Diet – June 5, 2022
• Resting Heart Rate And Heart Rate Variability: What’s Optimal, 4-Year Progress – May 29, 2022
• Quantifying Biological Age: Blood Test #3 in 2022 – May 22, 2022
• A Physiology Clock for Human Aging: BP and FEV1 As Top Predictors – May 15, 2022
• Blood Test Analysis: Italian Centenarians – May 8, 2022
• Methionine Restriction Extends Lifespan-What’s Optimal For Protein Intake? n=1 Analysis – May 1, 2022
• How Much Oxalate Is Too Much? n=1 Analysis – April 24, 2022
• AGE Products Impact Lifespan: Impact Of Hyperglycemia, Kidney Function, And The Microbiome – April 17, 2022
• Calcium Intake Affects The Association For Dietary Oxalate With CVD-Event Risk – April 10, 2022
• Blood Test #2 in 2022: Diet – April 3, 2022
• Blood Test #2 in 2022: Supplements, Cardiovascular Fitness Metrics (HRV, RHR) – March 27, 2022
• Quantifying Biological Age: Blood Test #2 in 2022 – March 20, 2022
• The Association For Low LDL With An Increased CVD Mortality Risk Is Impacted – March 13, 2022
• Centenarian Blood Test Analysis (n=1,754; Part II) – March 6, 2022
• Middle-of-the-Night Melatonin Supplementation: Better Sleep, Improved HRV and RHR? – February 20, 2022
• Tracking Biomarkers of Aging – February 18, 2022
• (Part II) Supercentenarian (112 — 116y) Blood Test Analysis – February 13, 2022
• Blood Test #1 in 2022: Supplements, Fitness, Diet – February 6, 2022
• Quantifying Biological Age: Blood Test #1 in 2022 (Test #35 Since 2015) – January 30, 2022
• Supercentenarian (112 — 116y) Blood Test Analysis – January 23, 2022
• On Deck Longevity Biotech Presentation: Biological Age Optimization – January 11, 2022
• Resting Heart Rate, Heart Rate Variability: 1,240 Days Of Data – January 9, 2022
• Ergothioneine Extends Lifespan (in flies) – December 30, 2021
• Blood Test #6 In 2021: What’s My Diet? – December 25, 2021
• Quantifying Biological Age: Blood Test #6 in 2021 – December 19, 2021
• N of 1 Extend Lifespan Experiment: Evaluating Progress | Dr Lustgarten Interview Series 3 Ep 2 – December 18, 2021
• N Of 1 Extend Lifespan Experiment: How To Start | Dr Michael Lustgarten Interview Series 3 Ep 1 – December 16, 2021
• AMA Live Stream #1 – December 13, 2021
• Is Relying Solely On Data From Published Studies A Suboptimal Strategy For Optimal Health? – December 11, 2021
• How Many Calories Are Optimal For Health? – December 4, 2021
• Spermidine Impacts Health and Longevity – November 28, 2021
• How Many Steps Per Day Is Associated With Reduced Risk Of Death For All Causes? – November 24, 2021
• Physical Activity, Body Weight, And Diet Affect Resting Heart Rate And Heart Rate Variability – November 20, 2021
• Metformin Impairs Exercise Training-Related Improvements In Older Adults – November 13, 2021
• Quantifying Biological Age: Blood Test #5 in 2021 – November 8, 2021
• Ending Age-Related Diseases 2021 Presentation – November 1, 2021
• Fruit And Vegetable Intake: How Many Servings/Day Is Optimal? – October 28, 2021
• Fasting Drives The Geroprotective Effects Of A Calorie-Restricted Diet – October 23, 2021
• Chocolate Intake Is Associated With Reduced All-Cause And Cause-Specific Mortality Risk – October 16, 2021
• Epidemiological Studies vs n=1: What’s Optimal For Dietary Cholesterol? – October 10, 2021
• Dietary fibre intake is associated with increased skeletal muscle mass and strength (Paper Review) – October 3, 2021
• Attempting To Further Reduce Biological Age: hs-CRP – September 26, 2021
• Attempting To Further Reduce Biological Age: Reducing Glucose (Without Messing Up Other Biomarkers) – September 19, 2021
• Quantifying Biological Age: Blood Test #4 in 2021 – September 11, 2021
• Which Gut Bacteria Are Associated With Poor Health, And How Can We Limit Them? – August 29, 2021
• Vitamins K1 And K2 Are Associated With Cardiovascular Disease-Related Hospitalization Risk – August 20, 2021
• Homocysteine Update, What’s Optimal For Vitamin B12? – August 9, 2021
• Dietary CD38 Inhibitors: Are They Correlated With Biological Age? – July 31, 2021
• Quantifying Biological Age: Blood Test #3 in 2021 – July 27, 2021
• Epigenetic Age Reduction Within 8 Weeks: Real Effect Or Statistical Noise? – July 22, 2021
• NMN Improves Aerobic Capacity in Runners – July 17, 2021
• Lifespan Extension In Drosophila: A Conversation with Dr. Michael Rose (full, unedited video) – July 15, 2021
• Which Diet Is Optimal For Health: The Evolutionary Perspective (Part III Featuring Dr. Michael Rose) – July 12, 2021
• 100% Lifespan Extension In Drosophila: A Conversation With Dr. Michael Rose – July 8, 2021
• Aspartate Aminotransferase: What’s Optimal, And Can It Be Improved? – June 30, 2021
• Insulin Sensitivity Is A Hallmark Of Longevity – June 21, 2021
• Selenium: How Much Is Optimal For Health? – June 15, 2021
• SIRT6 Positively Affects The Hallmarks Of Aging And Extends Lifespan – June 6, 2021
• High FGF21, Low Insulin And Glucose: A Pro-Longevity Strategy? – May 30, 2021
• Are There Foods That Can Increase NAD? (Part II) – May 22, 2021
• VLDL Increases During Aging, And Is Associated With Adverse Cardiovascular Outcomes – May 16, 2021
• Homocysteine Increases During Aging, But Can Be Reduced With Diet And Targeted Supplementation – May 9, 2021
• Quantifying Biological Age: Blood Test #2 in 2021 – May 2, 2021
• C-Reactive Protein: What’s Optimal? A Comprehensive Review – April 25, 2021
• Ergothioneine: A ‘Longevity Vitamin’ With Potential Benefits For Age-Related Outcomes? – April 18, 2021
• Glutathione Restoration Improves Hallmarks Of Aging in Older Adults – April 11, 2021
• Gut Bacteria Boost Host NAD Metabolism – April 4, 2021
• Telomere Length: How Does it Compare Against Other Biological Age Metrics? – March 28, 2021
• HDL Update: Age-Related Changes, All-Cause Mortality Risk, And Progress Towards The Optimal Range – March 21, 2021
• Carotenoids Are Associated With A Younger Epigenetic Age And Reduced All-Cause Mortality Risk – March 14, 2021
• Quantifying Biological Age: Blood Test #1 in 2021 – March 7, 2021
• Pneumonia Is A Major Cause of Death In Centenarians: Reducing Risk Via The Gut Microbiome – February 22, 2021
• Microbes Affect The Hallmarks Of Aging: Mitochondrial Dysfunction (Part II) – January 30, 2021
• Quantifying Biological Age With Aging.ai: 24 Blood Tests Since 2009 – January 22, 2021
• Microbial Products Affect the Hallmarks Of Aging: 1) Mitochondrial Function – December 27, 2020
• LDL: What’s Optimal For Health And Longevity? – December 15, 2020
• HDL: What’s Optimal For Minimizing Disease Risk And Maximizing Longevity? – November 25, 2020
• Kidney Function: The Missing Link In The TMAO-Health And Disease Story? – November 19, 2020
• Longevity Genes – November 11, 2020
• Quantifying Biological Age: Blood Test #5 in 2020 – November 5, 2020
• Slower Biological Aging In People On A Calorie Restricted Diet – October 30, 2020
• Biological Age: Optimal On A Carnivore Diet? – October 23, 2020
• Deep Sleep: How Does It Change During Aging, What’s Its Connection To Alzheimer’s Disease? – October 16, 2020
• Epigenetic Clocks: Which Has The Best Correlation For Aging and Age-Related Diseases? – September 27, 2020
• Blood Test Analysis: 100 — 111y (Centenarians, Semi- and Super-Centenarians) – September 26, 2020
• Dietary AGE Products Impact Insulin Resistance, Inflammation, And Lifespan – September 8, 2020
• The Impact Of The Microbiome On Lifespan – September 2, 2020
• Fungi In The Blood, Fungi In The Brain: Rapamycin To The Rescue? – August 27, 2020
• Calorie Restriction vs. Rapamycin: Which Is Better at Extending Maximal Lifespan? – August 21, 2020
• Biological Age Test #4 in 2020: Getting Better or Getting Worse? – August 19, 2020
• CD38 gets in the way of NR and NMN for increasing NAD+ – August 18, 2020
• Low Total Cholesterol: Biological Youth Or Increased Mortality Risk? – August 17, 2020